Clinical trials: Hospitalizations
Pneumonia, Pneumococcal Infections
Serotype Distribution in Hospitalized Adult With Pneumococcal Community Acquired Pneumonia in France
CAP'Hospi is an observational, multicentric study in France which primary objective is to describe the proportion of Community Acquired Pneumonia due to serotypes included in PCV20 among adults hospitalized for CAP
- Conditions
- Pneumonia, Pneumococcal Infections, Community-acquired Pneumonia
- Trial name
- CAP'Hospi (NCT05380193)
- Where
- 5 sites in France
- Volunteers
- 1,017 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Head and Neck Cancer
Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients
The goal of this research study is to learn if home-use of devices to identify dehydration risk, when added to standard care, will help to lower hospitalizations and emergency room visits (and related costs) in patients with head…
- Trial name
- NCT02253238
- Testing
- Quality of Life Survey, Health Management Surveys, Monitoring Devices
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- M.D. Anderson Cancer Center
Coinfection
Effects of Viral and Bacterial Co-infections in Otherwise Healthy Children Hospitalized in Pediatric Department
Co-occurence of multiple pathogens in children is a known phenomenon, however the potential effect on the probability to develop a disease and on its severity, as well as the relationships between them, has not been studied…
- Trial name
- NCT02325102
- Testing
- No intervention
- Volunteers
- 400 people
- Sponsor
- Hillel Yaffe Medical Center
Liver Dysfunction, Morbidity
Von Willebrand Factor to Predict Postoperative Outcome
vWF is stored in weibel-palade-bodies of endothelial cells as well as alpha-granula of platelets and is released upon their activation.
- Conditions
- Liver Dysfunction, Morbidity, Mortality, Hospitalisation
- Trial name
- NCT02118545
- Where
- 4 sites in Austria, Switzerland
- Volunteers
- 133 people
- Sponsor
- Medical University of Vienna
Hypokalemia
Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl
evaluate efficacy and safety of IV administration of potassium chloride (KCl) plus 0.9%NaCl compare with KCl plus half-strength normal saline solution (0.45%NaCl) in correcting hypokalemia
- Trial name
- NCT02721095
- Testing
- KCl plus 0.9%NaCl, KCl plus 0.45%NaCl
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Alcohol Consumption
Health Behavior Change for Hospitalized Veterans
Veterans drink, binge drink, and drive under the influence of alcohol at higher rates than non-Veterans do. Addressing alcohol misuse, the range of alcohol consumption from risky drinking to alcohol abuse and alcoholism, is a…
- Trial name
- NCT01602172
- Testing
- Brief Alcohol Intervention, Lifestyle brochures
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- VA Office of Research and Development
Heart Failure, Renal Dysfunction
Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction
The purpose of the study is to determine if low doses of BNP can improve renal function in people with chronic heart failure with renal dysfunction, also to determine whether Sildenafil assists with improvement.
- Trial name
- Aim 3 BNP/PDEV (NCT00972569)
- Testing
- BNP and PDE-V, BNP
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
COVID-19, SARS-CoV2 Infection
International Sites: Novel Experimental COVID-19 Therapies Affecting Host Response
The overarching goal of the Master Protocol is to find effective strategies for inpatient management of patients with COVID-19. Therapeutic goals for patients hospitalized for COVID-19 include hastening recovery and preventing…
- Conditions
- COVID-19, SARS-CoV2 Infection, Coronavirus Infection
- Trial name
- NECTAR (NCT05593770)
- Testing
- Fostamatinib
- Where
- 21 sites in Brazil, Germany and 3 more
- Volunteers
- 28 people
- Sponsor
- NEAT ID Foundation
Deep Vein Thrombosis, Pulmonary Embolism
Registry of Hospitalized Patients Treated With Fondaparinux
Registry of Hospitalized patients at Brigham and Women's Hospital treated with Fondaparinux
- Trial name
- NCT00549705
- Volunteers
- 220 people
- Sponsor
- Brigham and Women's Hospital
Malnutrition
Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients
Newly admitted patients will be screened for risk of malnutrition. Patients will receive either the feeding protocol or current oral nutrition supplement (ONS) practice, pending location.
