Clinical trials: Hypertension,Essential
Hypertension
A Study of Nifecardia SRFC and Adalat OROS in the Treatment of Patients With Essential Hypertension
Objective: To evaluate the antihypertensive efficacy of two brands of nifedipine 30mg in patients with hypertension. To assess the safety of 8 weeks of therapy with two brands of nifedipine 30mg in patients with hypertension.
- Trial name
- NCT00173667
- Testing
- Nifedipine 30 mg GITS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Hypertension
The Clinical Study to Evaluate the Efficacy and Safety of Fimasartan in Patients With Mild to Moderate Essential Hypertension
The purpose of this clinical study is to evaluate and compare the efficacy and safety of Fimasartan (60mg / 120mg) with Candesartan(8mg) in patients with mild to moderate hypertension.
- Trial name
- NCT01135212
- Testing
- Fimasartan 60mg, Fimasartan 120mg, Candesartan cilexetil
- Where
- South Korea
- Volunteers
- 290 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Essential Hypertension, Primary Hypercholesterolemia
A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia
The objective of this clinical study is to evaluate the efficacy and safety by comparing BR1017A+BR1017B treatment group to BR1017A treatment group and BR1017B treatment group respectively at Week 8 in essential hypertension…
- Trial name
- NCT05930028
- Testing
- Fimasartan, Ezetimibe/Atorvastatin
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension,Essential
Licorice and Home Blood Pressure
Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure.
- Trial name
- NCT05661721
- Testing
- Sweet licorice, Salty licorice
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Essential Hypertension, Healthy Volunteers
Phase 1 Clinical Study of MWX401 Injection in Chinese Healthy Participants and Participants With Mild Hypertension
This is a single-center, randomized, double-blind, placebo-controlled, single ascending-dose phase 1 clinical study, aimed at evaluating the safety, tolerability, PK, PD and immunogenicity of single subcutaneous administration of…
- Trial name
- NCT07803835
- Testing
- MWX401 1, MWX401 2, MWX401 3
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Essential Hypertension
Effectiveness and Patient Self-assessed Compliance of Blood Pressure Treatment With Tarka® Fixed Combination in Patients With Essential Hypertension
The fixed combination of verapamil SR/trandolapril (Tarka®) is an effective, well-tolerated therapy for the treatment of essential hypertension in those who require more than one agent to achieve optimal blood pressure (BP)…
- Trial name
- NCT01127139
- Where
- 134 sites in Czechia
- Volunteers
- 3,828 people
- Sponsor
- Abbott
Diseases of the Circulatory System, Essential Hypertension
To Evaluate the Drug-drug Interaction Between Telmisartan and Atorvastatin in Healthy Male Volunteers
The study design was composed of 2 parts, 2-way crossover and multiple-dose. There are having 2 groups in each part that have divided period 1 and period 2, and wash-out period is 16 days between periods.
- Trial name
- NCT02579356
- Testing
- Telmisartan, Atorvastatin
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samil Pharmaceutical Co., Ltd.
Hypertension
FOCUS (Nifedipine GITS's Effect on Central Pressure Assessed by Applanation Tonometry)
To determine whether the combination of nifedipine GITS and valsartan is more effective in reducing central blood pressure than nifedipine GITS or valsartan alone, and to determine whether nifedipine GITS is comparable to…
- Trial name
- NCT01071122
- Testing
- Nifedipine (Adalat, BAYA1040) and Valsartan, Nifedipine (Adalat, BAYA1040), Valsartan
- Where
- 15 sites in South Korea
- Volunteers
- 365 people
- Sponsor
- Bayer
Atrial Fibrillation, Hypertension,Essential
Left Atrial Enlargement: A Crucial Indicator for Identifying Atrial Fibrillation in Patients With Hypertension
Based on the data of inpatients with hypertension and a cross-sectional study with a large sample size, this study aims to find the early warning value of the left anteroposterior atrial diameter for the possible occurrence of…
- Conditions
- Atrial Fibrillation, Hypertension,Essential, Left Atrial Dilatation
- Trial name
- NCT06359873
- Testing
- CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
- Where
- China
- Volunteers
- 58,427 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Hypertension
Efficacy and Safety of Azilsartan in Subjects With Essential Hypertension
The purpose of this study is to determine the safety and efficacy of azilsartan, once daily (QD), in subjects with essential hypertension.
- Trial name
- NCT00759551
- Testing
- Azilsartan, Olmesartan
- Volunteers
- 555 people
- Sponsor
- Takeda
High Blood Pressure (Hypertension).
