Clinical trials: Hydration Status
Fluid Balance
Effect of Adding Glycerol to Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest
The results of a prior study PEP-2311 suggested there was a positive dose-response effect of glycerol and sodium on fluid balance and fluid retention.
- Trial name
- NCT06654557
- Testing
- 0% carbohydrate electrolyte solution with glycerol beverage (Part 1 only), 0% carbohydrate electrolyte solution without glycerol beverage (Part 1 only), 1% carbohydrate electrolyte solution with glycerol beverage (Parts 1 and 2)
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Sodium Hyaluronate
Viscontour® Serum Med in Hydration of Facial Skin
The objective of this study is to confirm the clinical safety and efficacy of Viscontour® Serum Med in the hydration of facial tissue.
- Trial name
- NCT03494140
- Testing
- Viscontour® Serum Med
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- TRB Chemedica AG
Stress, Skin Imperfections
Effects Of A Probiotic Formulation On Stress and Skin Health in Younger Adult Females
The goal of this clinical trial is to test to efficacy of a probiotic blend on stress and skin appearance in young females. It is hypothesized that those taking the probiotic blend will have decreased levels of perceived stress…
- Conditions
- Stress, Skin Imperfections, Skin Fine Lines
- Trial name
- Cosmebiome (NCT06057883)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Hydration, Blood Glucose
Clinical Trial to Evaluate the Efficacy of a Sport Drink After High-intensity Aerobic Exercise
Although the general effectiveness of carbohydrate/electrolyte-based functional sports drinks on rehydration, recovery and sports performance has been widely demonstrated, there is controversy about the amounts, proportions and…
- Conditions
- Hydration, Blood Glucose, Sport Recovery, Microbiota
- Trial name
- NCT05352724
- Testing
- Hydration drink
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bioithas SL
Cystic Fibrosis
Trial to Assess the Safety, Tolerability and Pharmacokinetics of GS-9411 in Healthy Male Volunteers
The purpose of this study is to evaluate the safety and tolerability of escalating doses of GS-9411 in healthy male volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in…
- Trial name
- NCT00800579
- Testing
- GS-9411
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Dry Eye Disease, Cataract
Systane Hydration in Subjects Undergoing Cataract Surgery
The primary objective of this study is to demonstrate reduced corneal staining with use of Systane Hydration among subjects with dry eye disease (DED) undergoing routine cataract removal and monofocal intraocular lens (IOL)…
- Trial name
- NCT05056233
- Testing
- Systane Hydration lubricant eye drops
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Cosmetic Acne
Effect of a Facial Cream Containing Cannabidiol and Hemp Oil on Skin Hydration and Acne-prone Skin
This research seeks to evaluate the short (i.e., after single application) and long-term (i.e., after periodic application) hydrating effect of a topical preparation containing CBD and hemp oil on facial skin as well as the…
- Trial name
- Dahlia (NCT04045119)
- Testing
- Topical Moisturizer
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Avicanna Inc
Hydration Status
A Clinical Trial to Explore the Efficacy of Two Investigational Products on Post-Exercise Hydration in Recreationally Active Healthy Adults
The goal of this clinical trial is to explore the efficacy of two investigational products for promoting post-exercise hydration in recreationally active healthy adults.
- Trial name
- NCT07564661
- Testing
- Potassium15, Potassium10, Plain Water
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chobani
Skin Aging, Dry Skin
Human In Use Test of GINPI-HP-004 in Healthy Adults
The main objective of this study was to confirm skin acceptability of the product GINPI REF. GINPI BATCH: 10/06/2024 applied under normal use conditions in healthy female adult volunteers, under gynecological control, by means of…
- Trial name
- NCT07533474
- Testing
- Depigmentig cosmetic product
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- i+Med S.Coop.
