Clinical trials: Hyperhidrosis
Axillary Hyperhidrosis
Comparison of the Clinical Efficacy and Adverse Reactions of Different Needling Patterns of High-frequency Microneedles in the Treatment of Axillary Odor
Background: Axillary osmidrosis is a common skin disease characterized by an unpleasant odor produced when secretions from apocrine sweat glands in the armpits are decomposed by bacteria on the skin.
- Trial name
- NCT07094009
- Testing
- received transverse needling, received vertical needling, received mixed needling
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Hyperhidrosis
Evaluate the Efficacy of Oxybutynin Chloride in Patients With Primary Hyperhidrosis
Treatment of primary hyperhidrosis through a comparative study between oxybutynin hydrochloride and placebo. Hydrochloride may decrease the symptoms of hyperhidrosis improving the subject's quality of life.
- Trial name
- NCT02099695
- Testing
- Oxybutynin
- Where
- 2 sites in Brazil
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Primary Focal Hyperhidrosis of the Hands
BTX-A Treatment for Palmar Hyperhidrosis
Primary focal hyperhidrosis (excessive sweating) is a debilitating condition affecting approximately 3% of the population in the United States.
- Trial name
- NCT01262339
- Testing
- BTX-A
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Hyperhidrosis
Assessing the Effect of Patient Characteristics on Treatment Response in Primary Hyperhidrosis
This study will describe the treatment of hyperhidrosis (excessive sweating) in clinical practice and explore the effect of patient characteristics on treatment response.
- Trial name
- NCT03694093
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- St. Louis University
Antidepressant Induced Excessive Sweating
Pilot Study of Terazosin in Treatment of Antidepressant Induced Excessive Sweating
This study is based on the hypothesis that terazosin, a blocker of alpha-1 receptors, will be effective in reducing excessive sweating caused by antidepressant treatment, and will have minimal adverse effects.
- Trial name
- NCT00237510
- Testing
- terazosin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Thomas Jefferson University
Dermatoses, Vestibulodynia
Treatment and Mapping of Impostor Phenomenon
The aim of this study is to evaluate persons/patients with different skin diseases or pain to evaluate whether unhealthy perfectionism, stress, anxiety, impostor phenomenon (inability to realistically assess your competence and…
- Conditions
- Dermatoses, Vestibulodynia, Hyperhidrosis, Pain Syndrome
- Trial name
- NCT05805696
- Testing
- Impostor tasks
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Primary Palmar Hyperhydrosis
Bilateral Endoscopic Thoracic T3 Sympathectomy Versus T3 Radiofrequency Ablation for Primary Palmar Hyperhidrosis
Primary hyperhidrosis disease is characterized by much more sweating above the needs for thermoregulation, which is worsen by increased temperature and emotional factors it can be seen in the palms of the hands, soles of the…
- Trial name
- NCT05737914
- Testing
- Endoscopic thoracic T3 sympathectomy, ThoracicT3 radiofrequency ablation
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Primary Focal Hyperhidrosis, Axilla
Efficacy and Safety of the DTS-G2 System in Patients With Axillary Hyperhidrosis
This is a prospective, multi-center, parallel, randomized, blinded study. The study has two groups, where in one study group the subjects receive treatment for axillary hyperhidrosis (excessive underarm sweating) with the DTS-G2…
- Trial name
- DRI-UP (NCT00931359)
- Testing
- DTS-G2 System
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Miramar Labs
Hyperhidrosis, Residual Limbs
Topical Aluminium Chloride vs OnabotulinumtoxinA Intradermal Injections in Residual Limb Hyperhidrosis (Lower Limbs)
The aim of this study is to demonstrate onabotulinumtoxinA superiority to aluminium chloride for the treatment of residual limb hyperhidrosis.
- Trial name
- SALUTOX (NCT03433859)
- Testing
- OnabotulinumtoxinA, Topical Aluminium Chloride (cosmetic product)
- Where
- 9 sites in France
- Volunteers
- 54 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Hyperhidrosis
Evaluation of 1440nm Laser Assisted Selective Photothermolysis for Treatment of Axillary Hyperhidrosis
The purpose of this study is to evaluate the safety and efficacy of the Nd:YAG 1440 nm wavelength laser for the treatment of primary hyperhidrosis of the axilla.
- Trial name
- NCT02100072
- Testing
- Nd:YAG 1440 nm laser
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Cynosure, Inc.