Factorial Study of Metoprolol Succinate TOPROL-XL (324A)
The purpose of this research study is to determine if treatment with the combination of metoprolol succinate and hydrochlorothiazide is more effective at lowering blood pressure than treatment with either of the two drugs alone.
- Trial name
- NCT00642096
- Testing
- Metoprolol Succinate, Hydrochlorothiazide
- Volunteers
- 1,900 people
- Sponsor
- AstraZeneca
Hypertension
A Clinical Study to Evaluate the Long-term Safety (12 Months) of the Combination of Aliskiren 300 mg and Hydrochlorothiazide 25 mg
The purpose of this study is to collect the long-term (12 months) safety data on aliskiren 300 mg when taken in combination with HCTZ 25 mg.
- Trial name
- NCT00171405
- Testing
- aliskiren
- Where
- 10 sites in United States, Belgium and 8 more
- Volunteers
- 250 people
- Sponsor
- Novartis
Hypertension, Genetic Predisposition
Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment
Phase III interventional study to evaluate the different efficacy of Torasemide and Spironolactone in reducing systolic blood pressure in carriers and non-carriers of the different genotypic combinations for Lanosterol and…
- Conditions
- Hypertension, Genetic Predisposition, Drug Effect
- Trial name
- ALTUM (NCT06413082)
- Testing
- Torasemide, Spironolactone
- Where
- 2 sites in Italy
- Volunteers
- 38 people
- Sponsor
- Ospedale San Raffaele
Essential Hypertension
Study MIPAE - Melatonin and Essential Arterial Hypertension
Study MIPAE - Melatonin and essential arterial hypertension. Study with dietary supplement, prospective and monocentric (randomized control trial).
- Trial name
- MIPAE (NCT05257291)
- Testing
- Melatonin
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Hypertension, Aromatherapy
The Effect of Aromatherapy on Sleep, Anxiety and Vital Signs in Those With Essential Hypertension (Hypertension)
In addition to pharmacological agents in the treatment of hypertension, it has been reported in studies that aromatherapy applications, one of the traditional and complementary alternative treatments that are easy to apply…
- Trial name
- hypertension (NCT06482424)
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- TC Erciyes University
Hypertension, Resistant to Conventional Therapy, Essential Hypertension
Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension
To test whether the current custom of initiating treatment for hypertension with a single drug is less effective in the short-term than initial combination therapy, and results in the eventual need for comparatively more…
- Trial name
- Pathway 1 (NCT00994617)
- Testing
- Losartan and hydrochlorothiazide, Hydrochlorothiazide switched over with Losartan at 8 weeks
- Where
- 13 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- University of Cambridge
Stage 1 Hypertension, Stage 2 Hypertension
Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension
To evaluate the efficacy and safety of fixed-dose combination of nebivolol and valsartan compared to monotherapy and placebo in patients with stage 1 and stage 2 hypertension.
- Trial name
- NCT01508026
- Testing
- Nebivolol and Valsartan 1, Nebivolol and Valsartan 2, Nebivolol and Valsartan 3
- Where
- 413 sites in United States
- Volunteers
- 4,161 people
- Sponsor
- Forest Laboratories
Essential Hypertension
A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Hypertensive Subjects
This study is a randomized, placebo-controlled, double-blind, multi-center study to evaluate efficacy and safety of different doses of CS-3150 compared to placebo in Japanese hypertensive subjects.
- Trial name
- NCT02345044
- Testing
- CS-3150, eplerenone
- Where
- Japan
- Volunteers
- 426 people
- Sponsor
- Daiichi Sankyo
Essential Hypertension
To Assess Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine or Allisartan Isoproxil
The main objective of the study will be to assess the efficacy and safety of Allisartan Isoproxil/Amlodipine (240 mg/5 mg) in patients with mild to moderate essential hypertension uncontrolled after 4-week treatment with…
- Trial name
- NCT06465264
- Testing
- Allisartan Isoproxil/Amlodipine group 1, Amlodipine group 1, Allisartan Isoproxil/Amlodipine group 2
- Where
- China
- Volunteers
- 499 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure
The Effect of Eye Movement Desensitization and Reprocessing Intervention in Hypertension Patient.
Eye Movement Desensitization and Reprocessing intervention may improve anxiety, depression, systolic blood pressure and heart rate variability in patients with hypertension.
- Conditions
- Eye Movement Desensitization and Reprocessing Intervention, Blood Pressure, Heart Rate Variability, Anxiety
- Trial name
- EMDR (NCT05836181)
- Testing
- Eye Movement Desensitization and Reprocessing
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Miao-Yi Chen