Clinical trials: Hemodynamics
Goal-Directed Fluid Therapy, Hemodynamic Monitoring
Comparison of Goal-directed and Liberal Fluid Management
Background: The investigators aim is to indicate that the "goal directed fluid management" is more effective for open abdominal surgeries by performing perioperative hemodynamic monitorisation using a minimal invasive pulse…
- Conditions
- Goal-Directed Fluid Therapy, Hemodynamic Monitoring, Fluid Management
- Trial name
- NCT04265014
- Testing
- Goal-directed fluid treatment, Liberal Fluid Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
HIE, TBI (Traumatic Brain Injury)
Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)
This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different…
- Conditions
- HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability
- Trial name
- ICHOR 1 (NCT06195345)
- Testing
- MR Imaging
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cesarean Section
To Compare the Effects of Oxytocin and Carbetocin on Intraoperative Hemodynamic Changes in Cesarean Section Surgeries.
To compare the effects of oxytocin and carbetocin, used as uterotonics in elective caesarean section surgeries, in terms of intraoperative hemodynamic changes.
- Trial name
- NCT06956365
- Testing
- Group-C, Group-O
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Histamine, Exercise
Histamines and Central Hemodynamics
When we exercise, more blood flow goes to our muscles, challenging our blood vessels. Following exercise, blood flow remains elevated and seems to be the reason for many of the positive cardiovascular benefits that occur with…
- Trial name
- NCT07285031
- Testing
- Diphenhydramine hydrochloride, Exercise Bout
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sodium Excess
Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics
High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who…
- Trial name
- NCT04233957
- Testing
- High Sodium
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Dental Anxiety, Impacted Mandibular Third Molar
Audiovisual vs Verbal Information in Third Molar Surgery
This study evaluates whether audiovisual (video-based) or verbal preoperative information is more effective in reducing dental anxiety and stabilizing physiological responses in patients undergoing impacted mandibular third molar…
- Trial name
- AVID (NCT07528755)
- Testing
- Audiovisual Information, Verbal Information
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Gazi University
Fatigue, Muscle
Feasibility Study of a Neuromuscular Fatigue Test and Associated Hemodynamic Responses: Application in Healthy Volunteers for Use in Patients with Chemotherapy-treated Breast Cancer
This cross-sectional and single-center study aims to progressively induce an increase in peripheral fatigue during successive efforts in healthy subjects.
- Conditions
- Fatigue, Muscle, Heart
- Trial name
- PROTECT-08A (NCT06775119)
- Testing
- Test of neuromuscular fatigue and associated hemodynamic responses
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut de cancérologie Strasbourg Europe
Exercise, Central Blood Pressure
Central Hemodynamic Exercise Responses Study
The purpose of this study is to examine the acute effect of continuous and aerobic interval exercise on postexercise central BP response in men with an elevated blood pressure.
- Trial name
- CHeER (NCT03118700)
- Testing
- Aerobic Interval Exercise, Continuous exercise
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cardiopulmonary Arrest
Infant Chest Compression
Pediatric cardiac arrest is an uncommon but critical life-threatening event requiring effective cardiopulmonary resuscitation (CPR). About 16,000 pediatric cardiac arrests occurs in the United States annually.
- Trial name
- NCT03004157
- Testing
- cardiopulmonary resuscitation
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Obstructive Sleep Apnea Syndrome
Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers
The goal of this trial is to assess the performance of the OxiplexTS-an absolute near-infrared oximeter-as an instrument to measure brain oxygenation and hemodynamics in sleep medicine as well as in the broader field of…
- Trial name
- NIRS-OSAS (NCT00591591)
- Testing
- OxiplexTS
- Where
- 4 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- ISS, Inc.
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Temperature Change, Body, Hypovolemia
Hemodynamic Effects of Cold Versus Warm Fluid Bolus
Fluid boluses are often administered with the aim of improving tissue perfusion in critically ill patients. It is unclear whether the temperature of the fluid has an impact on the hemodynamic response.
- Trial name
- NCT03209271
- Testing
- Ringer's Acetate (warm), Ringer's Acetate (cold)
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Hypoplastic Left Heart Syndrome
Near-infrared Spectroscopy (NIRS) Neurodevelopmental Outcomes
We believe that how a baby with Hypoplastic Left Heart Syndrome (HLHS)does after a major open heart operation, measured by things like blood pressure, oxygen saturation, heart rate and others, may have an impact on development.
- Trial name
- NIRS-ND (NCT00464100)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Healthy Volunteers
Influence on Erythropoetin-level by Xenon
The purpose of this study is to analyze the effect of xenon-inhalation on erythropoetin-level in blood of healthy volunteers and to determine the efficient time of inhalation.
- Trial name
- XEPO (NCT02129400)
- Testing
- Xenon pro Anaesthesia 100 % (V/V), Aer medicinalis Linde 100%
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Hemodynamic Instability
The Colder Fluids - Intravenous Infusion of 10 Degrees Celsius Fluids and Its Effects on Circulation and Hemostasis
The aim of this study is to investigate the effect of respectively 10 and 22 degrees Celsius Ringer's lactate solution on the physiological response in healthy adults.
- Trial name
- NCT06622499
- Testing
- Ringer's Lactate
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Intubation, Intratracheal
Response to Endotracheal Tube Intubation at Different Time of Fentanyl Given During Induction
Opioids have been used to modify the hemodynamic response associated with laryngoscopy and tracheal intubation. To seek the correlation of Fentanyl given time, we will analysis the data collected from vital signs monitoring…
- Trial name
- NCT03728686
- Testing
- Different given time
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Chien-Chung,Huang
Menopause, Cardiovascular Risk Factor
Effect of 4 Weeks of Citrulline and Glutathione Supplementation on Arterial Function
Examining the effects of 4 weeks of Citrulline alone or in combination with glutathione on the arterial function of postmenopausal women.
- Trial name
- NCT04672447
- Testing
- L-Citrulline, Glutathione
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Cesarean Section Complications
Intrathecal Bupivacaine-fentanyl and Bupivacaine-dexmedetomidine for Elective Low Segment Caesarean Section
the primary objective of the study is to compare the onset and recovery times of sensory and motor blockade of the two study drugs intrathecally with low dose bupivacaine The secondary objectives of the study are to observe…
- Trial name
- NCT04095013
- Testing
- Bupivacaine, fentanyl, Bupivacaine, dexmedetomidine
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences