Clinical trials: Hot Flashes
Hot Flashes, Menopause
Climacteric Therapy With Applied Relaxation Using InterNet
The aim is to evaluate effects of internet-based applied relaxation (a simplified version of cognitive behavioral therapy) for women with menopausal symptoms mainly vasomotoric symptom (VMS), i.e. hot flashes and sweating.
- Trial name
- CARIN (NCT01245907)
- Testing
- Applied relaxation
- Where
- Sweden
- Volunteers
- 46 people
- Sponsor
- Mats Hammar
Menopause
Symptom Monitoring and Menopausal Symptoms
A recent systematic review suggested that symptom monitoring can result in reductions in menopausal symptoms and improvements in health-related behaviours.
- Trial name
- NCT05603234
- Testing
- Symptom Monitoring
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Hot Flashes, Menopause
MsFLASH-02: Interventions for Relief of Menopausal Symptoms: A 3-by-2 Factorial Design Examining Yoga, Exercise, and Omega-3 Supplementation
This study is the second clinical trial to be conducted by the Menopause Strategies - Finding Lasting Answers for Symptoms and Health (MsFLASH) research network, a group of investigators conducting clinical trials designed to…
- Conditions
- Hot Flashes, Menopause, Vasomotor Symptoms
- Trial name
- NCT01178892
- Testing
- Omega-3, Yoga, Exercise
- Where
- 3 sites in United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Perimenopause
Acupuncture for Relieving Perimenopausal Symptoms
The purpose of this study is to determine whether acupuncture is effective for relieving perimenopausal symptoms.
- Trial name
- NCT01933204
- Testing
- Acupuncture, Climen 21 Tablets
- Where
- 2 sites in China
- Volunteers
- 220 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Hot Flashes, Breast Cancer
Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients
Hot flashes present a considerable problem for many breast cancer patients; these symptoms may be intensified by hormonal therapies, such as aromatase inhibitors or tamoxifen.
- Trial name
- NCT01530373
- Testing
- solifenacin, Clonidine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Arkansas
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Menopause, Hot Flashes
Black Cohosh Extract in Postmenopausal Breast Health
The purpose of the study is to determine if black cohosh extract (BCE) administration in symptomatic postmenopausal women results in estrogenic stimulation of the breast, as determined by estradiol, pS2, FSH, LH, and PSA levels…
- Trial name
- NCT00064831
- Testing
- Black Cohosh Extract (BCE)
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Postmenopausal Symptoms, Hot Flashes
WHAT (Women, Hot-flashes, Activity, Trial) - Physical Activity for Treatment of Hot Flushes Among Postmenopausal Women
More than 60 % of women experience hot-flashes during postmenopausal and 20 % have serious symptoms. Use of combined estrogen/progesterone therapy reduces hot-flashes effectively.
- Trial name
- WHAT (NCT01282320)
- Testing
- Physical activity intervention program
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Hot Flashes
A Clinical Trial Assessing Safety of MF101 for Hot Flushes
This Phase 1, open label, randomized clinical trial will enroll 40 generally healthy, postmenopausal women aged 40-65 years old. Women will be randomized to one of two oral doses of MF101 for 4 weeks.
- Trial name
- NCT01300078
- Testing
- MF101
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bionovo
Menopause
Effects of a Seven-day BASIS™ Supplementation on Menopausal Syndromes and Measurements of the Urinary Vitamin B3 and Estradiol Levels in Pre-, Peri- and Post-menopause
The purpose of this study is to determine whether a short supplementation (7days) with BASIS™ increases the natural production of estradiol, measured in urinary waste.
- Trial name
- NCT04841499
- Testing
- BASIS™ (Crystalline Nicotinamide Riboside 250mg and Pterostilbene 50mg)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Prostate Carcinoma
Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer
This phase II trial compares the effect of oxybutynin versus placebo for reducing hot flashes in men receiving androgen deprivation (hormone) therapy for the treatment of prostate cancer .
- Trial name
- NCT04600336
- Testing
- Oxybutynin Chloride, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 103 sites in United States
- Volunteers
- 88 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hot Flashes
Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause
The primary purpose of this study is to determine if PD-0299685 is effective and safe in the treatment of vasomotor symptoms (hot flashes / flushes) associated with menopause.
- Trial name
- NCT00314964
- Testing
- PD-0299685
- Where
- 80 sites in United States, Australia and 4 more
- Volunteers
- 527 people
- Sponsor
- Pfizer
Menopause, Hot Flashes
Validation of an Objective Instrument to Measure Hot Flashes During Menopause
The overarching aim of this study is to assess the validity of the iButton®, a dual temperature and humidity sensing device (DS1923; Maxim IntegratedTM), as an objective method to assess hot flash incidence and dynamics in both a…
- Trial name
- FLAME (NCT03642119)
- Testing
- iButton®
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Breast Cancer, Cancer Survivor
Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer
RATIONALE: Magnesium oxide may help relieve hot flashes in women with cancer. PURPOSE: This phase II trial is studying how well magnesium oxide works in treating hot flashes in menopausal women with cancer.
- Conditions
- Breast Cancer, Cancer Survivor, Hot Flashes, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01008904
- Testing
- magnesium oxide, questionnaire administration, quality-of-life assessment
- Volunteers
- 31 people
- Sponsor
- Virginia Commonwealth University
Hot Flashes, Stress
Mindfulness Based Stress Reduction for Hot Flashes
Stress appears to be related to hot flash frequency and intensity, and the degree of distress that women experience from their hot flashes appears to be related to their coping resources.
- Trial name
- NCT00317304
- Testing
- Mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Vasomotor Symptoms, Hot Flashes
Low-dose Hormone Therapy for Relief of Vasomotor Symptoms
The purpose of this study is to determine the lowest effective dose of the study drug for the relief of moderate to severe vasomotor symptoms in postmenopausal women for 12 weeks.
- Trial name
- NCT00446199
- Testing
- 0.5mg DRSP / 0.5mg E2 (BAY86-4891), 0.25mg DRSP / 0.5mg E2 (BAY86-4891), Estradiol (E2 0.3mg)
- Where
- 76 sites in United States
- Volunteers
- 735 people
- Sponsor
- Bayer
Hot Flashes, Menopause Surgical
Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers
Risk-reducing surgery with salpingo-oophorectomy (RRSO) is the standard recommended treatment for all female carriers of BRCA genes 1 and 2.
- Trial name
- BRCA (NCT05331209)
- Testing
- Acupuncture, Acupuncture-Acupressure
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Hot Flashes
A Study to Confirm if Fezolinetant Helps to Reduce Hot Flashes in Indian Women Going Through Menopause
This study is for women in India who are going through menopause. They have symptoms including hot flashes and night sweats (also known as vasomotor symptoms or VMS).
- Trial name
- NCT07829653
- Testing
- Fezolinetant
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc
Hot Flashes
A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
One of the standard treatments for women with breast cancer is hormone therapy, but this treatment can cause hot flashes. Hormone replacement therapy, or HRT, is most often prescribed for hot flashes for women in menopause but…
- Trial name
- NCT06440967
- Testing
- Fezolinetant, Tamoxifen, Aromatase inhibitor
- Where
- 110 sites in Canada, Czechia and 9 more
- Volunteers
- 982 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Hot Flashes, Menopause
Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms
This Phase II study, a follow-up to a Phase I trial in normal volunteers, will determine the efficacy of black cohosh and red clover for the relief of menopausal symptoms.
- Trial name
- NCT00066144
- Testing
- Cimicifuga racemosa, Trifolium pratense, Black cohosh
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)