Clinical trials: Hernia, Umbilical
Postoperative Pain
Does Preoperative Caldolor Decrease the Requirement for Postoperative Narcotics
Caldolor® is an intravenous (IV) formulation of ibuprofen encompassing analgesic, anti-inflammatory and antipyretic (anti-fever) properties.
- Trial name
- NCT01297829
- Testing
- Intravenous Ibuprofen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- St. Barnabas Medical Center
Anesthesia, Spinal, Ambulatory Surgical Procedures
Spinal Anesthesia for Outpatient Abdominal Wall Surgery: Comparison of Bupivacaine, 2-chloroprocaine and Prilocaine
Considering fast-track principles, an ideal spinal anesthetic should have minimal complications and above all fast recovery so reducing in-hospital stay.
- Conditions
- Anesthesia, Spinal, Ambulatory Surgical Procedures, Hernia, Inguinal, Hernia, Umbilical
- Trial name
- spinal (NCT02813382)
- Testing
- Bupivacaine, Prilocaine, Chloroprocaine
- Volunteers
- 101 people
- Sponsor
- AZ St.-Dimpna Geel
Congenital Diaphragmatic Hernia
Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord
Congenital diaphragmatic hernia (CDH) is a severe birth defect, with a prevalence of 1:2000 to 1:3000 live births where a defect in the diaphragm results in, herniation of the abdominal contents into the chest with subsequent…
- Trial name
- NCT03242044
- Testing
- Congenital diaphragmatic hernia resuscitation with an intact umbilical cord
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Umbilical Hernia, Spinal Aneshtesia
Spinal Or General Anesthesia For Umblical Hernia Surgery
In this study, the investigators compared spinal anesthesia under ketofol (ketamine-propofol combination) sedation with general anesthesia in terms of intraoperative and postoperative hemodynamics, respiratory parameters and cost…
- Conditions
- Umbilical Hernia, Spinal Aneshtesia, General Anesthesia
- Trial name
- NCT06426225
- Testing
- General Anesthesia, Spinal Aneshtesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ankara City Hospital Bilkent
Ventral Hernia
Laparoscopic Ventral Hernia Repair with Routine Defect Closure Using Su2ura® Approximation Device
Study includes 5 visits: Screening, Baseline/Surgery, and 14 days, 3 months, 12months Follow-Ups post-surgery. The actual point of enrollment for each subject is considered the day of surgery.
- Trial name
- NCT04986917
- Testing
- Hernia repair surgery using the Su2ura® approximation device, Physical Examination, Vital Signs
- Where
- 2 sites in Israel
- Volunteers
- 18 people
- Sponsor
- Anchora Medical
Umbilical Hernia, Liver Cirrhosis
Conservative Treatment Versus Elective Repair of Umbilical Hernia in Patients With Ascites and Liver Cirrhosis
The purpose of the present study is to investigate whether or not to perform elective surgical repair of umbilical hernias in patients with liver cirrhosis and ascites.
- Conditions
- Umbilical Hernia, Liver Cirrhosis, Ascites
- Trial name
- CRUCIAL (NCT01421550)
- Testing
- Conservative treatment, Surgical repair
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Erasmus Medical Center
Omphalocele
Omphaloceles and Associated Malformations
Major birth defects like omphalocele are diagnosed in 3-8% of all newborns in Germany each year. Prevention and treatment quality of congenital malformations are key concerns for child health.
- Trial name
- NCT04126863
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- University Hospital Tuebingen
Congenital Diaphragmatic Hernia, Omphalocele
Functional Evaluation of the Fetal Lung by Functional Magnetic Resonance Imaging - Blood Oxygenation Level Dependent (MRI-BOLD), in Congenital Diaphragmatic and Parietal Malformations
The objective is to evaluate the quality of the response to the Blood Oxygen Level Dependent effect in fetuses with diaphragmatic hernias and abdominal wall malformations and to correlate with postnatal respiratory outcome.
- Conditions
- Congenital Diaphragmatic Hernia, Omphalocele, Gastroschisis
- Trial name
- BOLD FETUS (NCT04186039)
- Testing
- Functional magnetic resonance imaging - Blood Oxygenation Level Dependent
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ultrasound, External Oblique
Ultrasound Guided External Oblique and Rectus Abdominis Plane Block (EXORA) on Neuroendocrine Stress Response in Adults Undergoing Umbilical Hernia Surgery
This study aims to evaluate the efficacy of ultrasound-guided external oblique and rectus abdominis plane block on the neuroendocrine stress response and postoperative analgesia in adults undergoing umbilical hernia repair.
- Conditions
- Ultrasound, External Oblique, Rectus Abdominis Plane Block, Neuroendocrine Stress Response
- Trial name
- NCT07324863
- Testing
- General anesthesia, External oblique and rectus abdominis plane (EXORA) block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Cholecystolithiasis, Incisional Hernia
Risk of Umbilical Trocar-site Hernia After SILC Cholecystectomy Versus Conventional Cholecystectomy
Background Laparoscopic cholecystectomy is a very common procedure. Postoperative pain, especially around the umbilical port is dominating the first postoperative week.
