Clinical trials: Herniated Disc
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Degenerative Disc Disease, DDD
Biologic Injection For Adults With Lumbar Disc Herniation
The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar
- Trial name
- BMAC (NCT07386548)
- Testing
- Bone Marrow Aspirate Concentrate (BMAC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Weill Medical College of Cornell University
Lumbar Disc Herniation
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation
Lumbar disc herniation compressed the nerve cause pain, numbness, weak legs called sciatica, which seriously decrease the quality of life and work efficiency.
- Trial name
- NCT05330806
- Testing
- Collagenase chemonucleolysis, Percutaneous endoscopic lumbar discectomy (PELD)
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shenzhen People's Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Dorsal Root Ganglion Intervention Treatments
This study applies 3D-printed customized guide plate in assisting the accurate puncture in transforaminal epidural steroid injection (TFESI) combined with pulsed radiofrequency (PRF) treatment.
- Trial name
- NCT05403775
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Cervical Disc Herniation
Functional Outcome After Surgery for Cervical Disc Prolapse
Cervical disc herniation (CDH) is the result of the displacement of the nucleus pulposus of the intervertebral disc, which may result in impingement of the traversing nerves as they exit the neural foramen or directly compressing…
- Trial name
- NCT06857643
- Volunteers
- 30 people
- Sponsor
- Assiut University
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Proprio Spine Measurement Tool
This study will prospectively collect data to evaluate the effectiveness of a novel intraoperative spinal measurement system to assist the surgeon with intraoperatively achieving pre-planned alignment-related parameters to the…
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Osteochondrosis
- Trial name
- NCT07023393
- Testing
- Intraoperative spinal measurement system
- Where
- United States
- Sponsor
- Duke University
Disk Herniated Lumbar
Muscle Analyze In Patient With Disc Herniation
This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation.
- Trial name
- NCT05245214
- Testing
- Magnetic Resonance Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Low Back Pain
Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis
To evaluate differences in outcomes in patients receiving steroids compared to those patients randomized to the local anesthetic group who did not receive steroids.
- Trial name
- NCT01052571
- Testing
- lumbar transforaminal epidural injections
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Disc Prolapse, Pain
ADALISKIAS: Adalimumab for Acute Disc Prolapse
Aims: To study the efficacy and safety of adalimumab versus placebo in the treatment of acute disc prolapse will be will be compared up to 12 months after the start of study drug treatment.
- Trial name
- NCT01510548
- Testing
- Adalimumab injections for acute disc prolapse patients
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital
Sciatica, Intervertebral Disc Displacement
Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation
This trial will evaluate the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of…
- Trial name
- NCT02384928
- Testing
- Shinbaro pharmacopuncture, Acupuncture, Conventional medicine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Jaseng Medical Foundation
Disc Herniation
Effect of Discharge Education on Discharge Readiness and Satisfaction
Today, the increase in the cost of health services, the development of technology and the shortening of the hospitalization period day by day due to the reasons for preventing complications such as hospital infections have…
- Trial name
- NCT05695014
- Testing
- Teach Back Metod
- Where
- Cyprus
- Volunteers
- 68 people
- Sponsor
- Eastern Mediterranean University
Lumbar Disc Herniation
Imaging Characteristics of Chronic Lumbar Disc Herniation From the Perspective of Core Muscles and Subcutaneous Fat Tissue Thickness
Fat infiltration and atrophy of lumbar muscles are related to spinal degenerative conditions, which can be seen reliably on MRI scans of lumbar disc herniation (LDH) patients.
- Trial name
- ICCLDHPCMSFT (NCT05649592)
- Testing
- Magnetic Resonance Hydrolipid Separation Imaging
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Zhan Yunfan
Neck Pain, Cervical Radiculopathy
Effectiveness and Safety of Korean Medicine Treatment for Cervical Disc Herniation
A prospective observational study investigating the effectiveness and safety of integrative Korean medicine treatment in cervical disc herniation patients with neck pain or cervical radiculopathy at 4 locations of Jaseng Hospital…
- Conditions
- Neck Pain, Cervical Radiculopathy, Intervertebral Disc Displacement
- Trial name
- NCT03959098
- Testing
- Herbal medicine, Chuna manual medicine, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Jaseng Medical Foundation
Intervertebral Disc Displacement, Sciatica
Outcome of Surgery for Sciatica - a Comparison of Data From Three National Quality Registries
Purpose: The incidence of surgery for lumbar disc hernia varies. According to the national spine registries in Sweden, Norway and Denmark, there is a 30-60% difference in surgical incidence between these countries.
- Trial name
- NCT02889484
- Testing
- Lumbar disc hernia surgery
- Volunteers
- 7,500 people
- Sponsor
- Karolinska Institutet
Lumbago, Lumbar Spinal Stenosis
Post Epidural Steroid Injection Follow-up
To determine the expected pain response timeline for patients receiving epidural steroid injections, our team plans to assess patient pain severity and degree of pain relief every 3 days for 23 days.
- Conditions
- Lumbago, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04207606
- Testing
- Post Epidural Steroid Injection Follow-up
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Lumbar Spine Stenosis, Lumbar Disc Herniation
Dynamic Compliance-Guided Ventilation in Lumbar Surgery
Postoperative pulmonary complications are a frequent cause of morbidity following lumbar stabilization surgery. Conventional ventilation strategies may not adequately reflect intraoperative changes in respiratory mechanics…
- Conditions
- Lumbar Spine Stenosis, Lumbar Disc Herniation, Ventilator-Induced Lung Injury, Postoperative Complications
- Trial name
- NCT07349719
- Testing
- Dynamic Compliance Guided Ventilation, Standard Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara City Hospital Bilkent
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Herniated Lumbar Disc
Postoperative Pain and Analgesic Use Following Lumbar Discectomy: A Comparative Study of Endoscopic Surgery and Open Surgery
The lifetime prevalence of lumbosacral radiculopathy is 3 to 5 percent. The most common cause is a lumbar disc herniation. In 10 to 20 percent of patients, medical treatment is insufficient, and surgery is recommended.
- Trial name
- DISCOPAIN (NCT07766031)
- Testing
- Endoscopic surgery, Open surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Cervical Lordosis Rehabilitation
Does Improvement Towards a Normal Cervical Sagittal Configuration Aid in the Management of Lumbosacral Radiculopathy
A randomized controlled study with six months follow-up will be conducted to investigate the effects of sagittal head posture correction on 3D spinal posture parameters, back and leg pain, disability, and S1 nerve root function…
- Trial name
- NCT05553002
- Testing
- Deneroll cervical extension traction, Traditional treatment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Laminectomy, Postperative Pain Management
Dexamethasone as ESPB Adjuvant in Lumbar Laminectomy
Laminectomy is a routine procedure for patients with lumbar spinal stenosis, offering significant benefits such as reduced low back pain, alleviation of radiculopathy, and improved motor strength 1 23.
- Conditions
- Laminectomy, Postperative Pain Management, Prostaglandin E2, Lumbal Disc Herniation
- Trial name
- NCT07429708
- Testing
- Bilateral ESPB: Ropivacaine 0.375% + Dexamethasone 5mg, Bilateral ESPB: Ropivacaine 0.375%
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Udayana University