Clinical trials: Hoarseness
Functional Dysphonia
A Trial of Transcranial Magnetic Stimulation in the Treatment of Functional Dyspepsia
The goal of this clinical trial is to learn if theta burst stimulation (TBS), a form of Transcranial Magnetic Stimulation (TMS), can treat functional dyspepsia (FD) and compare its effectiveness against conventional drug…
- Trial name
- NCT06559748
- Testing
- transcranial magnetic thetaburst stimulation （TBS）
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Deglutition Disorder, Healthy
Electrical Muscle Stimulation to Aid Swallowing in Dysphagia
The purpose of this study is to determine the feasibility of using extrinsic laryngeal muscle stimulation to elevate the larynx in a manner similar to that which occurs during normal swallowing.
- Trial name
- NCT00001936
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dysphonia
Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Despite the considerable use of oral steroids in the regular management of benign vocal fold lesions there is little evidence base in the literature.
- Trial name
- AAO (NCT02286960)
- Testing
- Steroid, Lactose Pills
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application
Deep Brain Stimulation (DBS) is a neurosurgical procedure used to treat tremors, and dystonia. This study will enroll people who have a form of focal dystonia that affects their vocal cords called Adductor Laryngeal dystonia…
- Trial name
- NCT05506085
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Indiana University
Cough, Vocal Cord Atrophy
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who are undergoing superior laryngeal nerve block, injection laryngoplasty…
- Conditions
- Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis
- Trial name
- NCT06579989
- Testing
- Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Voice and Resonance Disorders, Vocal Fold Polyp
Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Current semi-occluded vocal tract therapies limit the type of vocalizations that can be produced to single vowels, which does not promote learning of the healthy voice behavior in connected speech or generalization to…
- Conditions
- Voice and Resonance Disorders, Vocal Fold Polyp, Vocal Cord Cyst, Vocal Cord Polyp
- Trial name
- NCT03410797
- Testing
- Inclusion of semi-occluded mask in voice therapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Jacqueline Gartner-Schmidt
Myasthenia Gravis, Fatigue
Capturing Key MG-symptoms Using Smartphone Recordings.
This study will make use of a cross-sectional design of MG patients and non-MG participants to quantitatively assess key MG symptoms, and to explore the applicability of machine learning algorithms to their measurement.
- Trial name
- CAPTURE - MG (NCT06743490)
- Where
- 2 sites in Netherlands
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Respiration Disorders, Swallowing Disorder
Artificial Intelligence in Diagnosing Dysphagia Patients
In this prospective study we extracted acoustic parameters using PRAAT from patient's attempt to phonate during the clinical evaluation using a digital smart device.
- Conditions
- Respiration Disorders, Swallowing Disorder, Phonation Disorder, Stroke
- Trial name
- NCT05098808
- Testing
- Acoustic features (from signals obtained during phonation)
- Where
- South Korea
- Volunteers
- 449 people
- Sponsor
- The Catholic University of Korea
Muscle Tension Dysphonia
The Effects of Respiratory Training on Voice
Primary muscle tension dysphonia is a voice disorder that involves excessive and poorly coordinated muscle activity affecting multiple subsystems that are involved in speech production, in the absence of structural or neurologic…
- Trial name
- NCT04710862
- Testing
- Breathing training without a device, Breathing training with a device
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Syracuse University
Anesthesia Intubation Complication, Tracheal Disease
The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Sore throat is one of most frequent complaints related to general anesthesia with tracheal intubation. Although sore throat is regarded as a minor and short-lasting discomfort after surgery, its incidence and intensity in high…
- Trial name
- NCT02039427
- Testing
- Ketorolac, Dexamethasone
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yeungnam University College of Medicine
Laryngeal Dystonia, Spasmodic Dysphonia
Cortical Silent Period in Laryngeal Dystonia
The goal of this observational study is to evaluate the cortical silent period (cSP) in cricothyroid muscle (CT) in laryngeal dystonia and control healthy subjects.
- Trial name
- cSPDystonia (NCT05580302)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- Croatia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Sore Throat, Dysphagia
LMA Cuff Pressure and LMA-induced Complications
The purpose of this study is to determine if using 20 mL B.Braun syringes to inflate LMAs and allowing them to recoil will put the pressure of the LMA cuff within the safety range.
- Conditions
- Sore Throat, Dysphagia, Dysphonia
- Trial name
- NCT01385969
- Testing
- Standard inflation of LMA cuff, Pressure check with syringe recoil, Pressure check by pressure transducer
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Mayo Clinic
Adductor Spasmodic Dysphonia, Abductor Spastic Dysphonia
Laryngeal Vibro-tactile Stimulation as a Non-invasive Symptomatic Treatment for Spasmodic Dysphonia
The general aim of the research is to provide scientific evidence that vibro-tactile stimulation (VTS) represents a non-invasive form of neuromodulation that can induce measurable improvements in the speech of patients with…
- Conditions
- Adductor Spasmodic Dysphonia, Abductor Spastic Dysphonia, Laryngeal Dystonia
- Trial name
- NCT05467228
- Testing
- vibro-tactile stimulation (VTS)
- Where
- United States
- Sponsor
- University of Minnesota
Functional Dysphonia, Voice Disorders
Dysphonia, Distress, and Perceived Control: Technology Based Assessment and Intervention
The purpose of this study is to pilot test a version of the intervention that has been tailored for participants with dysphonia.
- Conditions
- Functional Dysphonia, Voice Disorders, Dysphonia
- Trial name
- NCT03576365
- Testing
- VOICE Intervention Arm, Information-Only Arm
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Neck Pain, Voice Change
Stabilization Training, Voice And Neck Pain
This randomized controlled trial investigated the effects of cervical stabilization exercises on head posture, pain, functional status, and voicing efficiency in patients with nonspecific chronic neck pain.
- Trial name
- NCT07401576
- Testing
- cervical stabilization exercises applied
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Postoperative Sore Throat, Cough, Hoarseness, Thyroid and Parathyroid Surgery
Sore Throat After Open Neck Elective Surgery
This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough…
- Trial name
- STONES (NCT07124650)
- Testing
- Hydrocortisone Acetate 1% Ointment, Lidocaine hydrochloride 0,05% with chlorhexidine
- Where
- Russia
- Volunteers
- 764 people
- Sponsor
- Saint Petersburg State University, Russia
Hoarseness, Dysphonia
A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC).
- Conditions
- Hoarseness, Dysphonia, Aphonia, Vocal Fold Scar
- Trial name
- NCT04290182
- Testing
- MSC-KI-PL-204
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska University Hospital
Sore Throat
Effect of Intraoperative Neuromuscular Blockade on Postoperative Sore Throat and Hoarseness
Investigators assess and compare postoperative sore throat and hoarseness in the group using the muscle relaxant and not using it during the operation.
- Trial name
- NCT03397797
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- SMG-SNU Boramae Medical Center
Hoarseness, Intubation
Rigid Video Stylet Vs Conventional Lightwand Intubation
Lightwand is a useful alternative device for intubation but scooping movement can induce damage and microbleeding of oral mucosa, postoperative hoarseness,sore throat.
- Conditions
- Hoarseness, Intubation, Sorethroat
- Trial name
- Optiscope (NCT02073786)
- Testing
- Conventional lightwand intubation, Rigid video stylet
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Hospital
Voice Disorders, Gastroesophageal Reflux
Quantifying Effects of Treatment of Pediatric Dysphonia
The diagnosis and management of childhood dysphonia is a significant clinical problem; however, there have been few studies aimed at defining standard assessment methods for pediatric dysphonia.
- Trial name
- NCT00237679
- Testing
- Neuromuscular Electrical Stimulation, Unstimulated
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison