Clinical trials: Hemoglobins
Blood Loss
Comparative Accuracy of Three Versions of Non-Invasive Hemoglobin Monitoring
There is no study hypothesis. The purpose of this study is to compare the accuracy of the: 1) SpHb (Radical 7 Pulse Co-Oximetry with SpHb™) RevF sensor (currently marketed), 2) the SpHb RevG sensor (a new, limited release…
- Trial name
- NCT01604668
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Dehydration
Kinetic Method to Detect Dehydration
1. The distribution and elimination of infusion fluids can be studied by volume kinetics, a mathematical method based on serial analysis of the blood hemoglobin concentration. 2.
- Trial name
- NCT01062776
- Testing
- Dehydration
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
HbS Disease, Hemoglobin S Disease
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD
HSCT is currently the only curative option for SCD but less than 20% of SCD patients have a MD donor available. So far, all curative approaches beyond a MSD HSCT at young age are non-satisfactory.
- Conditions
- HbS Disease, Hemoglobin S Disease, Sickle Cell Anemia, Sickle Cell Disorders
- Trial name
- NCT04201210
- Testing
- TCRα/β+ and CD19+ depleted haploidentical stem cell transplantation, Matched sibling donor transplantation
- Where
- 9 sites in Austria, Germany
- Volunteers
- 212 people
- Sponsor
- University of Regensburg
Anemia
A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant
This 2 arm study will assess the efficacy, safety and tolerability of subcutaneous Mircera, versus no ESA therapy, in chronic kidney disease patients with anemia after kidney transplant, not currently treated with ESA.
- Trial name
- NCT00576602
- Testing
- methoxy polyethylene glycol-epoetin beta [Mircera], Supportive treatment
- Where
- 20 sites in Belgium, France and 4 more
- Volunteers
- 1 people
- Sponsor
- Hoffmann-La Roche
Anemia
The Effect of Ferric Carboxymaltose on Hemoglobin and Blood Transfusion in Cardiac Surgery
Anemia after cardiac surgery is a vast phenomena. More than 70% of the patients who under went surgery represented with hemoglobin less than 8 mg/dl (the cutoff for blood transfusion) and more than 80% of the patients receives at…
- Trial name
- NCT02939794
- Testing
- Ferinject
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus
Prematurity Complications, Anemia
Personalizing Preterm Neonatal Transfusions With Fetal Hemoglobin-Enriched Cord Blood
Long-term morbidities among very low birth weight infants remain a significant challenge. Oxidative stress is a key factor in the pathogenesis of 'free radical (FR) diseases of prematurity,' including retinopathy of prematurity…
- Trial name
- ANH-Prestige (NCT07636473)
- Testing
- Cord Blood Red Blood Cell Transfusion (CB-RBC), Adult Donor Red Blood Cell Transfusion (A-RBC)
- Volunteers
- 200 people
- Sponsor
- University of Parma
Diabetes Mellitus, Type 1
Long-term, Implantable Sensor Improves Health Outcomes in Patients With T1D
The implantable Eversense ® CGM System obtained CE marking in 2016 for the 90-day device and in 2017 for the 180-day device.There is interest in real-world clinical evidence on the use of Eversense regarding changes in HbA1c and…
- Trial name
- NCT04160156
- Testing
- Long term sensor
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Magna Graecia
Anaemia
Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia
This study is intended to evaluate the dose-response relationship of GSK1278863 over the first 4 weeks of treatment and evaluate the safety and efficacy of GSK1278863 over 24 weeks to maintain hemoglobin (Hgb) level in…
- Trial name
- NCT01977482
- Testing
- GSK1278863, rhEPO
- Where
- 107 sites in United States, Australia and 14 more
- Volunteers
- 216 people
- Sponsor
- GlaxoSmithKline
Anemia
A Randomized Clinical Trial on Hemoglobin Dose and Patient Matching
The aim of this study is to evaluate whether the targeted hemoglobin increment (2 grams per decilitre) in the patient can be predicted from the hemoglobin dose/weight of the blood bag transfused.
- Trial name
- NCT01328262
- Testing
- Calculated red blood cell transfusion, Standard red blood cell transfusion
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Haukeland University Hospital
Anemia
An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Renal Anemia
This observational study will investigate hemoglobin levels and Mircera (methoxy polyethyleneglycol-epoetin beta) dose over time in patients with chronic kidney disease, and compare standards of care between centers.
- Trial name
- NCT01051323
- Testing
- methoxy polyethylene glycol-ep [Mircera]
- Where
- Germany
- Volunteers
- 1,580 people
- Sponsor
- Hoffmann-La Roche
Anemia, Iron Deficiency, Cardiometabolic Disease
The Impact of Faba Bean Rich Bread on Iron Status, Postprandial Lipaemia and Satiety
High levels of animal proteins (meat) in the diet are linked with a greater risk of developing heart disease and other long-term health conditions.
- Conditions
- Anemia, Iron Deficiency, Cardiometabolic Disease, Low Iron Stores
- Trial name
- RtP (NCT06466746)
- Testing
- Raising the Pulse faba bean-enriched bread, Conventional White Bread
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Reading