Clinical trials: Hereditary Sideroblastic Anemia
Anemia, Iron Deficiency, Pregnancy Anemia
Iron Deficiency Anemia in the Second and Third Trimester of Pregnancy
Iron deficiency is the most frequent cause of anemia during pregnancy and of maternal blood transfusion during the post-partum period.
- Trial name
- PESO (NCT07163390)
- Testing
- Sideral Folico
- Volunteers
- 82 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anemia, Iron Deficiency, Anemia of Chronic Disease
Anemia of Inflammation and Deficiency Anemia
Critical patients which requiring admission to intensive care (IT) are a special group of patients. In these patients the prevalence of anemia reported in studies is 75%.
- Trial name
- AIDA (NCT04071067)
- Where
- 2 sites in Romania
- Volunteers
- 1,000 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Iron Deficiency Anaemia, Iron Deficiency Anemia
Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose vs Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
The trial was designed to evaluate the incidence of unintended hypophosphatemia (low level of phosphate in the blood) in subjects with iron deficiency anaemia (IDA).
- Trial name
- NCT03238911
- Testing
- Iron isomaltoside/ferric derisomaltose, Ferric carboxymaltose
- Where
- 16 sites in United States
- Volunteers
- 123 people
- Sponsor
- Pharmacosmos A/S
Methemoglobinemia, Anemia, Iron-Deficiency
Ferric Carboxymaltose Methemoglobinemia Study
Anemia that develops due to iron deficiency is called iron deficiency anemia. This common condition is treated with iron supplements taken either orally or given through an intravenous (IV) infusion.
- Conditions
- Methemoglobinemia, Anemia, Iron-Deficiency, Parenteral Iron Therapy, Ferric Carboxymaltose
- Trial name
- FerMet (NCT06958822)
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 977 people, healthy volunteers welcome
- Sponsor
- Ordu University
Iron Deficiency Anemia
Assessment of the Bioavailability of Iron in Iron Fortified Bouillon Cubes in Healthy Nigerian Women
The prevalence of iron deficiency anemia is a wide spread problem in Africa and iron fortification can be an effective strategy to decrease this.
- Trial name
- NCT02815449
- Testing
- Meals prepared with iron fortified cube with Low stabilizer level, Meals prepared with iron fortified cube with Medium stabilizer level, Meals prepared with iron fortified cube with High stabilizer level
- Where
- Nigeria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Inflammatory Bowel Disease, Iron Deficiency Anemia
EffiCacy and sAfEty of Low doSe orAl iRon for Anaemia in IBD
Iron deficiency anaemia (IDA) is common in inflammatory bowel disease (IBD). However, although iron is commonly prescribed, the amount of elemental iron needed to achieve clinical efficacy, and the optimal method of…
- Trial name
- CAESAR (NCT06321887)
- Testing
- Ferrous fumarate syrup 2.5ml/70mg (22.5mg elemental iron), Ferrous fumarate syrup 2.5ml/70mg(45mg elemental iron), Ferrous fumarate syrup 2.5ml/70mg (90mg elemental iron)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Iron Deficiency Anemia, Obscure Gastrointestinal Bleeding
Role of AI in CE for the Identification of SB Lesions in Patients With Small Intestinal Bleeding.
Capsule Endoscopy (CE) is a safe, patient friendly and easy procedure performed for the evaluation of gastrointestinal tract unable to be explored via conventional endoscopy.
- Trial name
- ArtIC (NCT04821349)
- Testing
- Capsule endoscopy
- Where
- Italy
- Volunteers
- 137 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Iron-deficiency, Colorectal Cancer
Effects of Intravenous Administered Iron in Non-anemic Iron Deficient Patients With Colorectal Cancer
This double-blinded clinical randomized trial with a 1:1 recruitment ratio between placebo and the active group will aim to investigate the effects of intravenously administered iron in non-anemic iron deficient patients on…
- Trial name
- NAIDIC (NCT05220800)
- Testing
- Iron(III)isomaltoside
- Where
- 3 sites in Denmark
- Volunteers
- 134 people
- Sponsor
- Zealand University Hospital
Anemia, Iron-Deficiency
Non-invasive Optical Detection of Iron Deficiency
This study aims to evaluate a prototype device detecting zinc protoporphyrin-IX fluorescence non-invasively from the intact oral mucosa. Zinc protoporphyrin-IX is an established indicator of iron deficiency.
- Trial name
- NCT02310607
- Testing
- Not an interventional study
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern
Iron-deficiency, Iron Deficiency Anemia
Child of Urban Poverty Iron Project (CUPIP) - A Pilot Study
The first 1,000 days of life are critical periods for brain development. Proper nutrition lays the foundation for optimal growth, health, and neurodevelopment across the lifespan.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Micronutrient Deficiency, Nutrient Deficiency
- Trial name
- CUPIP (NCT03819530)
- Testing
- Vitamin and Mineral Powder
- Where
- Malaysia
- Volunteers
- 45 people
- Sponsor
- University of Malaya
Anemia, Iron Deficiency, Hyperphosphatemia
Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease
A 9-month randomized, double-blind, placebo-controlled study to compare the effect of fixed dose ferric citrate versus placebo in patients with advanced chronic kidney disease (eGFR ≤20 ml/min/1.73m2) on the composite endpoint of…
- Conditions
- Anemia, Iron Deficiency, Hyperphosphatemia, Renal Insufficiency, Chronic, Renal Anemia
- Trial name
- FRONTIER (NCT05085275)
- Testing
- Ferric Citrate 1 GM Oral Tablet [AURYXIA]
- Where
- 23 sites in United States
- Volunteers
- 289 people
- Sponsor
- USRC Kidney Research
Iron Deficiency Anemia
Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients
Postoperative anemia is common in cardiac surgery with cardiopulmonary bypass. Iron deficiency delays the recovery from postoperative anemia and may negatively affect the postoperative trajectory of cardiac surgery patients.
- Trial name
- AGE-ANEMIA (NCT04913649)
- Testing
- Ferric Derisomaltose 100 MG/ML, Sodium chloride
- Where
- 2 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- dr. P. Noordzij
Patient Blood Management, Cardiac Surgery
Effect of the Combined Programme on Perioperative Anaemia（CPPA）
We used the preoperative intervention of iron sucrose in combination with human erythropoietin and vitamin C as an innovative combination therapy.
- Conditions
- Patient Blood Management, Cardiac Surgery, Iron Deficiency Anemia
- Trial name
- NCT05353348
- Testing
- Iron Sucrose, recombinant human erythropoietin, ascorbic acid, conventional treatment
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anemia, Iron Deficiency
Four-Way Crossover Study to Compare Ferric Maltol Capsules and Oral Suspension in Healthy Volunteers
The purpose of the study is to compare the Pharmacokinetics (PK) of the new ferric maltol suspension, in adults, with the existing ferric maltol capsule.
- Trial name
- NCT04626414
- Testing
- Ferric maltol capsule, Ferric maltol suspension
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shield Therapeutics
Anemia, Cardiovascular Disease
Active Preoperative Anemia Management in Patients Undergoing Cardiac Surgery
Anemia which is a decreased blood count or lower than normal hemoglobin (hgb), is a major health problem for patients having heart surgery.
- Trial name
- APART (NCT02189889)
- Testing
- EPO, Feraheme
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Texas Southwestern Medical Center
Refractory Iron Deficiency Anemia
Endoscopy in Anemic Children
Assess the role of Upper and lower gastrointestinal endoscopy in evaluation of refractory iron deficiency anemia in children
- Trial name
- NCT06729489
- Testing
- Upper Endoscopy
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Iron-deficiency
Determination of a Dose-dependent Effect of GOS on Iron Absorption, and Addition of Vitamin C
Iron deficiency is still the most common and widespread nutritional disorder in the world according to WHO. In a recent iron absorption study in adult women with low iron stores in our lab (publication under review), we found…
- Trial name
- Fe_GOS_2 (NCT03762148)
- Testing
- ferrous fumarate, ferrous sulphate, ferric pyrophosphate
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Isabelle Herter-Aeberli
Iron Deficiency Anemia Treatment, Iron-deficiency
IV Iron Versus Standard Treatment for Iron Deficiency Anemia in the Emergency Department
The investigators will retrospectively collect data of patients infused at UMC's emergency department (ED) with long acting irons (ferric carboxymaltose, iron dextran, iron sucrose, etc.), in addition, patients infused with blood…
- Conditions
- Iron Deficiency Anemia Treatment, Iron-deficiency, Iron Deficiency Anemia Due to Blood Loss, Iron Deficiency Anemia
- Trial name
- NCT05153278
- Testing
- Packed red blood cells, Intravenous drug
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Iron Deficiency Anemia
Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient
Given the limited long-term effectiveness of traditional weight loss methods, bariatric surgery is increasingly becoming the preferred option for sustained weight loss.
- Trial name
- NCT04268849
- Testing
- Ferumoxytol, Saline, Ferrous sulfate tablets
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Auerbach Hematology Oncology Associates P C
Cystic Fibrosis, Anemia, Iron-Deficiency
Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis
This study questions whether low-dose ferrous sulfate taken by mouth daily for 6 weeks increases hemoglobin concentration in adult subjects with cystic fibrosis and hypoferremic anemia.
- Trial name
- NCT01755455
- Testing
- Ferrous sulfate 325mg
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Dartmouth-Hitchcock Medical Center