Clinical trials: Hyperspectral Imaging
Preeclampsia (PE) Risk, Preeclampsia
Hyperspectral Imaging for Prediction of Preeclampsia
Preeclampsia is a hypertensive pregnancy disorder that can quickly lead to serious, potentially life-threatening outcomes for both the mother and the fetus.
- Trial name
- HIPPA (NCT07106294)
- Where
- Germany
- Volunteers
- 1,430 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Kidney Neoplasm, Renal Mass up to 7cm
Hyperspectral Imaging in Robot-Assisted Partial Nephrectomy
The goal of this prospective observational study is to learn about the use of a novel imaging technique called hyperspectral imaging in adult participants who are having surgery for removing a tumor from their kidney.
- Trial name
- HSI-Renal (NCT07803315)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Cellulite, Gynoid Lipodystrophy
Quantitative Assessment of the Efficacy of Alidya
This study evaluated the efficacy of ALIDYA, a Class III medical device used in needle mesotherapy, for the treatment of cellulite (gynoid lipodystrophy) in women.
- Trial name
- NCT07675356
- Testing
- ALIDYA
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Quantitative Validation of Imaging System
Non Invasive and Non-Contact Imaging Of Tissue Oxygenation and Vascular Reactivity
1. Quantitative validation of non-contact oxygenation imaging by the CWC imaging system 2. Quantitative validation of non-contact vascular function imaging by the CWC imaging system 3.
- Trial name
- NCT01573390
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chandan K Sen
Parkinsons Disease (PD)
Non-invasive Diagnosis of Parkinson's Disease
This study will investigate new, non-invasive methods to help diagnose Parkinson's disease. Researchers will use advanced eye imaging (hyperspectral retinal photography and OCT), computerized memory and thinking tests, and voice…
- Trial name
- NCT07201610
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Preeclampsia (PE), Hypertensive Disorder of Pregnancy
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus.
- Trial name
- EPICS (NCT06912477)
- Testing
- Hyperspectral imaging, Further markers of endothelial dysfunction
- Where
- Germany
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Breast Cancer
Intraoperative Margin Assessment in Breast Cancer With HSI-Raman
Breast-conserving surgery (lumpectomy) aims to remove cancer while preserving healthy tissue, but up to 20% of patients require a second operation because cancer cells remain at the edge (margin) of the removed tissue.
- Trial name
- Spectra-BREAST (NCT07111728)
- Testing
- Spectra-BREAST system in Invasive Breast Cancer, Spectra-BREAST system in DCIS Breast Cancer
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Neurosurgery, Neurovascular
Intra-operative Hyperspectral Imaging in Neurosurgery
Brain surgery operations include brain tumour removal and blood vessel procedures. Each year in the UK, approximately 70,500 patients are diagnosed with a brain tumour, 5,000 of whom undergo surgery.
- Conditions
- Neurosurgery, Neurovascular, Neuro-Oncology
- Trial name
- NeuroHSI (NCT05294185)
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- King's College London
Alzheimer Disease, Dementia Alzheimers
Optical Coherence Tomography in Cerebral Amyloidosis
In this observational study, the investigators aim to evaluate whether changes in the retinal and choroidal circulation, as assessed by Optical Coherence Tomography (OCT) and the quantification of retinal amyloid deposits using…
- Conditions
- Alzheimer Disease, Dementia Alzheimers, Dementia, Lewy Body Disease
- Trial name
- NCT03472482
- Testing
- non-invasive retinal imaging
- Where
- Belgium
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Idiopathic Membranous Nephropathy, Tacrolimus
Study on the Application of Hyperspectral Imaging Technique in the Treatment of IMN by TAC
We propose hyperspectral imaging analysis as a method to identify the efficacy of hormone-tacrolimus therapy for PMN, and to classify sensitive and insensitive patients treated with hormone-tacrolimus regimen.