Hyperhidrosis
The Use of Topical Oxybutynin 10% for Treating Primary Focal Hyperhidrosis-axillary, Palmar and Plantar.
Primary focal hyperhidrosis interferes with daily activities. Limited efficacy, costs, side effects and complications are issues of concern for most current therapeutic modalities.
- Trial name
- NCT02973659
- Testing
- Oxybutynin
- Volunteers
- 61 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hyperhidrosis
GSK1358820 (Botulinum Toxin A) PhIII DB & OL Study in Patients With Axillary Hyperhidrosis
The primary objective of this study is to demonstrate superiority of single treatment of GSK1358820 (hereinafter, referred to as BOTOX®) over placebo in terms of the efficacy of treatment with BOTOX® 50 U in each axilla (100 U in…
- Trial name
- NCT01128738
- Testing
- GSK1358820
- Where
- 14 sites in Japan
- Volunteers
- 152 people
- Sponsor
- GlaxoSmithKline
Hyperhidrosis
The Use of Microneedles With Topical Botulinum Toxin for Treatment of Palmar Hyperhidrosis
Hyperhidrosis or sweating of palms results from the overactivity of sweat glands and leads to psychosocial impairment with reduction in quality of life in those that are affected.
- Trial name
- NCT03203174
- Testing
- Microneedle, Botulinum Toxin Type A, Saline
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Health Care Utilization, Diet, Healthy
Assessment of the Rate of Oseointegration Surrounding Nano-coated Orthodontic Titanium Miniscrew
The current study was directed to evaluate rate of oseointegration surrounding nano-coated orthodontic titanium miniscrew.The current study will conduct on eighteen Egyptian males orthodontic patients for three months.
- Conditions
- Health Care Utilization, Diet, Healthy, Frey Syndrome
- Trial name
- NCT05898724
- Testing
- Blank group, Silver hydroxyapatite, Zinc oxide
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Axillary Hyperhidrosis
Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-301)
Hyperhidrosis is a disorder of abnormal excessive sweating. Primary hyperhidrosis (armpits, hands, and feet) affects approximately 4.8% of the US population and is believed to be caused by an overactive cholinergic response of…
- Trial name
- CardiganI (NCT03836287)
- Testing
- Sofpironium Bromide Gel, 15%, Vehicle
- Where
- 39 sites in United States
- Volunteers
- 350 people
- Sponsor
- Botanix Pharmaceuticals
Hyperhidrosis Primary Focal Axilla
Evaluate the Efficacy and Safety of MEDITOXIN in Treatment of Primary Axillary Hyperhidrosis
This study is intented to evaluate the efficacy and safety of MEDITOXIN compared to placebo in treatment of primary axillary hyperhidrosis.
- Trial name
- NCT03760198
- Testing
- Meditoxin
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Medy-Tox
Palmar Hyperhidrosis
A Study of Glycopyrronium Cloth, 2.4% in Patients With Palmar Hyperhidrosis
The objective of this study is to assess the efficacy and safety of glycopyrronium cloth, 2.4% when used to treat palmar hyperhidrosis.
- Trial name
- NCT03880266
- Testing
- Glycopyrronium cloth, 2.4%, Vehicle
- Where
- 7 sites in United States
- Volunteers
- 72 people
- Sponsor
- Journey Medical Corporation
Axillary Hyperhidrosis, Osmidrosis
Use of Oxybutynin to Treat Axillary Hyperhidrosis
The objective of this study was to evaluate the effectiveness and patient satisfaction with the use of oxybutynin at low doses for treating axillary hyperhidrosis in a large series of patients.
- Trial name
- NCT01118429
- Testing
- Oxybutynin
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Grupo de Cirurgia Vascular
Hyperhidrosis
A Study to Compare Oxybutynin to a Placebo in Women and the Effect on Plantar Hyperhidrosis
A study in which the experimental treatment procedure is compared to a standard (control) treatment, The use of oxybutynin in the late postoperative thoracic sympathectomy for women: 1.
- Trial name
- NCT01328015
- Testing
- Oxybutynin 5 mg pills
- Volunteers
- 32 people
- Sponsor
- Federal University of São Paulo
Amputation, Hyperhidrosis
Qbrexza Cloths for Hyperhidrosis of Amputation Sites
This is a Prospective, Double Blinded, Placebo Controlled, Randomized, Cross-over trial using Qbrexza Cloths to treat hyperhidrosis of amputation sites.
- Trial name
- NCT04924036
- Testing
- glycopyrronium cloths
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Utah