- Trial name
- NCT02262429
- Testing
- ONS QIP, ONS Standard Feeding
- Where
- 4 sites in United States
- Volunteers
- 2,386 people
- Sponsor
- Abbott Nutrition
Heart Failure
Home-Based Fluid Status Monitoring in Heart Failure Patients
This is a prospective, multi-center, single-arm study enrolling adult patients who have been hospitalized for heart failure and subsequently discharged.
- Trial name
- NCT04013373
- Testing
- SOZO Bioimpedance Spectroscopy Device
- Where
- 15 sites in United States
- Volunteers
- 92 people
- Sponsor
- ImpediMed Limited
Covid19, COVID-19 Pneumonia
Efficacy and Safety of Antimicrobial Stewardship Intervention in Hospitalized COVID-19 Patients (COVASP)
COVID-19 is respiratory disease caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2), a novel coronavirus which has spread rapidly across the world with over 149.9 million laboratory confirmed cases and over 3.1…
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Lower Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- COVASP (NCT04896866)
- Testing
- Antimicrobial stewardship prospective audit and feedback
- Where
- 3 sites in Canada
- Volunteers
- 833 people
- Sponsor
- University of Alberta
Delirium
Brief Delirium Assessments in Non-Intensive Care Unit (ICU) Patients
Delirium is an acute confusional state characterized by fluctuating mental status, inattention, and either disorganized thinking or an altered level of consciousness.
- Trial name
- NCT01162369
- Where
- 2 sites in United States
- Sponsor
- Vanderbilt University Medical Center
Dementia
Adverse Drug Reactions in Older Subjects
Objective: To identify risk factors for the occurrence of adverse drug reactions (ADRs) based on geriatric evaluation. Design: Longitudinal prospective study from May 2010 to November 2011.
- Trial name
- RiskofADR (NCT03623542)
- Where
- France
- Volunteers
- 293 people
- Sponsor
- CHU de Reims
Heart Failure
Animal-Assisted Therapy for Hospitalized Heart Failure Patients
Effects of complementary therapies on heart failure, a leading cause of hospitalization, are unknown. Animal-assisted therapy improves physiological and psychosocial variables in healthy and hypertensive subjects.
- Trial name
- NCT00391456
- Testing
- Animal-assisted Therapy
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of California, Los Angeles
Nutritional Status
The Effect of When Medication is Taken on Nutritional Status in Hospitalized Patients Older Than 65 Years
Polypathology in elderly subjects requires polypharmacy but even though the efficacy of a medication and digestive tolerance are ensured, the medication can be taken a long time from meals to reduce its side-effects.
- Trial name
- MEDICANUT2 (NCT02894827)
- Testing
- Blood sample, Flow cytometry, western blot
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hospitalization
Vital Signs Reduction Study
Overnight vital signs are typically done every four hours on pediatric acute care units, despite limited evidence supporting the efficacy of this practice.
- Trial name
- NCT06865781
- Testing
- Forgone overnight vital signs
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Intermountain Health Care, Inc.
Sepsis, Septic Shock
ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock
Immunonutrition in intensive care has not yet demonstrated a beneficial effect on organ failure, the acquisition of nosocomial infections, or mortality.
- Trial name
- ICITRU (NCT04513288)
- Testing
- Experimental treatment L-citrulline (Protéocit®)
- Where
- 5 sites in France
- Volunteers
- 130 people
- Sponsor
- Rennes University Hospital
Schizophrenia, Schizophrenia; Psychosis
A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)
This is a Phase 3, randomized, double-blind, parallel-group, placebo-controlled, multicenter inpatient study to examine the efficacy and safety of KarXT in adult subjects who are acutely psychotic with a Diagnostic and…
- Trial name
- NCT04659161
- Testing
- Xanomeline and Trospium Chloride Capsules
- Where
- 22 sites in United States
- Volunteers
- 252 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Health Insurance
Experimental Study to Assess Interventions Aimed at Improving the Equity Impact of Community-Based Health Insurance
The purpose of this study is to assesses interventions aimed at improving the distributional impact of a community based health insurance scheme in rural India.
- Trial name
- NCT00421629
- Testing
- After-sales service and supportive supervision (AfterSS), Prospective reimbursement (PR), Both (AfterSS and PR)
- Where
- India
- Volunteers
- 688 people
- Sponsor
- London School of Hygiene and Tropical Medicine