Clinical trials: Hydration
Cystic Fibrosis
Trial to Assess the Safety, Tolerability and Pharmacokinetics of GS-9411 in Healthy Male Volunteers
The purpose of this study is to evaluate the safety and tolerability of escalating doses of GS-9411 in healthy male volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in…
- Trial name
- NCT00800579
- Testing
- GS-9411
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Healthy
A Study of Two Facial Sunscreens to Assess Its Effect in Improving Hydration, Skin Barrier Function, and Skin Tone Uniformity Under Controlled and Normal Conditions of Use on the Face by Adult Participants
The purpose of this study is to evaluate the safety and efficacy of 02 facial sunscreens (investigational products [IPs]) under controlled and normal conditions of use on the face for 28 and 56 days, respectively.
- Trial name
- NCT05972434
- Testing
- Sunscreen A, Sunscreen B
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Chronic Renal Failure
PD-Improved Dialysis Efficiency With Adapted APD
The aim of this study is to observe the effect of adapted APD (aAPD) on maintenance and/or improvement of the hydration status of more than 250 PD patients, and to observe the tolerability of the therapy over a long period.
- Trial name
- PD-IDEA (NCT02470598)
- Testing
- Treatment with Adapted Automated Peritoneal Dialysis (aAPD)
- Where
- 50 sites in Czechia, Denmark and 4 more
- Volunteers
- 182 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Fluid Balance
Effects of Beverage Volume, Glycerol Concentration, and Sodium Concentration on Fluid Balance in Healthy Euhydrated Men and Women at Rest
The presence of certain ingredients such as sodium and glycerol can facilitate retention of the fluid consumed via renal water reabsorption.
- Trial name
- NCT06854471
- Testing
- Electrolyte solution without glycerol beverage 1, Electrolyte solution without glycerol beverage 2, Electrolyte solution without glycerol beverage 3
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Fainting, Presyncope
Evaluation of the Efficiency of Hydration by Isotonic Solution in the Prevent of the Fainting Whole Blood Donors
Blood donation is a generous act carried out by healthy male and female volunteer donors. The safety of blood donation in France is based on rigorous well documented biological and medical criteria, in particular concerning the…
- Conditions
- Fainting, Presyncope, Syncopal Episode
- Trial name
- EVASION (NCT02075099)
- Testing
- tensing exercises, No tensing exercises
- Where
- 2 sites in France
- Volunteers
- 4,825 people, healthy volunteers welcome
- Sponsor
- Etablissement Français du Sang
Ocular Physiology
Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process
This is a bilateral wear, dispensing, randomized, controlled, double-masked, 2-sequence × 2-period crossover study to evaluate ocular physiology following approximately one week of contact lens wear.
- Trial name
- NCT05427539
- Testing
- TEST LENS, CONTROL LENS
- Where
- 6 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Determine Sensitivity of Skin to Cetaphil Daily Advance Ultra Hydrating Lotion
Patch Test Skin Irritation/Sensitization of Cetaphil Daily Advance Ultra Hydration Lotion
Determine if Cetaphil Daily Advance Ultra Hydrating Lotion proves to be a contact sensitizer or irritant in certain individuals.
- Trial name
- NCT01885130
- Testing
- Cetaphil Daily Advance Ultra Hydrating Lotion
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Intermittent Water Intake
The Effects of Intermittent Water Consumption and Restriction on Serum Electrolyte Levels in Professional Football Players During Competition
Background: In sports requiring intense physical exertion, particularly in endurance-based disciplines such as football, exercise-induced fluid and electrolyte losses can have adverse effects on thermoregulation, cardiovascular…
- Trial name
- NCT07710092
- Testing
- Intermittent Plain Water Intake
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cardiac Arrhythmia
Measuring Hydration Levels of Healthy and Heart Failure Patients Before, During, and After an Electrophysiology (EP) Procedure
Subjects will be consented to wear the AleriTM sensor prior to, during, and after an Electrophysiology Procedure. During this time, the system will measure the following parameters from subjects: HR, temperature, saline…
- Trial name
- NCT04609683
- Testing
- AleriTM sensors
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Dry Eye
Evaluation of Clinical Outcomes After the Use of SYSTANE® HYDRATION
The purpose of this study is to compare SYSTANE® HYDRATION to Hyabak 0.15% based on total ocular surface staining scores (TOSS) at Day 42.
- Trial name
- NCT02470429
- Testing
- SYSTANE HYDRATION lubricant eye drops, Hyabak 0.15% eye drops, 0.9% saline eye drops
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Dehydration
Study of In-line Pressure Using Various Techniques of Subcutaneous Administration of Fluids Enabled by Human Recombinant Hyaluronidase (INFUSE-AT1A)
The purpose is to characterize the in-line pressure profiles associated with several infusion technique factors during subcutaneous (SC) infusion of Lactated Ringer's solution, preceded by recombinant human hyaluronidase…
- Trial name
- INFUSE-AT1A (NCT01116102)
- Testing
- Subcutaneous HYLENEX (recombinant human hyaluronidase) and Lactated Ringer's solution
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Water Intake
A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes
A randomized, controlled trial evaluating the air up® drinking system's impact on hydration and health outcomes. Participants will use air up® with Peach, Orangeade, or unscented pods and their effects on drinking habits, and…
- Trial name
- NCT06290479
- Testing
- Air Up® Peach Pod, Air Up® Orangeade Pod
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- air up GmbH
Healthy Volunteers
Evaluation of the Effect of the Dietary Supplement X34 on Skin Radiance of Healthy Volunteers With Dull Complexion
The main objective of this trial is to evaluate the effect of the daily dose of X34 dietary supplement on skin radiance (clinical assessment) for 8 weeks.
- Trial name
- NCT02347969
- Testing
- X34
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nutratech Conseils
Eczema
Impact of a Daily Application of an Omega-3 Monoglycerides Based Serum and Cream on the Skin Microbiota
This exploratory study aims to investigate the prebiotic potential of daily application of an omega-3 serum and cream to skin affected by eczema. The study will also collect data on any potential adverse effects of the products.
- Trial name
- COS-PBP-03 (NCT07583121)
- Testing
- Omega-3 monoglyceride based topical treatment
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- SCF Pharma
Aging, Wrinkle
Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health
Therefore, the present study is designed to contribute to the body of literature by investigating the effect of 12-weeks of lutein supplementation on multiple parameters of skin health and appearance in healthy women.
- Conditions
- Aging, Wrinkle, Skin Elasticity, Healthy
- Trial name
- NCT03769779
- Testing
- FloraGLO Lutein, Safflower Oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Heat Exposure, Exercise Performance
Effects of Creatine and Heat Exposure on Exercise Performance and Body Water Distribution
The goal of this clinical trial is to learn whether creatine supplementation changes how the body adapts to repeated exercise in the heat in healthy recreationally active adults and varsity athletes.
- Conditions
- Heat Exposure, Exercise Performance, Hydration, Body Fluid Compartments
- Trial name
- NCT07593014
- Testing
- Creatine Monohydrate
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Windsor
Skin Condition, Skin Hydration
Efficacy Test of a Moisturizing and Anti-aging Facial Mask
The objective of this study is to evaluate the effect of Moisturizing facial mask and Anti-aging facial mask on human skin condition improvement.
- Conditions
- Skin Condition, Skin Hydration, Anti Skin Aging
- Trial name
- NCT07622160
- Testing
- Hydrating Repairing Mask, Anti-aging Rejuvenating Mask
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.