Clinical trials: Human Milk
Human Milk Nutrient Reference Values
Establishing Global Reference Values for Human Milk
The primary purpose of the proposed research is to establish Reference Values (RVs) for micronutrients (MN) and macronutrients in human milk.
- Trial name
- MILQ (NCT03254329)
- Testing
- Assessment of human milk nutrient composition
- Where
- 4 sites in Bangladesh, Brazil and 2 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Infant, Premature, Diseases
Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants
The goal of this clinical trial is to learn if the multisensory early oral administration of human milk (M-MILK) intervention helps infants who are born younger than 32 weeks gestational age (very preterm infants).
- Trial name
- M-MILK RCT (NCT07216664)
- Testing
- Multisensory early oral administration of human milk
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Loyola University
Breastfeeding, Exclusive
Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development
The goal of this interventional study is to establish a whole food, avocado, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development.
- Trial name
- NCT06208085
- Testing
- Avocado
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Human Milk
The Influence of Storage Container and Defrost Process on Components in Breast Milk
Breast milk is best food for neonates and preterm infants. However many handling would be done if direct breastfeeding is not feasible, and it may result in nutrients change in human milk.
- Trial name
- NCT01932619
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Pediatric Obesity, Recruitment
The BEACH Interview Study- Pregnant and Breastfeeding Mothers
Interview pregnant and breastfeeding mothers in the Gainesville, FL area to optimize; clinical study recruitment and retention, patient-centered outcomes, and stool collection procedures.
- Trial name
- BEACH (NCT03036696)
- Testing
- Pregnant Mothers Interview, Breastfeeding Mothers Interview
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hypercholesterolemia
The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in Human
The purpose of this study is to determine whether YiLi Xinhuo Shuhua Milk is effective in reducing the serum cholesterol in human with hypercholesterolemia.
- Trial name
- NCT02475018
- Testing
- Milk fortified with plant sterol esters, Plain milk
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Premature Birth
Human Milk Fortifiers and Acid-Base Status
Double-blind randomized controlled trial to investigate the impact of two human milk fortifiers on acid-base status and longitudinal growth and weight gain in preterm infants.
- Trial name
- NCT00196482
- Testing
- changing of fortifier
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Medicine Greifswald
Nutrition, Healthy
The Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism
Dairy products provide macronutrients, vitamins, and minerals that are important for health and development. Despite this, many Canadians now eat fewer dairy products and are instead consuming more non-dairy alternatives, such as…
- Trial name
- NCT05820256
- Testing
- Milk Protein Isolate (MPI), Soy Protein Isolate (SPI)
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Preterm Birth, Breast Milk Expression
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
This study is a randomized trial comparing 2 methods of human milk fortification for preterm infants in the neonatal intensive care unit (NICU).
- Conditions
- Preterm Birth, Breast Milk Expression, Nutrition Disorder, Infant, Brain Development Abnormality
- Trial name
- NCT03977259
- Testing
- Individually targeted fortification
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Brigham and Women's Hospital
Premature Birth
Influence of Physical Treatments of Human Milk on the Kinetics of Gastric Lipolysis in Preterm Newborns
The optimization of newborns nutrition is a challenge especially for preterm newborns for whom nutrition plays a crucial part in cerebral and global development. Human milk is considered as the best food for newborns.
- Trial name
- ARCHILACT (NCT02112331)
- Testing
- Raw human milk, Pasteurized human milk, Pasteurized-homogenized human milk
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Rennes University Hospital
Allogeneic Hematopoietic Stem Cell Transplant Recipient, Hematopoietic and Lymphoid Cell Neoplasm
Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant
This phase I trial studies the side effects of human lysozyme goat milk in preventing graft versus host disease in patients with blood cancer undergoing a donor stem cell transplant.
- Trial name
- NCT04177004
- Testing
- Allogeneic Hematopoietic Stem Cell Transplantation, Cyclophosphamide, Etoposide
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- City of Hope Medical Center
Breastfeeding, Exclusive
Profile of Human Milk Oligosaccharides and FUT2 Polymorphism of Mothers in Indonesia
Human milk oligosaccharides (HMOs), the third most abundant constituent of breastmilk, are known to have beneficial effects on infant immunity. Maternal genetic polymorphisms cause HMO variability.
- Trial name
- NCT05156255
- Where
- Indonesia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
PreTerm Birth, Human Milk
Protein Balance and Body Composition in Preterm Infants
The adequacy of the quality of protein supply could influence the rate and the relative composition of weight gain in very low birth weight preterm infants.
- Trial name
- NCT03013374
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Healthy Growth
Growth and Tolerance Trial on Infant Formula With HMO
The aim of the study is to compare growth of healthy infants fed an infant formula supplemented with a human milk oligosaccharide to that of infants on standard formula.
- Trial name
- Stardust (NCT04066413)
- Testing
- Standard infant formula, Infant formula supplemented with HMO
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Breastfeeding, Human Milk
Comparison of Breast Milk Content in Mothers Using a Expressing Pump and Milking by Hand
The researchers planned this study to compare the effects of breast pumps, which are frequently used today, and manual milking after manual massage on the change in milk content when breast and breastfeeding problems develop.
- Trial name
- NCT05401123
- Testing
- milking pump
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Prematurity
Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial
The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging between 180 and 200 mL/kg/day on the body composition outcomes of moderately preterm infants born between 27…
- Trial name
- MAGIC (NCT06420531)
- Testing
- Human milk
- Where
- 4 sites in United States
- Volunteers
- 486 people
- Sponsor
- University of Alabama at Birmingham
Infectious Diseases, Healthy Subjects
Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
This single-center, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Infectious Diseases, Healthy Subjects, Respiratory Tract Infections, Sore Throat
- Trial name
- NCT01033799
- Testing
- Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), Non fermented dairy product (control)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Infant, Premature, Diseases
Adjustable Fortification of Human Milk Fed to Chinese Preterm Infants
This clinical trial will compare how the individualized and fortified human milk feeding will help a premature infant grow.
- Trial name
- NCT01731613
- Testing
- human milk fortifier
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Peking Union Medical College Hospital
Preterm Infant, Neonatal SEPSIS
Oropharyngeal Administration of Mother's Milk in Preterm Infants and Neonatal Infection
The protective effect of mother's milk and colostrum on oropharyngeal cavity is not achievable with gavage feeding. This may be increase the risk of colonization of the oropharyngeal cavity with pathogenic bacteria and subsequent…
- Conditions
- Preterm Infant, Neonatal SEPSIS, Neonatal Feeding Disorder
- Trial name
- OPAMM (NCT03513146)
- Testing
- Oropharyngeal Administration of Mother's Milk (OPAMM)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University Children Hospital
Fatty Acid Desaturases, Polymorphism, Single Nucleotide
Genetic Variants Modulate Association Between Dietary n-3 LCPUFAs and DHA Proportion in Breast Milk
DHA is important for the development of brain and retina in newborns. Considering that exclusive breast feeding for at least 4 ~6 months are globally recommended, plus it is well known that nutrient requirement is determined by…
- Conditions
- Fatty Acid Desaturases, Polymorphism, Single Nucleotide, Milk, Human
- Trial name
- NCT03842891
- Where
- Taiwan
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital