Clinical trials: Hyperbilirubinemia, Neonatal
Neonatal Hyperbilirubinemia
Neonatal Hyperbilirubinaemia in the Democratic Republic of Congo
Neonatal hyperbilirubinaemia (NH) is common among healthy neonates and normally resolves within a week. Untreated pathological hyperbilirubinaemia, however, can result in long-term neurological sequelae, which compromise…
- Trial name
- NCT03880591
- Where
- Democratic Republic of the Congo
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Procedural Pain, Neonatal Hyperbilirubinemia
The Effect of Kangaroo Care on Pain in Infants Receiving Phototherapy
This study aims to evaluate and compare the effects of two different kangaroo care (KC) models on pain management in neonates undergoing phototherapy.
- Trial name
- NCT07761689
- Testing
- Kangaroo Care, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Idiopathic Hyperbilirubinemia, Neonatal Hyperbilirubinemia
Glycerin Suppositories to Reduce Jaundice in Premature Infants
The purpose of this study is to find out if giving glycerin suppositories will help decrease the length of time premature infants need phototherapy.
- Conditions
- Idiopathic Hyperbilirubinemia, Neonatal Hyperbilirubinemia, Prematurity
- Trial name
- NCT01746511
- Testing
- Phototherapy, glycerin suppository
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Neonatal Jaundice
Role of Oral Zinc in Reducing Neonatal Indirect Hyperbilirubinemia
This study aimed to determine the role of oral zinc in reducing the neonatal indirect hyperbilirubinemia if used concomitant with the standard phototherapy
- Trial name
- NCT06227624
- Testing
- Oral zinc sulfate and standard phototherapy
- Where
- Egypt
- Volunteers
- 192 people
- Sponsor
- National Liver Institute, Egypt
Hyper Bilirubinemia, Phototherapy
The Effect of Abdominal Massage on Jaundice and Defecation in Newborn Babies
Hyperbilirubinemia is a common condition in term newborns and is often treated with phototherapy. It is thought that abdominal massage may increase bowel movements, thereby increasing the frequency of defecation and supporting…
- Conditions
- Hyper Bilirubinemia, Phototherapy, Jaundice, Neonatal
- Trial name
- NCT07388732
- Testing
- Massage once a day for 3 days., Massage twice a day for 3 days.
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kutahya Health Sciences University
Infant, Newborn, Jaundice
Prediction of Jaundice in Term Infants
The objective of this study was to describe total bilirubin production in healthy term infants as a means of understanding the differences in jaundice pigment production associated with various common clinical circumstances.
- Trial name
- NCT01203410
- Where
- 13 sites in United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Hyperbilirubinemia
The Effect of Acupressure on Hyperbilirubinemia in Newborns: A Randomized Controlled Trial
This study is a randomized controlled trial conducted to evaluate the effect of acupressure application on hyperbilirubinemia in newborns.
- Trial name
- NCT07409194
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Neonatal Hyperbilirubinemia
Transcutaneous Bilirubinometry and Phototherapy
A randomized Controlled trial comparing the use of transcutaneous bilirubinometry to serum bilirubin measurements (via blooddraws = standard care) in neonates born after a gestational age > 32 weeks and < 15 days of age treated…
- Trial name
- TRABIN (NCT04246229)
- Testing
- Transcutaneous bilirubinometry, Serum bilirubin
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Princess Amalia Children's Clinic
Hyperbilirubinemia
High Intensity Phototherapy: Double vs. Single
Intensive phototherapy in form of double light is used worldwide in the treatment of severe neonatal hyperbilirubinemia. It has been debated if there is an upper limit on the efficiency of phototherapy.
- Trial name
- NCT02805296
- Testing
- Light irradiance
- Volunteers
- 83 people
- Sponsor
- Aalborg University Hospital
Jaundice, Neonatal
Validation of an Innovative Neonatal Jaundice Detection System (Picterus) in Indonesia
The long-term goal of this project is to establish Picterus as a permanent tool to detect NNJ in the healthcare services of Indonesia.
- Trial name
- NCT05630495
- Testing
- Picterus Jaundice Pro
- Where
- 2 sites in Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Hyperbilirubinemia, Neonatal
The Incidence and Risk Factors of Neonatal Hyperbilirubinemia in Term and Late-preterm Chinese Infants
Thirteen hospitals in China will participate in the study, which aims to provide data on serum bilirubin levels in the first 168 hr after birth in term and late-preterm neonates, and estimate the incidence of severe neonatal…
- Trial name
- NCT01762189
- Testing
- Phototherapy
- Where
- 14 sites in China
- Volunteers
- 13,157 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Jaundice, Neonatal
The Effectiveness of Probiotics in Neonatal Jaundice
Hyperbilirubinemia is a prevalent problem in babies that necessitates medical attention. Probiotic administration as adjuvant therapy may have a positive impact on the pathological neonatal unconjugated hyperbilirubinemia.
- Trial name
- NCT06449508
- Testing
- Probiotic Formula
- Volunteers
- 44 people
- Sponsor
- Tanta University
Jaundice and Sepsis in Neonates
Ceftriaxone and Jaundice in Neonates
Ceftriaxone is an antibiotic often used for the management of sepsis. Neonates commonly have jaundice during the first postnatal week.
- Trial name
- CEFT (NCT03133637)
- Testing
- ceftriaxone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Rochester
Hyperbilirubinemia, Neonatal
Is Primiparity a Risk Factor for Neonatal Hyperbilirubinemia?
Neonatal hyperbilirubinemia elongates hospital stay and may require treatment. The investigators noticed that bilirubin levels were higher among infants of primipara mothers than among multipara mothers.
- Trial name
- NCT03329040
- Testing
- No Intervention.
- Where
- Israel
- Volunteers
- 4,369 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Neonatal Hyperbilirubinemia
Clinical and Developmental Outcomes of Babies Who Became Yellow in the First Month of Life
The Shoklo Malaria Research Unit (SMRU) provides care to refugees and migrant populations along the Thai-Burma border since 1986.
- Trial name
- NCT02927093
- Volunteers
- 78 people
- Sponsor
- University of Oxford
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Jaundice, Neonatal, Hyperbilirubinemia, Neonatal
Identification of Jaundice in Newborns Using Smartphones
Neonatal jaundice is a common and most often harmless condition. However, when unrecognized it can be fatal or cause serious brain injury. Three quarters of these deaths are estimated to occur in the poorest regions of the world.
- Trial name
- NCT04182555
- Testing
- Bilirubin estimates from Smartphone Application, Bilirubin concentration measured in standard blood samples, Bilirubin estimates from standard transcutaneous device
- Where
- 2 sites in Norway
- Volunteers
- 220 people
- Sponsor
- St. Olavs Hospital
Hyperbilirubinemia, Neonatal
The Predictors of the Neonatal Hyperbilirubinemia
The oxygen tension increases more than 3 times from fetus to neonate. The oxidant stress happens. And it will cause the destruction of RBC. So, we propose that the ROS may play an important role of neonatal hyperbilirubinemia.
- Trial name
- NCT00154999
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hyperbilirubinemia, Neonatal
TCB Self-Monitoring in Healthy Term and Near-Term Neonates
The goal of this observational study is to monitor the transcutaneous bilirubin (TCB) level in healthy near-term and full-term neonates from birth to 30 days of age across China.
- Trial name
- NCT06645158
- Testing
- Transcutaneous bilirubin level monitoring
- Where
- China
- Volunteers
- 220,950 people, healthy volunteers welcome
- Sponsor
- Neonatal-Infant Brain and Behavior Development Network