- Trial name
- UMBI-SILS (NCT01740973)
- Where
- Denmark
- Volunteers
- 699 people
- Sponsor
- Hvidovre University Hospital
Abdominal Hernia
Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome
In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach.
- Trial name
- NCT05906017
- Testing
- Open Hernia surgery, Robotic Hernia surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Southern Denmark
Umbilical Hernia
Randomized Controlled Trial (RCT) Umbilical Hernia Repair (UHR) Absorbable vs Non-absorbable Synthetic Mesh
The goal of this study is to see which of two types of mesh is better for fixing an umbilical hernia. One type of mesh is an absorbable synthetic mesh, which goes away on its own in the body, and the other type of mesh is a…
- Trial name
- NCT05994248
- Testing
- Enform Mesh, Marlex
- Sponsor
- Wake Forest University Health Sciences
Cirrhosis, Umbilical Hernia
Elective Umbilical Hernia Repair in Patients With Cirrhosis
Liver cirrhosis is a frequent and severe chronic disease. About 20 % of patients with liver cirrhosis develop umbilical hernias. In comparison, the prevalence in the general population is around 2 %.
- Trial name
- NCT04687579
- Testing
- Screening, Preoperative optimization, Umbilical hernia repair
- Volunteers
- 51 people
- Sponsor
- Hvidovre University Hospital
Umbilical Hernias, Ventral Hernias
Prospective Evaluation of the Proceed Ventral Patch With and Without Laparoscopic Evaluation
For small (2-3cm) ventral and umbilical hernias the discussion for primary suture repair or the use of mesh continues. About 5 years ago the Ventralex patch was introduced, which combines a layer of PTFE mesh with a small…
- Trial name
- NCT01183325
- Testing
- Proceed Ventral Patch placement
- Where
- 2 sites in Belgium
- Volunteers
- 160 people
- Sponsor
- University Hospital, Ghent
Hernia, Hernia, Ventral
Preoptimisation in Ventral Hernia Surgery
The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation…
- Conditions
- Hernia, Hernia, Ventral, Hernia Incisional, Hernia, Umbilical
- Trial name
- PreOpt (NCT07316426)
- Testing
- preoptimisation programme
- Where
- 5 sites in Sweden
- Volunteers
- 130 people
- Sponsor
- Umeå University
Umbilical Cord Clamping, Congenital Diaphragmatic Hernia
Physiological Umbilical Cord Clamping in Patients With Congenital Diaphragmatic Hernia. Clinical Trial
Congenital diaphragmatic hernia (CDH) is a malformation that affects 1 in every 3000 newborns. The diaphragm does not complete its closure during embryogenesis, which allows the abdominal organs to herniate into the thoracic…
- Conditions
- Umbilical Cord Clamping, Congenital Diaphragmatic Hernia, Delayed Umbilical Cord Separation
- Trial name
- NCT06408376
- Testing
- Physiological cord clamping
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Hospital JP Garrahan
Abdominal Wall Hernia, Umbilical Hernia Repair
Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment
The goal of this clinical trial is to investigate whether mesh-suture affects wound complication rates, patient-reported quality of life, and operation time in adult patients undergoing surgery for small ventral hernias.
- Conditions
- Abdominal Wall Hernia, Umbilical Hernia Repair, Epigastric Hernia Repair
- Trial name
- MeMa (NCT07476560)
- Testing
- mesh suture, planar mesh
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Regionshospital Nordjylland
Cirrhosis, Sarcopenia
Prevalence of Sarcopenia and Undernutrition in Patients With Cirrhosis and Abdominal Hernia
The study evaluates whether sarcopenia influences the prevalence of abdominal hernias in patients with cirrhosis.
- Conditions
- Cirrhosis, Sarcopenia, Malnutrition, Hernia, Abdominal
- Trial name
- NCT03458845
- Testing
- Computed Tomography Scan
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Incisional Hernia, Cholecystectomy, Laparoscopic
Trocar Site Hernia After Laparoscopic Cholecystectomy, Supra Versus Infraumbilical Incision for Umbilical Trocar Entry
Trocar site hernia is a specific complication of laparoscopic surgery. The increasingly frequent use of the laparoscopic approach has resulted in an increase in the number of hernias, mainly at the umbilical area.
- Trial name
- HOT (NCT04254237)
- Testing
- Infraumbilical Hasson trocar incision, Supraumbilical Hasson trocar incision
- Where
- 3 sites in Spain
- Volunteers
- 130 people
- Sponsor
- Complejo Hospitalario La Mancha Centro
External Oblique and Rectus Abdominis Plane, Postoperative Analgesia
External Oblique and Rectus Abdominis Plane (EXORA) Block for Postoperative Analgesia in Patients Undergoing Umbilical Hernia Repair
This study aims to evaluate the effect of the external oblique and rectus abdominis plane (EXORA) block for postoperative analgesia in patients undergoing umbilical hernia repair.
- Conditions
- External Oblique and Rectus Abdominis Plane, Postoperative Analgesia, Umbilical Hernia Repair
- Trial name
- NCT07012603
- Testing
- External oblique and rectus abdominis plane (EXORA) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University