Clinical trials: Hemodynamics
Heart Failure, Congestive
Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
Heart failure with preserved ejection fraction or HFpEF, represents nearly 50% of all heart failure cases and is particularly common in the elderly. The disease has no current treatment options.
- Trial name
- NCT02772068
- Testing
- Istaroxime, Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Benjamin Levine
Cesarean Section, Hemodynamic Instability
Low-Doses Of Isobaric Bupivacaine On Intraoperative Hemodynamics In Spinal Anesthesia During Cesarean Section
The primary aim of this study was to compare the effects of two different low-dose bupivacaine used in spinal anesthesia on intraoperative hemodynamics in cesarean section operations.Investigators think that low-dose bupivacaine…
- Trial name
- NCT05136040
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Healthy, Congenital Heart Disease
A Study of Invasive Hemodynamic for MACHD Registry
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
- Trial name
- NCT05849025
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Effect of Azimilide Dihydrochloride on Renal Function
This study will assess the effect of multiple dosing of 125 mg azimilide on glomerular filtration rate (GFR) and total creatinine clearance (GFR + active secretion) in healthy subjects.
- Trial name
- NCT00318838
- Testing
- Azimilide dihydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Neuroimaging
Evaluation of the Implementation of the Hemispheric Dominance During Development
Many cognitive functions in human are based on asymmetric brain networks. For most adults, language is processed largely by the left hemisphere while other auditory treatments, such as voice recognition are rather based on the…
- Trial name
- HEMISPHERENOR (NCT02826733)
- Testing
- Electroencephalogram (EEG), Near Infra Red Spectroscopy (NIRS), magnetic resonance imaging (MRI)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Trigemino-Cardiac Reflex, Impacted Third Molar Tooth
The Frequency of Trigeminocardiac Reflex During the Extraction of Impacted Mandibular Wisdom Teeth
The goal of this clinical trial is to investigate trigeminocardiac reflex (TCR) formation during surgical extraction of mandibular impacted wisdom teeth in healthy adults.
- Trial name
- NCT06499532
- Testing
- Monitoring and Surgical removal of mandibular impacted wisdom teeth, using Gow-Gates anesthesia technique, Monitoring and Surgical removal of mandibular impacted wisdom teeth, using inferior alveolar nerve block anesthesia technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Oxygen Metabolism, Muscle Spasticity
Hemodynamic Changes During Dry Cupping Therapy on Low Back Pain
This study aims to investigate the hemodynamic changes during dry cupping therapy (DCT) on low back pain. 50 patients with low back pain as experimental group and 50 healthy people as control group are treated by DCT.
- Trial name
- NCT03816787
- Testing
- Negative pressure therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Cesarean Section, Anxiety
Reflexology Hand Massage After Cesarean Section
Background: Globally, cesarean section (CS) rates are rapidly increasing. Although cesarean delivery is a life-saving surgical intervention, it can lead to adverse outcomes such as anxiety, decreased maternal satisfaction, and…
- Conditions
- Cesarean Section, Anxiety, Postoperative Period
- Trial name
- NCT07880587
- Testing
- Reflexology Hand Massage, Stroking Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Anesthesia; Reaction, Anesthesia
Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4
The goal of this clinical trial is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: Propofol or Dexmedetomidine.
- Trial name
- ICHOR (NCT07103616)
- Testing
- Randomization of Propofol or Dexmedetomidine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Hemodynamic Assessment, Bedside Ultrasonography
Assessment of LVOT VTI in Healthy Volunteers
Healthy subjects will have transthoracic echocardiography evaluation of Left Ventricular Outflow Tract Velocity-Time Integral (LVOT VTI) performed by operators after brief training.
- Conditions
- Hemodynamic Assessment, Bedside Ultrasonography, Point of Care Ultrasound (POCUS)
- Trial name
- NCT07600931
- Testing
- transthoracic echocardiography
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Caudal Block
Effects Of Adjuvants to Caudal Anesthesia on Hemodynamics Measured By Electrical Cardiometry In Children
Caudal epidural anesthesia is one of the most common regional techniques used for post-operative pain management in pediatric patients.
- Trial name
- NCT03101137
- Testing
- Caudal block with dexmedetomedine, Caudal dexamethasone, Control (bupivacaine)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Electroencephalography, Craniotomy Surgery
Evaluation of Response to Pain From Skull Pin Fixation in Craniotomies
The goal of this observational study is to investigate the relationship between the response to skull pin fixation pain and the analysis of blood pressure, heart rate, and brain wave activity in adults undergoing brain surgery.
- Conditions
- Electroencephalography, Craniotomy Surgery, Pain Management
- Trial name
- NCT06811701
- Testing
- Scalp nerve block, Opioid Anesthetics, Local Anesthetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Venous Insufficiency, Foot Drop (Acquired)
The Effect of Training on Hemodynamic Factors in Ballet Dancer
Classic ballet dance is a demonstration of complex motor skills to be revealed in aesthetic combinations and repetitively, and it demands intensive use of the lower extremities within extreme of range of motion (ROM).
- Trial name
- NCT04469361
- Testing
- Navicular drop measurement, Measurement of venous return parameters in supine, Measurement of venous return parameters in standing
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy Adults
Cross-validating the iTBS-induced Hemodynamic Response From fNIRS and fMRI: a Concurrent iTBS-fMRI-fNIRS Study
Intermittent theta-burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) is well established in treating patients with major depressive disorder (MDD).
- Trial name
- NCT06902571
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer's Disease
Memory Imaging of Normal Aging
The purpose of this study is to develop imaging techniques that can distinguish functional brain changes in people at high risk for dementia years prior to onset of clinical memory problems from those with normal changes of aging.
- Trial name
- NCT00315575
- Testing
- BOLD and Perfusion brain MRI
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Rupture of Membranes; Premature, Cesarean Section; Infection
The Effects of Labor Stages and Interventions on Hemodynamic Measures During & After Childbirth With Noninvasive Sensors
The Effects of Labor Stages and Interventions on Hemodynamic Measures During and After Childbirth ( Epidural, Rupture Membranses Cesarean Sections and Preeclampsia) With Noninvasive Sensors.
- Conditions
- Rupture of Membranes; Premature, Cesarean Section; Infection, Preeclampsia
- Trial name
- NCT03838965
- Testing
- biobeat sensor
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic
Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning
Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes .
- Conditions
- This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic, Maternal Positioning During CS
- Trial name
- NCT06857162
- Testing
- Positioninng during Cs
- Where
- Egypt
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Aswan University
Liver Failure
Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant
The purpose of this study is evaluate the medication vasopressin for its ability to preserve kidney function in patients undergoing liver transplantation.
- Trial name
- NCT00886262
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Fluid Responsiveness, Hemodynamics
Hemodynamic Evaluation and Fluid Response Observation Through Respiratory Maneuvers
This study evaluates whether respiratory maneuvers can induce measurable hemodynamic changes and whether these changes may be used to assess fluid responsiveness in healthy volunteers.
- Trial name
- HERO (NCT07840040)
- Testing
- Respiratory Maneuvers and Fluid Responsiveness Assessment Protocol
- Where
- Czechia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital Pilsen
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital