Clinical trials: Hemodynamics
Hypovolemia, Fluid Loss
Acetated Ringer´s Solution in Experimental Hypovolemia
Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over…
- Conditions
- Hypovolemia, Fluid Loss, Hemodynamic Instability
- Trial name
- Volu-Flow (NCT05705115)
- Testing
- Ringer acetate, Lower body negative pressure
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hemodynamic Assessment, Bedside Ultrasonography
Assessment of LVOT VTI in Healthy Volunteers
Healthy subjects will have transthoracic echocardiography evaluation of Left Ventricular Outflow Tract Velocity-Time Integral (LVOT VTI) performed by operators after brief training.
- Conditions
- Hemodynamic Assessment, Bedside Ultrasonography, Point of Care Ultrasound (POCUS)
- Trial name
- NCT07600931
- Testing
- transthoracic echocardiography
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Prefrontal Hemodynamics, Muscle Strength
Lower Limb Strength and Power as Predictors of Brain Blood Flow During Exercise
This study aims to investigate the predictive value of lower limb muscle strength and explosive power on exercise-induced prefrontal hemodynamic responses.
- Conditions
- Prefrontal Hemodynamics, Muscle Strength, Physical Performance
- Trial name
- LLSPP (NCT07575802)
- Testing
- Standardized Lower-Limb Physical Performance Assessment and Aerobic Exercise Task
- Where
- Russia
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Breast Cancer, Breast Surgery
Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia
This prospective observational study aims to evaluate the effects of intradermal methylene blue injection on intraoperative hemodynamic stability in patients undergoing breast surgery under general anesthesia.
- Conditions
- Breast Cancer, Breast Surgery, Sentinel Lymph Node Biopsy, Methylene Blue
- Trial name
- NCT07040540
- Testing
- Methylene Blue, Standard Surgical Care Without Dye
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
HIE, TBI (Traumatic Brain Injury)
Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)
This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different…
- Conditions
- HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability
- Trial name
- ICHOR 1 (NCT06195345)
- Testing
- MR Imaging
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Blood Pressure, Hemodynamic Response
Ischemic Preconditioning in Resistance Exercise in Older Women
This study investigates whether ischemic preconditioning (IPC) can reduce cardiac demand after resistance exercise in older women.
- Conditions
- Blood Pressure, Hemodynamic Response, Rating of Perceived Exertion, Heart Rate
- Trial name
- NCT07497659
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Laryngoscopy, Hemodynamic Changes
Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of Laryngoscopy
Participants will undergo routine pre-operative evaluation. An intravenous line will be placed in the recovery area. On arrival in the operating room, standard monitoring (blood pressure, heart rate, oxygen saturation, ECG…
- Trial name
- NCT07435337
- Testing
- Nalbuphine, Fentanyl
- Where
- Pakistan
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Institute of Cardiology
Hemodynamic Changes, Music Therapy
Effects of Music Therapy on Anesthetic Requirements and Hemodynamic Parameters
Music therapy has been reported to reduce analgesic and anesthetic requirements, but evidence in thoracic surgery remains limited.
- Conditions
- Hemodynamic Changes, Music Therapy, Thoracic Surgery, Anesthetic Consumption
- Trial name
- NCT07322562
- Testing
- music therapy during surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pregnancy Related, Heart Rate Variation (HRV)
Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.
Heart rate variability (HRV) provides a non-invasive assessment of autonomic control of the nervous system over the heart. During pregnancy, the cardiovascular system adapts significantly, affecting HRV and hemodynamics.
- Conditions
- Pregnancy Related, Heart Rate Variation (HRV), Hemodynamics
- Trial name
- EMMA (NCT07376616)
- Testing
- Assessment of HRV and blood pressure
- Where
- Spain
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Maternity, Pregnancy
Passive Leg Raising in Term Pregnancy on Hemodynamic Monitoring - Validating With Transthoracic ECHO (LG-ECHO)
This prospective observational validation study aims to evaluate the agreement and diagnostic accuracy of ClearSight™ compared with transthoracic echocardiography (TTE) during PLR in term pregnant women.
- Conditions
- Maternity, Pregnancy, Labor and Delivery, Hemodynamic Changes
- Trial name
- (LG-ECHO) (NCT07253818)
- Testing
- ClearSight™ System, Transthoracic Echocardiography, Passive Leg Raising (PLR) Maneuver
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ayse Zeynep Turan Civraz
Hemodynamic Measure, Cognitive Performance in Healthy Volunteers
Assessing the Impact of High Theacrine Doses on Hemodynamic Measures
This project measured physiological and cognitive variables to determine the effectiveness of Theacrine (TCR) as a stimulant at doses greater than those previously tested.
- Trial name
- NCT07376564
- Testing
- Low dose theacrine, Medium dose theacrine, High dose theacrine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Titch Madzima
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hypovolemia, Hemodynamic Instability
Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia
To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.
- Trial name
- LBPN (NCT03592290)
- Testing
- Lower body negative pressure
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiac Autonomic Function, Hemodynamic Changes
Effects of Post-Match Foam Rolling, Static Stretching, and Passive Rest on Acute Cardiac-Autonomic, Hemodynamic, and Neuromuscular Recovery in National Wrestlers
This study looks at three common ways athletes recover after a wrestling match: foam rolling, static stretching, and resting. We want to learn which method helps the body recover better in the short time that athletes often have…
- Conditions
- Cardiac Autonomic Function, Hemodynamic Changes, Neuromuscular Adaptations, Exercise and Recovery
- Trial name
- NCT07305506
- Testing
- Foam Rolling, Static Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ali Kamil GÜNGÖR
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anxiety, Hemodynamic Instability
Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety Level
This randomized controlled study evaluates the effect of acupressure application on the anxiety level patients undergoing cystectomy surgery.
- Trial name
- NCT05325307
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Vascular Remodeling, Sedentary Behavior
Effect of Training Intensity on Microvascular Function
The aim of this trial is to investigate the effect of aerobic training intensity on muscle vascular function: continuous versus interval.
- Conditions
- Vascular Remodeling, Sedentary Behavior, Hemodynamic Rebound
- Trial name
- NCT07237854
- Testing
- Percutaneous muscle biopsies of the vastus lateralis (quadriceps), Measurement of the maximal oxygen uptake (VO2max), Non-Invasive Cardiac Output Measurement (Innocor)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Perioperative Anxiety, Perioperative Pain Management
Evaluation of the Effectiveness of Virtual Reality as an Adjunct to Standard Care in Managing Perioperative Anxiety and Pain in Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
The goal of this clinical trial is to evaluate whether virtual reality (VR) can effectively reduce perioperative anxiety and pain in patients undergoing lower limb orthopedic surgery under spinal anesthesia.
- Conditions
- Perioperative Anxiety, Perioperative Pain Management, Hemodynamic Stability, Satisfaction
- Trial name
- NCT07134764
- Testing
- Virtual reality session
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Pain, Comfort Theory
The Effect of Nursing Care Based on Kolcaba's Comfort Theory on the Newborn
It was planned to determine the effect of nursing care based on Kolcaba's Comfort Theory on newborns' comfort, pain and hemodynamic variables for babies admitted to the neonatal intensive care unit.
- Conditions
- Pain, Comfort Theory, Hemodynamic Variables
- Trial name
- NCT06491641
- Testing
- Care based on Kolcaba's comfort theory
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cukurova University