Clinical trials: Hot Flushes, open to volunteers
Postmenopausal Symptoms, Hot Flashes
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms…
- Trial name
- START (NCT06030388)
- Testing
- Strength training, High-intensity aerobic training
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Linkoeping University
Menopause, Menopausal Symptoms
A Clinical Trial to Evaluate the Effects of A Supplement on Symptoms of Menopause and Overall Well-being
This study evaluates the effects of Primal Harvest's Primal Meno+ supplement on symptoms of menopause and overall well-being in females aged 40-60 who are currently menopausal and experiencing at least two menopausal symptoms.
- Conditions
- Menopause, Menopausal Symptoms, Hot Flashes, Night Sweats
- Trial name
- NCT07903480
- Testing
- Primal Meno+ Supplement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Primal Harvest, LLC
Menopause Hot Flashes
Fezolinetant and Vascular Health and Brain Health
The goal of this clinical trial is to learn whether a study drug called fezolinetant impacts cardiovascular and cognitive health in women who have moderate to severe menopausal hot flashes and night sweats.
- Trial name
- FAVES-B (NCT07606664)
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rebecca Thurston
Accupuncture, Prostate Cancer
Comparing Acupuncture vs. Sham Acupuncture for the Management of Hot Flashes in Prostate Cancer Patients Receiving Hormone Therapy
This study is evaluating whether acupuncture may help reduce hot flashes in men receiving hormone therapy for prostate cancer. Hot flashes are a common side effect of androgen deprivation therapy (ADT) and may negatively affect…
- Conditions
- Accupuncture, Prostate Cancer, Hormone Therapy, Hot Flashes
- Trial name
- NCT07594002
- Testing
- Real Acupuncture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kentucky
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Hot Flashes
A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause
This study is for women in India who are going through menopause. They have symptoms including hot flashes and night sweats (also known as vasomotor symptoms or VMS).
- Trial name
- NCT07829653
- Testing
- Fezolinetant
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Prostate Cancer, Hot Flashes
A Feasibility Study of Biometric Measurements Via Wearable Smart Watch Technology for Evaluation of Vasomotor Symptoms in Patients Treated With Androgen Deprivation Therapy for Prostate Cancer (Prostate 007)
The purpose of this study is to find out if patients with prostate cancer who have vasomotor symptoms, commonly called hot flashes, from their Androgen Deprivation Therapy (ADT) will consistently wear a smartwatch device to track…
- Trial name
- BioWEAR (NCT07535541)
- Testing
- VMS logging
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Virginia
Hot Flashes, Breast Cancer
Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.
This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation…
- Conditions
- Hot Flashes, Breast Cancer, Acupuncture
- Trial name
- NCT05460819
- Testing
- Acupuncture treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Perimenopause, Menopause
The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.
The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women.
- Trial name
- NCT07135232
- Testing
- Sarmentosin - L- theanine, Resistance Training
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Menopause, Hot Flashes
Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women
The purpose of this research is to understand how training the muscles used for breathing (inhalation) affects menopausal hot flashes, sympathetic nerve activity and sleep.
- Conditions
- Menopause, Hot Flashes, Blood Pressure Regulation
- Trial name
- NCT06743269
- Testing
- High-Resistance Inspiratory Muscle Strength Training, Low-Resistance Inspiratory Muscle Strength Training, POWERbreathe K3 device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer, Hot Flash Due to Medication
REDucing Hot FLASHes in Women Using Endocrine Therapy.
The goal of this randomized intrapatient cross-over study is to assess the efficacy of oxybutynin versus venlafaxine in reducing hot flashes in women using endocrine therapy after breast cancer.
- Trial name
- REDFLASH (NCT06106529)
- Testing
- Oxybutynin, Venlafaxine
- Where
- Netherlands
- Volunteers
- 260 people
- Sponsor
- Reinier de Graaf Groep
Menopause Hot Flashes
Thermoregulatory Physiology of Menopausal Hot Flashes
This study is evaluating the effects of cooling on menopausal hot flashes in midlife women. Precise targeted cooling is provided to areas of the skin when a hot flash occurs.
- Trial name
- NCT07824648
- Testing
- Intervention C (Targeted skin cooling), Intervention B (Ambient cooling), Intervention A (Room temperature)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- SRI International
Menopause, Menopausal Vasomotor Symptoms
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms
Given the impact that hot flashes and night sweats can have on daily life during the menopausal transition, our team has developed a therapist-guided online cognitive behavioural therapy (CBT)- based program to help individuals…
- Trial name
- ICBT-Meno-VS (NCT07873177)
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Hot Flashes, Sleep
Impact of Cooling Mats on Vasomotor Symptoms in Patients Receiving Endocrine Therapy
This research study will investigate whether using a non-drug option, like a cooling mat, made of temperature-regulating materials, can help relieve the discomfort of hot flushes and/or night sweats for people receiving hormone…
- Conditions
- Hot Flashes, Sleep, Hormonal, Cancer
- Trial name
- COOLVAS (NCT07422727)
- Testing
- Cooling Gel Mats
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Sligo General Hospital
Menopause
Satavari and Ashoka for Menopause (SAM) Study
This 12-week randomized, placebo-controlled clinical trial will evaluate the efficacy and safety of a daily oral supplement containing Ashoka Bark and Shatavari in women experiencing menopausal symptoms.
- Trial name
- SAM (NCT07861295)
- Testing
- Ashoka Bark and Shatavari
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vidya USA Corporation
Hot Flashes, Breast Cancer
Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients
Hot flashes present a considerable problem for many breast cancer patients; these symptoms may be intensified by hormonal therapies, such as aromatase inhibitors or tamoxifen.
- Trial name
- NCT01530373
- Testing
- solifenacin, Clonidine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Arkansas
Menopause, Hot Flashes
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
This study will evaluate whether an 8-week course of a standardized herbal extract containing Shatavari and natural bio-enhancer ingredients can reduce menopausal symptoms in post-menopausal women.
- Trial name
- RENEW (NCT07834463)
- Testing
- Shatavari (Asparagus racemosus) Extract
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- India Glycols Ltd
Menopause, Menopause Hot Flashes
Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women
The menopausal transition is associated with significant hormonal changes that negatively impact many women's quality of life. Vasomotor symptoms, sleep disturbances, mood changes, and genitourinary symptoms are frequently…
- Conditions
- Menopause, Menopause Hot Flashes, Overweight , Obesity, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07822230
- Testing
- Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population in printed material and 5 in-person and virtual meetings, Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population only in printed material
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Menopause-related Hot Flashes
Finding Links Between Hot flASHes and CardioVascular Disease
The goal of this clinical trial is to learn if neurokinin-1/neurokinin-3 receptor antagonist elinzanetant improves blood vessel health in women with moderate to severe hot flashes.
- Trial name
- FLASH-CV: (NCT07077395)
- Testing
- elinzanetant - reference formulation
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Hot Flashes, Menopause
Hot Flashes and Neurovascular Function in Women
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship.
- Conditions
- Hot Flashes, Menopause, Vasomotor System; Labile
- Trial name
- NCT05193968
- Testing
- Sympathoexcitatory stressors, Sodium Nitroprusside, Acetylcholine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic