Clinical trials: Hernia, Ventral
Umbilical Hernia, Spinal Aneshtesia
Spinal Or General Anesthesia For Umblical Hernia Surgery
In this study, the investigators compared spinal anesthesia under ketofol (ketamine-propofol combination) sedation with general anesthesia in terms of intraoperative and postoperative hemodynamics, respiratory parameters and cost…
- Conditions
- Umbilical Hernia, Spinal Aneshtesia, General Anesthesia
- Trial name
- NCT06426225
- Testing
- General Anesthesia, Spinal Aneshtesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Quality of Life
Robotic Versus Hybrid Assisted Ventral Hernia Repair
Laparoscopic ventral hernia repair (LVHR) may be associated with chronic pain, seroma formation, bulging and failure to restore abdominal wall function.
- Conditions
- Pain, Quality of Life, Recurrence
- Trial name
- ROHYB (NCT05233020)
- Testing
- robotic, hybrid
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Abdominal Wall Hernia
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
The goal of this randomized controlled trial is to compare preoperative intensive weight management to upfront surgery in obese patients undergoing complex abdominal wall reconstruction.
- Trial name
- NCT05925959
- Testing
- Preoperative Weight Management Program
- Where
- 2 sites in United States
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Miller
Ventral Hernia
Post-market Study of the Biodesign Hernia Graft
The purpose of this study is to collect data on the performance of the Biodesign® Hernia Graft when used to reinforce soft tissues during ventral hernia repair.
- Trial name
- NCT04294446
- Testing
- Biodesign Hernia Graft
- Where
- 3 sites in United States, Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cook Biotech Incorporated
Hernia
Collagen Analysis and Genetic Analysis of Families With Tendency to Hernias
Analysis of collagen subtype subcutaneously and genetic analysis of patients from families with a tendency to hernias. Furthermore circulating biomarkers and biomarkers extracted from the subcutaneously tissue such as MMP's…
- Trial name
- NCT00991484
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Open Midline Laparotomy
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for…
- Trial name
- PREVENT (NCT03911700)
- Testing
- Phasix™ Mesh
- Where
- 32 sites in United States, Austria and 3 more
- Volunteers
- 477 people
- Sponsor
- C. R. Bard
Ventral/Incisional Hernia Repairs
Trunk Strength Study
The purpose of this study is to measure abdominal wall strength both preoperatively and postoperatively in patients undergoing ventral/incisional hernia repairs.
- Trial name
- NCT01300936
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kentucky
Hernia, Abdominal
Population Based Strategies for Standardized Surgical Care
Evidence-based guidelines to improve clinical care for abdominal wall hernia repair are common, but adherence is low. This proposal aims to evaluate a stakeholder informed Replicating Effective Programs (REP) using a randomized…
- Trial name
- NCT07106541
- Testing
- Replicating Effective Programs (REP), REP with facilitation (REP-PLUS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Michigan
Ventral Hernia
Mesh Type in Ventral Hernia Repair
Ventral hernias are common following abdominal surgery. Currently, there is no equipoise on when synthetic and biologic meshes should be used.
- Trial name
- NCT03091790
- Testing
- Synthetic Mesh, Biologic Mesh
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- The University of Texas Health Science Center, Houston
Abdominal Wall Defect, Abdominal Wall Hernia
The Efficacy and Security of the Small Stitch Technique in Emergency Surgery
This study evaluates the abdominal closure technique in emergency surgery. Half of participants will be perform the classic Large Stitch technique, while the other half will undergo the Small Stitch technique.
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Eventration, Evisceration; Operation Wound
- Trial name
- STCU (NCT03765060)
- Testing
- Monomax® 2/0 HR26, Monomax® 1 HR48
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Large Midline Ventral Hernia
Anterior Component Separation Versus Posterior Component Separation for Repair of Large Ventral Hernias
This study evaluates effect of anterior component separation and posterior component separation and transversus abdominis muscle release methods for treatment of midline ventral hernias.
- Trial name
- NCT03793738
- Testing
- Anterior component separation, Posterior component separation
- Where
- Georgia
- Volunteers
- 40 people
- Sponsor
- Zaza Demetrashvili
Ventral Hernia
Cost Evaluation of Robotic Ventral Hernia Repair
To evaluate the procedural cost of robotic ventral hernia repair compared with open ventral hernia repair.
- Trial name
- NCT06232148
- Testing
- Type of surgery
- Volunteers
- 3,000 people
- Sponsor
- Bispebjerg Hospital
Ventral Hernia, Incisional Hernia
A Prospective, Multi-Center Study of Phasix™ Mesh for Ventral or Incisional Hernia Repair.
Single-arm study of Phasix Mesh in High Risk patients looking at SSI and recurrence rates.
- Trial name
- NCT01961687
- Testing
- Resorbable Mesh
- Where
- 16 sites in United States
- Volunteers
- 121 people
- Sponsor
- C. R. Bard
Ventral Hernia
A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery
The objective of this study is to collect efficacy, safety and utility data with Phasix™ Mesh in ventral and incisional repair procedures by evaluating the following: 1.
- Trial name
- NCT01863030
- Testing
- Phasix mesh implant
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- John Roth
Ventral Hernia
Absorbable Versus Permanent Mesh Fixation Trial in Laparoscopic Midline Ventral Hernia Repair
To compare the use of absorbable tackers versus permanent tack fixation using a polyester large pore mesh in laparoscopic midline ventral hernia repair in a multicenter (Belgian) prospective randomized single-blinded trial.
- Trial name
- SORBET (NCT01109771)
- Testing
- permanent mesh fixation, absorbable mesh fixation
- Where
- 11 sites in Belgium
- Volunteers
- 105 people
- Sponsor
- University Hospital, Ghent
Umbilical Hernia
Mesh Versus Suture Repair in Umbilical Hernias - A Multicenter Trial
Umbilical hernia repair is one of the most common surgical performance in general surgery. Up to now, the use of suture repair has been the preferred technique for small umbilical hernia defects without any gold standard…
- Trial name
- SUMMER (NCT04231071)
- Testing
- Onlay Mesh group
- Where
- 7 sites in Sweden
- Volunteers
- 288 people
- Sponsor
- Karolinska Institutet
Umbilical Hernia
Cosmetic Outcomes of Umbilical Hernia Incisions
This will be a single institution, prospective, randomized controlled trial. Patients presenting as an outpatient for repair of umbilical hernias who meet our inclusion criteria, whose parents provide permission to participate in…
- Trial name
- UHR (NCT06738121)
- Testing
- Infra-umbilical incision, Transumbilical incision
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Children's Mercy Hospital Kansas City
Hernia, Ventral
The Use of Local Hemostatic in Patients With Large Incisional Hernias
Design of a simple blind randomized controlled trial study. Large incisional hernia repair with use of local hemostatic Hemoblock
- Trial name
- NCT04222517
- Testing
- Incisional hernia repair by the mesh implant in sublay retromusuclar position, Incisional hernia repair by the mesh implant in sublay retromusuclar position with using a local hemostatic Hemoblock
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- Nijznevartovsk County Clinical Hospital
Hernia, Ventral, Laparoscopy
Peritoneal Bridging in Laparoscopic Ventral Hernia Repair
Laparoscopic ventral hernia repair (VHR) is usually performed by reducing the contents in the hernia sac from the abdominal cavity and then covering the defect from the inside with a mesh, i.e. Intraperitoneal Onlay Mesh (IPOM).
- Conditions
- Hernia, Ventral, Laparoscopy, Seroma
- Trial name
- BriClo (NCT03344575)
- Testing
- Conventional defect closure, Peritoneal bridging
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet