Clinical trials: Hemodynamic Instability
Acute Myocardial Infarction
Clopidogrel Efficacy and Acute Coronary Syndromes
The purpose of this study is to compare clopidogrel effectiveness between severe hemodynamically unstable versus stable patients with acute myocardial infarction.
- Trial name
- NCT00839267
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Charles University, Czech Republic
Malignant Ascites, Ovarian Cancer
Malignant Ascites in Ovarian Cancer: Impact of Total Paracentesis on Hemodynamics
The ATLANTIS-study was designed to determine the safety of a full paracentesis in patients with malignant ascites due to ovarian cancer.
- Conditions
- Malignant Ascites, Ovarian Cancer, Hemodynamic Instability
- Trial name
- ATLANTIS (NCT04032600)
- Testing
- Paracentesis
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Charite University, Berlin, Germany
Perioperative Complication, Hemodynamic Instability
The Influence of Fasting on Selected Hemodynamic Parameters Measured in a Non-invasive Way
Preoperative fasting is considered to be refraining from taking meals for at least 6 hours and clear fluids for at least 2 hours before anesthesia.
- Trial name
- NCT04972500
- Testing
- Nutricia Pre-op, 400 milliliters, per os
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Anxiety, Hemodynamic Instability
Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety Level
This randomized controlled study evaluates the effect of acupressure application on the anxiety level patients undergoing cystectomy surgery.
- Trial name
- NCT05325307
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Hemodynamic Instability
Hemodynamic Effects of Continuous Spinal Anesthesia in Patient Aged Over 65 Years
Compared to single-dose spinal anesthesia, continuous spinal anesthesia using small titrated doses of local anesthetic, was safe, efficient and provided better hemodynamic profile in elderly patients.
- Trial name
- NCT03195166
- Testing
- FloTrac sensor/Vigileo
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- University Tunis El Manar
Vascular Stiffness, Hypotension on Induction
The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia
Arterial hypotension during induction of general anesthesia is a risk factor for developing postoperative cardiovascular complications.
- Conditions
- Vascular Stiffness, Hypotension on Induction, Anesthesia; Reaction
- Trial name
- NCT03237429
- Testing
- bioimpedance spectroscopy
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Liver Transplantation, Shock
Hemodynamic Profiles and Macro-Microcirculatory Coherence in Liver Transplantation: an Integrative Approach in the Immediate Postoperative Period
Hemodynamic instability is a common and serious condition in patients undergoing liver transplantation and is associated with increased morbidity and mortality if not promptly recognized and treated.
- Conditions
- Liver Transplantation, Shock, Hemodynamic Instability
- Trial name
- COHERENCE-LT (NCT07547020)
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hospital El Cruce
Hemodynamic Instability, Patient Satisfaction
Efficacy of Ultrasound Guided Erector Spinae Plane Block
Thoracic epidural and paravertebral blocks are the most widely regional technique used for postoperative analgesia after surgery, but they are difficult to perform and carry a risk of serious complication.
- Conditions
- Hemodynamic Instability, Patient Satisfaction, Postoperative Pain, Regional Block
- Trial name
- NCT04371705
- Testing
- Erector spinae plane block, control
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Minia University
Hemorrhagic Shock
Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans
The purpose for this study is to measure the physiology of human undergoing a Lower Body Negative Pressure usea non-invasive low-power optical technique, near-infrared diffuse optical spectroscopy measurement and compare these…
- Trial name
- NCT00581204
- Testing
- Near-Infrared Diffuse Optical Spectroscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hemodynamic Instability During Anesthesia, High Risk Surgery
Focused TTE for Hemodynamic Instable High Risk Patients
Focused transthoracic echocardiography (TTE) is a technique, which allows quick and non-invasive diagnosis and monitoring in hemodynamic instable patients.
- Trial name
- NCT01811914
- Testing
- intraoperative TTE
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Philipps University Marburg
Hemodynamic Instability, Postoperative Complications
Continuation of Goal Directed Haemodynamic Optimization in the PACU
Post-operative monitoring of all patients after anaesthesia in the post anaesthesia care unit (PACU) is standard of care today. It helps to reduce morbidity and even mortality in high-risk patients.