- Conditions
- Idiopathic Membranous Nephropathy, Tacrolimus, Hyperspectral Imaging
- Trial name
- NCT05797038
- Testing
- Tacrolimus for the treatment of IMN
- Volunteers
- 40 people
- Sponsor
- Qianfoshan Hospital
Actinic Keratoses
Daylight-mediated Photodynamic Therapy of Actinic Keratoses:Comparing 0.2%HAL With 16%MAL
This pilot study compares two photosensitizers, hexylaminolaevulinate (HAL) and methylaminolaevulinate (MAL), in treatment of actinic keratoses. Study is conducted using randomized split-face design.
- Trial name
- NCT02149342
- Testing
- Hexylaminolaevulinate cream, Methylaminolaevulinate cream
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Brain (Nervous System) Cancers, Brain Tumor, Primary
3D Decision Support Tool for Brain Tumour Surgery Development and Validation: Observational Study
This observational study (STRATUM-OS) aims to collect the necessary data from a cohort of patients with planned surgery for suspected intra-axial malignant brain tumours (both primary and secondary) following the standard…
- Trial name
- STRATUM-OS (NCT07036783)
- Volunteers
- 320 people
- Sponsor
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias
Hyperspectral Imaging Data of Excreta
Hyperspectral Imaging for Neoplasm Early Stage Detection
Background Information With the advance in cancer biology, we realize that malignant neoplasm is related with different biological patterns in metabolome and microbiota.
- Trial name
- HINED (NCT03483974)
- Testing
- hyperspectral imaging
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Diabetic Foot Ulcers
Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers
This study is designed to test a prototype imaging instrument that relies on Medical HyperSpectral Imaging (MHSI) technology for the assessment and prediction of diabetic foot ulceration and wound healing.
- Trial name
- NCT00617916
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- HyperMed
Neurosurgery, Neuro-Oncology
Intraoperative Hyperspectral Imaging for Fluorescence Guided Surgery in Low Grade Gliomas
The purpose of this study is to obtain images of brain tumours during surgery using a new type of surgical camera. The study will assess how the information obtained from the images during surgery matches the removed tissue.
- Conditions
- Neurosurgery, Neuro-Oncology, Brain Tumor
- Trial name
- Neuro-qFHSI (NCT05397574)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Colonic Polyp, Colonic Diseases
Optical Polyp Testing for In Vivo Classification
Small growths detected in the colon (polyps) during a colonoscopy may or may not have the potential to develop into cancer. However, since visual inspection alone cannot separate all potentially harmful polyps from harmless ones…
- Conditions
- Colonic Polyp, Colonic Diseases, Colonic Neoplasms, Colonic Adenoma
- Trial name
- OPTIC (NCT03139942)
- Testing
- Optical spectral reflectance and autofluorescence imaging
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Lentigo Maligna
Photodynamic Therapy for Lentigo Maligna Using 5-aminolevulinic Acid Nanoemulsion as a Light Sensitizing Cream
This study investigates the efficacy of photodynamic therapy (PDT) in the treatment of lentigo maligna (LM). Hyperspectral imaging system (HIS) will be used to determine the margins of LM and to rule out possible invasion.
- Trial name
- LM PDT (NCT02685592)
- Testing
- 5-aminolevulinic acid nanoemulsion
- Where
- Finland
- Volunteers
- 10 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Colorectal Cancer
Endoscopic Optical Imaging for Precision Oncology Treatment Applied to Colorectal Tumours (Elios-Color-on-Specimen)
The Institute of Image-Guided Surgery (IHU) of Strasbourg is a translational research Institute aiming to develop hybrid surgery techniques.
- Trial name
- NCT04101292
- Testing
- Characterization of tumor tissue by fluorescence
- Sponsor
- IHU Strasbourg
Alzheimer Disease
Retinal Metabolic Imaging of Alzheimer Patient
This research project concerns the evaluation of the Metabolic Hyperspectral Retinal Camera (MHRC), a novel medical instrument from Optina Diagnostics, for the detection of beta-amyloid plaques, a hallmark of Alzheimer's disease…
- Trial name
- NCT03420807
- Testing
- MHRC
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Optina Diagnostics Inc.