Clinical trials: Hyperinsulinemia
Overweight (BMI > 25), Obesity & Overweight
Gummy Candies With Maqui Berry
The goal of this clinical trial is to learn if Maqui berry gummy encapsulated (GMM) compared to non-encapsulated (GM) can improve glycemic response in overweight adults.
- Conditions
- Overweight (BMI > 25), Obesity & Overweight, Insulin Resistance Syndrome, Type 2 Diabetes
- Trial name
- MaquiGUM (NCT07373795)
- Testing
- GM, Control, GMM
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Gonzalo Jorquera, PhD
Diabetes
Improving Insulin Therapy With Enhanced Care Management
VA diabetes patients often have difficulty managing their self-care and accessing clinic-based services; many also lack social support to help them meet the demands of their illness.
- Trial name
- NCT00320112
- Testing
- Reciprocal Diabetes Peer Support Program, Nurse Case management, group outpatient counseling visits
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- US Department of Veterans Affairs
Metabolic Syndrome
Postprandial Glucose, Insulin Responses and Appetite Hormones to Dried Mushrooms
Obesity, characterized by an increase in body weight that results in excessive fat accumulation, is a global health problem. Recently, it has also been shown that obesity is associated with low-grade chronic systemic inflammation…
- Trial name
- NCT04444219
- Testing
- Breakfast meals
- Where
- Greece
- Volunteers
- 19 people
- Sponsor
- Harokopio University
Metabolic Syndrome, Inactivity/Low Levels of Exercise
Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial
This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes.
- Conditions
- Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use
- Trial name
- LifeHealth-RCT (NCT07314957)
- Testing
- Intervention of physical activity, Mediterranean Diet Education, Behavioral: Stress-Resilience Training
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Metabolic Syndrome
Acute Effects of Tocotrienols on Insulin Sensitivity and Metabolic Risk Markers in Individuals at Risk for Metabolic Syndrome
Objectives: To compare the acute effects of gamma delta rich tocotrienol fractions (gd-TRF) on insulin sensitivity, metabolic risk markers and postprandial lipemia in individuals at risk for metabolic syndrome.
- Trial name
- NCT01626430
- Testing
- Gamma delta TRF
- Where
- 2 sites in Malaysia
- Volunteers
- 30 people
- Sponsor
- Malaysia Palm Oil Board
Metabolic Syndrome
Study of TNF-Antagonism in the Metabolic Syndrome (II)
This study will investigate whether etanercept will result in improved inflammatory indices, glucose tolerance and endothelial function in patients with the metabolic syndrome.
- Trial name
- NCT00413400
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Periodontal Disease, Metabolic Syndrome
The Relation Between Periodontal Disease and Metabolic Syndrome
Periodontal disease is associated with the components of Metabolic syndrome, such as obesity, diabetes, hypertension and hyperlipidemia. Therefore, strong relation with periodontal disease and metabolic syndrome is suggested.
- Trial name
- NCT00553007
- Testing
- Periodontal therapy
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Aichi Gakuin University
Metabolic Health, Insulin Sensitivity/Resistance
Defining the Human Insulin Resistance Molecular Network; SIGNATURE
The goal of this intervention study is to learn more about what causes insulin resistance in otherwise healthy adults, and how short-term changes in physical activity or diet may influence it.
- Trial name
- SIGNATURE (NCT07255807)
- Testing
- Physical Inactivity, Hypercaloric High-Fat Diet
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Insulin Resistance, Metabolic Syndrome X
The Health Effects of Blueberry Anthocyanins in Metabolic Syndrome (the CIRCLES-study)
The purpose of this study is to determine the dose-dependent impact of 6 month freeze-dried blueberry powder intake on insulin sensitivity and resistance, cardiovascular disease risk factors, and lung and cognitive function in…
- Trial name
- CIRCLES (NCT02035592)
- Testing
- Full dose blueberry, Half dose blueberry, Control
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 144 people
- Sponsor
- University of East Anglia
Obesity & Overweight, Insulin Resistance Syndrome
SENSILINS: Impact of Cephalic Phase Insulin Release Induced by an Environmental Food Odor Stimulus on Glucose Homeostasis According to Insulin Sensitivity Level
This single-center, randomized, single-blind, 2-period crossover interventional study will evaluate whether exposure to a pleasant food odor 10 minutes before a 75 g oral glucose tolerance test (OGTT) modifies glucose homeostasis…
- Trial name
- SENSILNS (NCT07638111)
- Testing
- Pleasant Food Odor Stimulation, Control Environmental Condition
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Metabolic Syndrome, Obese
Exercise, Statins, and the Metabolic Syndrome
Here we tested if statins or exercise plus statins had a greater capacity to lower metabolic syndrome risk factors in sedentary individuals with at least 2 metabolic syndrome risk factors.
- Conditions
- Metabolic Syndrome, Obese, Sedentary
- Trial name
- NCT01700530
- Testing
- Statin, Exercise only, Statins + Exercise
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Chronic Obstructive Pulmonary Disease, Hyperglycemia
Insulin Therapy in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
The purpose of this study is to determine the effect of preventing hyperglycaemia in patients admitted to hospital with acute exacerbations of chronic pulmonary disease.
- Trial name
- NCT00467636
- Testing
- Blood glucose monitoring, Insulin Glulisine
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- The Royal Bournemouth Hospital
Septic Shock, Sepsis
Insulin Resistance in Stress-metabolic Medical Patients
An observational study on the insulin resistance in sepsis and septic shock patients.
- Conditions
- Septic Shock, Sepsis, Insulin Resistance
- Trial name
- NCT04239937
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Slagelse Hospital
Insulin Sensitivity
Insulin Signaling in Skeletal Muscle
The insulin sensitizing effects of metformin and pioglitazone in the skeletal muscle remain unknown. Our group aims to analyze molecular changes within the skeletal muscle of pre-diabetic patients through the use of a clinical…
- Trial name
- NCT03452267
- Testing
- Metformin, Pioglitazone
- Sponsor
- Wayne State University
Insulin Resistance, Hyperglycemia
A Cold Physical Treatment to Manage Insulin Resistance
Insulin resistant volunteers will choose to undergo an 8-week cold treatment, 2 hours per day, to selective regions of the body enriched with brown fat including neck, supraclavicular and interscapular regions) in combination…
- Conditions
- Insulin Resistance, Hyperglycemia, Hyperinsulinemia, Diabetes
- Trial name
- CTPMIR (NCT02852759)
- Testing
- Selective Cold, Electroacupuncture
- Where
- China
- Volunteers
- 33 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Regulation, Appetite, Eating Behavior
Impact of Different Breakfast Meals on Food Choices, Eating Behaviors and Brain Activation
This project aims to demonstrate that the best breakfast meal is the one able to improve the best postprandial hunger, satiety and adiposity regulators profile as well as the best reward-related gratification, due to hedonistic…
- Conditions
- Regulation, Appetite, Eating Behavior, Cognition
- Trial name
- NCT02516956
- Testing
- Breakfast consumption, Blood tests, Food choices and energy intakes assessments
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Parma
Obesity, Metabolic Syndrome
Integrated Traditional Chinese Medicine Day Care Program for Metabolic Syndrome
The goal of this study is to evaluate if a integrated tradtional Chinese medicine (TCM) program for improving metabolic syndrome is applicable.
- Conditions
- Obesity, Metabolic Syndrome, Dyslipidemias, Diabetes Mellitus
- Trial name
- NCT06703788
- Testing
- A fiixed combination of Chinese herbal medicine, Laser acupuncture
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy, Glucose Metabolism Disorders
Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals
Asians tend to develop type 2 diabetes (T2D) at lower body mass index (BMI) levels and younger ages compared to other populations.
- Conditions
- Healthy, Glucose Metabolism Disorders, Obesity, Visceral, Obesity; Endocrine
- Trial name
- MONW (NCT06802341)
- Testing
- Normal protein diet, Animal protein diet, Plant based diet
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Insulin Resistance
Efficacy and Safety of D-chiro-inositol in Obese Patients
The study aims to evaluate the efficacy and tolerability of a food supplement based on D-chiro-inositol in overweight or obese women with insulin resistance, who are approaching a hypocaloric diet
- Trial name
- NCT05348941
- Testing
- TECADRIOL
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Lo.Li.Pharma s.r.l
Insulin Sensitivity
The Effect of Blueberries on Enhancing Insulin Sensitivity in Humans: A Pilot Study
The purpose of this study is to evaluate the effect of blueberry powder on insulin sensitivity in obese, non-diabetic, and insulin resistant subjects.
- Trial name
- BLUEBERRY (NCT01005420)
- Testing
- Blueberry Powder
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center