- Conditions
- Hemodynamic Instability, Postoperative Complications, Ultrasound Imaging
- Trial name
- NCT04822116
- Testing
- goal directed intraoperative haemodynamic optimization
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Critical Illness, Sepsis
Physiological Effects of 38°C vs. 22°C Fluid Therapy in Critically Ill Patients
A randomized controlled clinical trial. 24 adult ICU patients will be recruited upon decision to administer fluid bolus of 500ml of crystalloid.
- Conditions
- Critical Illness, Sepsis, Fluid Overload, Hemodynamic Instability
- Trial name
- NCT04576806
- Testing
- Body temperature, Fluid bolus, Room temperature
- Where
- 2 sites in Sweden
- Sponsor
- Karolinska Institutet
Hemodynamic Instability
Intra-Osseous Access in Difficult Vascular Access Cases
Thousands of peripheral venous accesses are inserted every day all over the world. Some of them, such as those inserted in emergency and / or in critical patients, are absolutely vital.
- Trial name
- IODA (NCT05708833)
- Testing
- Intraosseous venous access, Peripheral venous access
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hemorrhagic Strokes, Postoperative Hypertension
A Comparison of Nicardipine and Labetalol for Blood Pressure Control in Intensive Care Patients After Hemorrhagic Stroke Brain Surgery
Patients with hemorrhagic stroke who undergo brain surgery (craniotomy) often experience high blood pressure after surgery. Poor blood pressure control can increase the risk of bleeding, brain injury, and other serious…
- Conditions
- Hemorrhagic Strokes, Postoperative Hypertension, Hemodynamic Instability
- Trial name
- NIC-LAB ICU (NCT07364201)
- Testing
- Nicardipine, Labetalol
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sumatera Utara
Acute Heart Failure, Low Cardiac Output Syndrome
Exogenous Ketones for Acutely Decompensated HEart Failure
This study will evaluate whether supplementation of exogenous ketones in patients with severe left ventricular dysfunction and acutely decompensated heart failure requiring inotropic therapy would improve the patient's…
- Conditions
- Acute Heart Failure, Low Cardiac Output Syndrome, Hemodynamic Instability, Ketosis
- Trial name
- KADHEF (NCT04698005)
- Testing
- 25g Ketone monoester without added salts
- Where
- Czechia
- Volunteers
- 24 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Stroke, Ischemic, Stroke/Brain Attack
Manually Controlled Infusion Vs Target Controlled Infusion for StrokeThrombectomy
The goal of this randomized controlled trial is to compare manual general anesthesia induction to general anesthesia induction guided by target controlled infusion system in cerebral ischemic stroke The main questions it aims to…
- Conditions
- Stroke, Ischemic, Stroke/Brain Attack, Anesthesia, Hemodynamic Instability
- Trial name
- HASTE (NCT05570682)
- Testing
- TCI, Manual induction
- Where
- Italy
- Sponsor
- University of Padova
Hemodynamic Instability, Pain
Evaluation in 15 Participants of Blood Flow, Comfort and Efficiency, Using 1 vs 36 Hz Stimulation Via Textile Electrodes
Muscle contractions induced by calf low-intensity neuromuscular electrical stimulation (C-LI-NMES) can increase venous return and may reduce venous thromboembolism.
- Trial name
- TTE_PVV_1_36 (NCT06082297)
- Testing
- Chattanooga Physio, DJO, neuromuscular electrical stimulation
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Hemodynamic Instability, Disorder of Oxygen Transport
Walking the Isobole of Drug Interaction
The investigators study whether four equipotent combinations of propofol and remifentanil (as predicted by interaction models for "tolerance of laryngoscopy") result in identical haemodynamic conditions, independent of their…
- Conditions
- Hemodynamic Instability, Disorder of Oxygen Transport, Interaction, Anesthesia
- Trial name
- Walibi (NCT02067936)
- Testing
- Group A propofol + remifentanil, Group B propofol + remifentanil, Group C propofol + remifentanil
- Where
- Netherlands
- Volunteers
- 87 people
- Sponsor
- University Medical Center Groningen
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd