Clinical trials: Hemodynamics
Accuracy and Precision of Noninvasive Measurement
CNAP Accuracy Dependent on Hemodynamic Variables
Agreement of CNAP pressure with invasive pressure is evaluated dependent on hemodynamic variables achieved by a PICCO monitor. Hypothesis: Low cardiac output and volume status but not high vascular resistance affect the accuracy…
- Trial name
- NCT01743846
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic
Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning
Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes .
- Conditions
- This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic, Maternal Positioning During CS
- Trial name
- NCT06857162
- Testing
- Positioninng during Cs
- Where
- Egypt
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Aswan University
Thyroid Nodules
Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules
The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.
- Trial name
- NCT00507897
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Yaroslavl State Medical Academy
Cardiogenic Shock, Acute Myocardial Infarction
National Cardiogenic Shock Initiative
This study evaluates the use of early mechanical circulatory support in patients presenting with acute myocardial infarction and cardiogenic shock.
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCSI (NCT03677180)
- Where
- 75 sites in United States
- Volunteers
- 406 people
- Sponsor
- Henry Ford Health System
Oliceridine
Oliceridine Dose for Tracheal Intubation Hemodynamic Elevation: Up-and-Down Trial
This is a clinical trial using an up-and-down sequential design, aiming to investigate the median effective dose (ED50) and 95% effective dose (ED95) of oliceridine for inhibiting hyperdynamic responses induced by tracheal…
- Trial name
- NCT07154979
- Testing
- Oliceridine Injection
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Shiyou Wei
Heart Failure With Preserved Ejection Fraction, Arterial Hypertension
Ambulatory Blood Pressure in HFPEF Outcomes Global Registry
Heart failure and preserved ejection fraction (HFPEF) is a disease with increasing prevalence world wide. Due to its etiological and prognostic relationship with hypertension, it is highly interesting to know the characteristics…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Arterial Hypertension, Frailty Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- HFPEFGlobal (NCT04065620)
- Testing
- ambulatory blood pressure measurement
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Clinic of Barcelona
Hemodynamic Instability
The Bolus Dose of Dexmedetomidine (ED50) That Avoids Hemodynamic Compromise in Children
Dexmedetomidine is a sedative drug that has many benefits when given to children under anesthesia, such as improved pain relief and reduced agitation following their surgery.
- Trial name
- DexMED (NCT01498380)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heart Failure, Cardiomyopathy, Dilated
Impact of Intraventricular Electrical Activation in Resynchronization Therapy
Impact of intraventricular electrical activation in resynchronization therapy. We seek to evaluate the impact of Cardiac Resynchronization Therapy (CRT) on electrical activation of the Left Ventricle (LV).
- Conditions
- Heart Failure, Cardiomyopathy, Dilated, Coronary Disease
- Trial name
- CARTO-CRT (NCT01270646)
- Testing
- Invasive mapping with CARTO3 system and Non-Invasive mapping with CardioInsight Atlas EC Mapping system
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Bordeaux
Dialysis Related Complication, Dialysis Hypotension
Expanded Hemodialysis Versus Online Hemodiafiltration
Conventional hemodialysis (HD) is essential for the treatment of end-stage renal disease (ESRD) patients, by reducing serum concentration of uremic toxins and correcting fluid overload.
- Conditions
- Dialysis Related Complication, Dialysis Hypotension, Hemodialysis-Induced Symptom
- Trial name
- NCT03274518
- Testing
- Expanded Hemodialysis, Online Hemodiafiltration
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- University of Sao Paulo
Fluid Challenge, Hemodynamic Monitoring
Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness.
In order to predict fluid responsiveness in the operating room and therefore benefit of performing fluid administration to improve patient's hemodynamic status, it will test two ventilation strategies : the Tidal Volume Challenge…
- Trial name
- TIDALEC (NCT04535115)
- Testing
- Starting LRM (Lung Recruitment Maneuver), Starting VtC (Tidal Volume Challenge)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Lille
Surgery, Colorectal
Perioperative Colloid vs Crystalloid in Patients Undergoing Colorectal Surgery
The primary purpose of this study is to determine the effect of a balanced 6%hydroxyethyl starch 130/0.4 vs. a balanced crystalloid in colorectal surgery.