Dry Eye
Systane® Hydration PF and Systane® Hydration Preserved
The purpose of this post-market clinical follow-up (PMCF) study is to assess the performance and safety of Systane Hydration Preservative Free (PF) in subjects experiencing dry eye symptoms (Group 1) and in contact lens (CL)…
- Trial name
- NCT05932238
- Testing
- Polyethylene glycol 400 and propylene glycol solution/drops - Preservative Free (PF), Polyethylene glycol 400 and propylene glycol solution/drops - Preserved
- Where
- 3 sites in Canada
- Volunteers
- 137 people
- Sponsor
- Alcon Research
Chronic Renal Failure
Initiative for Patient Outcomes in Dialysis - Peritoneal Dialysis (PD) (IPOD-PD Study)
The aim of the study is to asses the hydration status of incident peritoneal dialysis (PD) patients and its evolution over a period of four years, independent of the PD treatment modality (APD or CAPD) and the PD solution type.
- Trial name
- IPOD-PD (NCT01285726)
- Testing
- Non-interventional study
- Where
- 134 sites in Austria, Belgium and 26 more
- Volunteers
- 1,092 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Cystic Fibrosis, Mucociliary Clearance
A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS-9411 in Healthy Male Volunteers
The purpose of this study is to evaluate the safety and tolerability of escalating doses of GS-9411 in healthy male volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in…
- Conditions
- Cystic Fibrosis, Mucociliary Clearance, Airway Hydration
- Trial name
- NCT00951522
- Testing
- GS-9411
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Water Intake
A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes
A randomized, controlled trial evaluating the air up® drinking system's impact on hydration and health outcomes. Participants will use air up® with Peach, Orangeade, or unscented pods and their effects on drinking habits, and…
- Trial name
- NCT06290479
- Testing
- Air Up® Peach Pod, Air Up® Orangeade Pod
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- air up GmbH
Dehydration
Dehydration, Rehydration, and Blood Viscosity
The purpose of this study is to examine and compare the rehydration effect of Essentia Water, an electrolyzed high-pH bottled water, with industry-standard bottled water purified by reverse osmosis with minerals added, on (1)…
- Trial name
- NCT02118883
- Testing
- Essentia Water, Bottled water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essentia Water, LLC
Vaginismus, Vaginal Atrophy
Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women
Hyaluronic Acid is indicated for the relief of vaginal dryness, itching, and irritation, or the reduction of vaginal lubrication with prolonged hydration effects for up to 72 hours.
- Conditions
- Vaginismus, Vaginal Atrophy, Menopause
- Trial name
- NCT06564883
- Testing
- 0.20% sodium hyaluronate gel
- Volunteers
- 45 people
- Sponsor
- Biolab Sanus Farmaceutica
Acne Vulgaris, Hydration Acne
The Impact of Probiotics on Skin Hydration in Youth with Mild Acne
The goal of this clinical trials is to test the impact of probiotics on skin hydration in adolescents and young adults with mild acne.
- Trial name
- YSH (NCT05755256)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Spot Pigmented, Wrinkle
Clinical Study for the Efficacy Evaluation of a Food Supplement
The primary aim of this in vivo clinical study is to evaluate the depigmenting effect of an active ingredient incorporated into a food supplement through the evaluation of the melanin variation parameter, assessed with the…
- Trial name
- NCT06453837
- Testing
- Mentha Suaveolens extract incorporated into a food supplement
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Mibelle Group Biochemistry
Dry Skin
Efficacy Test on Skin Hydration and Skin Barrier Function
The effects of topically applied pyridoxine tri-isopalmitate (P-IP) which stimulates filaggrin synthesis in keratinocytes, on skin hydration and barrier function were examined.
- Trial name
- NCT01305057
- Testing
- Pyridoxine tri-isopalmitate
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmos Technical Center
Rosacea
Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application
This eight-hour kinetic regression clinical study was conducted to assess the ability of MetroGel® 1% to deliver moisture to facial skin after a single application.
- Trial name
- NCT00436527
- Testing
- Metronidazole gel 1%
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Galderma R&D
Sin Health, Skin Hydration
Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health
The purpose of the study was to evaluate the effectiveness of the äKwä 6-step skincare system by measuring skin moisture level, fine lines and wrinkles, porphyrin count, red spots, and red vasculature counts over a 30-day period.
- Conditions
- Sin Health, Skin Hydration, Skin Wrinkles, Skin Porphyrins
- Trial name
- NCT05476406
- Testing
- äKwä skincare system products, competitor products (control)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC