Clinical trials: Hyperopia and Myopia
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hyperopia, Myopia
A Phase 1/2 Crossover Study to Assess EXP039 for Myopia or Hyperopia
Assess the Safety, Pharmacodynamics, and Efficacy of EXP039 Ophthalmic Solution in Participants with Myopia or Hyperopia
- Trial name
- NCT04883996
- Testing
- 1% EXP039, Saline control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Canyon City Eyecare
Myopia, Conjunctivitis
Zanzibar Arts for Children's Eyesight Pilot Trial
In Zanzibar, around 22,000 children (4% of those aged 6 to 12) need treatment for eye issues like conjunctivitis or require glasses. A 2017 study found that 42% of rural children needing glasses didn't have them.
- Conditions
- Myopia, Conjunctivitis, Hyperopia
- Trial name
- ZANZI-ACEII (NCT06469697)
- Testing
- School music broadcast, Community music broadcast
- Where
- Tanzania
- Volunteers
- 1,295 people
- Sponsor
- Queen's University, Belfast
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser Using LASIK
This clinical study has been planned to evaluate the safety and effectiveness of a common treatment algorithms (Proscan) using 500 Hz laser repetition rate.
- Trial name
- NCT02071576
- Testing
- Proscan
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Technolas Perfect Vision GmbH
Myopia, Hyperopia
Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY
This study is an observational registry of patients who have recently been prescribed 1•DAY ACUVUE® TruEye® or 1•DAY ACUVUE® MOIST® Brand Contact Lenses with LACREON® TECHNOLOGY.
- Trial name
- TEMPO (NCT01467557)
- Testing
- narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
- Where
- 37 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Myopia, Hyperopia
Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure
By using a new software two consecutive laser treatments have been combined to correct the distance vision and to provide a near vision component in addition to the first treatment.
- Conditions
- Myopia, Hyperopia, Presbyopia, Refractive Error
- Trial name
- Supracor (NCT01322919)
- Testing
- Supracor
- Where
- Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Refractive Errors
Seeing to Learn in Sierra Leone
The main objective of the Sierra Leone Sees to Learn (SL2) trial is to assess the educational impact of providing free eyeglasses to students aged 9-20 years with uncorrected refractive error in Sierra Leone.
- Trial name
- SLII (NCT06065631)
- Testing
- Eyeglasses, Prescription slip
- Where
- Sierra Leone
- Volunteers
- 1,821 people
- Sponsor
- University of Minnesota
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Astigmatism, Myopia
Short-term Study of Two Soft Contact Lenses in Wearers With Low Astigmatism
The primary objective of the study is to evaluate and compare the performance of two soft contact lens.
- Conditions
- Astigmatism, Myopia, Hyperopia
- Trial name
- NCT06873048
- Testing
- Control Contact Lens (stenfilcon A Sphere), Test Contact Lens (stenfilcon A Toric)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Nearsightedness, Farsightedness
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
The principle investigator is evaluating self-reported quality of vision and quality of life in physicians undergoing LASIK, SMILE and PRK surgery.
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT02576483
- Testing
- Questionnaire (QoV questionnaire)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Presbyopia
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Study of safety and efficacy of UNR844 in subjects with presbyopia.
- Trial name
- READER (NCT04806503)
- Testing
- UNR844
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 234 people
- Sponsor
- Novartis Pharmaceuticals
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia
This clinical study has been planned to evaluate the safety and effectiveness of common treatment algorithms using 500 Hz laser repetition rate for the correction of Ammetropia and Presbyopia
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- NCT02112968
- Testing
- Proscan, Zyoptix, Supracor
- Volunteers
- 97 people
- Sponsor
- Technolas Perfect Vision GmbH
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Anisometropia, Hyperopia
Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia
Photorefractive keratectomy (PRK) with excimer laser has been used successfully to treat myopia, hyperopia, and astigmatism in adults for over 35 years.
- Conditions
- Anisometropia, Hyperopia, High Myopia, Amblyopia Isometropic
- Trial name
- NCT03610997
- Testing
- Photorefractive keratectomy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor College of Medicine
Hyperopia and Myopia
Eye Imaging for the Study of Childhood Myopia
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic.
- Trial name
- SELENA (NCT07335146)
- Testing
- Ophtalmic measurements to estimate geometrical distances, MRI, Ophtalmic measurements to measure wavefront aberrations
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.