- Trial name
- KoKris (NCT01303250)
- Testing
- balanced 6% hydroxyethylstarch 130/0.4, balanced crystalloid
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- University Hospital Muenster
Multimorbidity, Multiple Chronic Conditions
Effect of Aerobic Training on the Health Parameters of Postmenopausal Women With Multimorbidity
People affected by multiple chronic diseases have a greater chance of hospitalization, longer hospital stays, worse general health, worse physical and mental function and lower functional capacity, with an average risk of 50% of…
- Conditions
- Multimorbidity, Multiple Chronic Conditions, Hypertension, Dyslipidemias
- Trial name
- NCT05075902
- Testing
- Aerobic training
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Coronary Artery Disease, Unstable Angina
Restore EF Observational Study
A multi-center, prospective, observational, non-interventional single arm, study of the intermediate-term clinical outcomes collected from electronic health records of high-risk patients which have previously undergone standard…
- Conditions
- Coronary Artery Disease, Unstable Angina, Angina, Stable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCT04648306
- Testing
- Prophylactic Impella support for a non-emergent PCI
- Where
- 21 sites in United States
- Volunteers
- 406 people
- Sponsor
- Abiomed Inc.
Dialysis; Complications
Effect of Sodium and UF Profiling on Dialysis
The aim of this study is to evaluate the effects of sodium and UF profiling on hemodynamic stability, interdialytic weight gain, and intradialytic complications
- Trial name
- NCT06213129
- Testing
- Na and ultrafiltration profiling
- Volunteers
- 30 people
- Sponsor
- Assiut University
Aneurysmal Subarachnoid Hemorrhage
Cerebral Hemodynamic Optimization by Milrinone to Prevent Delayed Cerebral Ischemia
The present study is a randomized, multi-center, double-blind, prospective study that tests the efficacy of intravenous milrinone to optimize cerebral hemodynamic and prevent delayed cerebral ischemia (DCI) during the high-risk…
- Trial name
- OPTIMIL (NCT04282629)
- Testing
- Milrinone Injection
- Where
- 5 sites in France
- Volunteers
- 234 people
- Sponsor
- University Hospital, Toulouse
Anesthesia, Dexmedetomidine
Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery
Ambulatory surgery is increasingly used in anesthesia. In case of general anesthesia, it is recommended to use anesthesia molecules with a short half-life and low doses of opiates to ensure a rapid awakening and to prevent nausea…
- Conditions
- Anesthesia, Dexmedetomidine, Hemodynamics, Ambulatory Care
- Trial name
- DEXCOEUR (NCT06082856)
- Testing
- Dexmedetomidine, Sufentanil
- Where
- France
- Volunteers
- 594 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Coronary Artery Disease, Hemodynamic Monitoring
Single Transpulmonary Thermodilution and Continuous Monitoring of Central Venous Oxygen Saturation During Off-pump Coronary Surgery
The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen…
- Conditions
- Coronary Artery Disease, Hemodynamic Monitoring, Goal Directed Therapy
- Trial name
- OPCAB (NCT00624494)
- Testing
- Conventional monitoring, Advanced monitoring
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Cardiovascular Diseases, Lidocaine Causing Adverse Effects in Therapeutic Use
Evaluation of the Effect of 10% Lidocaine Spray Undergoing Coronary Artery Bypass Graft Operation
In patients undergoing coronary bypass surgery; 10% topical lidocaine administered endotracheally before intubation is to investigate the effect of hemodynamic response and EKG paramater after intubation.
- Conditions
- Cardiovascular Diseases, Lidocaine Causing Adverse Effects in Therapeutic Use, Tracheal Intubation Morbidity
- Trial name
- ELCABG (NCT03304431)
- Testing
- Orotracheal Lidocaine Oral Spray application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Deep Vein Thrombosis, Total Hip Arthroplasty
Neuromuscular Electrical Stimulation Following Total Hip Arthroplasty
Patients post total hip arthroplasty (THA) remain at high risk of developing Deep Vein Thrombosis (DVT) during the recovery period following surgery despite the availability of effective pharmacological and mechanical…
- Trial name
- NCT01785251
- Testing
- Neuromuscular Electrical Stimulation
- Where
- Ireland
- Volunteers
- 11 people
- Sponsor
- National University of Ireland, Galway, Ireland
COVID
Compensatory Reserve Index (CRI) for Management of COVID-19
The FDA has approved the CipherOx CRI T1 Tablet for use in subjects aged 19-36, and that this study aims to evaluate the device in subjects aged outside of this range and is being used off label.
- Trial name
- NCT04457817
- Testing
- CRI
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Colorado, Denver