Clinical trials: Hemodynamic
AKI - Acute Kidney Injury, Cardiac Surgery
Urine Output Response to Fluid and Diuretic Therapy in Cardiac ICU Patients Monitored With FIZE kUO®
This prospective observational study evaluates the real-time urine output response to fluid therapy and diuretics in cardiothoracic intensive care unit (CTICU) patients monitored with the FIZE kUO® device.
- Conditions
- AKI - Acute Kidney Injury, Cardiac Surgery, Fluid Therapy, Hemodynamic Instability
- Trial name
- NCT07022314
- Testing
- FIZE kUO®
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- FIZE Medical ltd
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Hemodynamic Instability
Preoperative Ivabradine Doses for Hemodynamic Stability in FESS
This study compares two different preoperative doses of a heart-rate-lowering medication called ivabradine in patients undergoing endoscopic sinus surgery under general anesthesia.
- Trial name
- NCT07797946
- Testing
- Ivabradine 5 mg/5 mg regimen, Ivabradine 5 mg/7.5 mg regimen
- Volunteers
- 60 people
- Sponsor
- Minia University
Hemodynamic (MAP) Stability
Effect of Adding a Low-Dose Epinephrine Bolus Prior to Infusion on Maternal Hemodynamic Stability During Cesarean Section
In North America, norepinephrine, ephedrine, and epinephrine have been recommended as first-choice vasopressors for the treatment of spinal hypotension during cesarean delivery.
- Trial name
- NCT07480889
- Testing
- Epinephrine (Adrenaline) bolus then infusion, Epinephrine (Adrenaline) infusion
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Spinal Anesthesia, Hemodynamic Changes
Hemodynamic Effects of Bilateral and Unilateral Spinal Anesthesia Using the Continuous Pressure Recording Analytical Method.
This randomized controlled study aims to compare the intraoperative hemodynamic effects of unilateral and bilateral spinal anesthesia in elderly patients undergoing elective total hip arthroplasty.
- Trial name
- NCT07789795
- Testing
- Unilateral Spinal Anesthesia, Bilateral Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kayseri City Hospital
Aging, Autonomic Nervous System
Effects of a Smart Circuit Exercise Program on Health Outcomes in Community-Dwelling Older Adults
This study was conducted in collaboration with a community-based retirement facility to evaluate the clinical effectiveness of a smart, technology-assisted circuit exercise intervention for community-dwelling older adults.
- Conditions
- Aging, Autonomic Nervous System, Hemodynamics
- Trial name
- NCT07790263
- Testing
- Smart Circuit Exercise Program
- Where
- Taiwan
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hemodynamic Instability
HemoSphere Alta Study
A prospective, non-randomized single arm study using the HemoSphere Alta Advanced Monitoring Platform and associated devices in adult subjects.
- Trial name
- NCT07148323
- Testing
- HemoSphere Alta Monitor, Swan-Ganz IQ pulmonary arterial catheter, ForeSight IQ Large sensor, and Acumen IQ sensor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Becton, Dickinson and Company
Hemorrhage, Hemodynamic Instability
Consortium for Optimized Integration of Bio-Artificial Blood Components for Adaptive Resuscitation Therapy
There is need for a whole blood analog for use when banked blood is unavailable or undesirable. In civilian trauma, hemorrhage accounts for ~ 35% of pre-hospital deaths; moreover, ~ 20% of military casualties are in hemorrhagic…
- Trial name
- CONCERT (NCT05756426)
- Testing
- Prospective
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hemodynamic Response to Laryngoscopy and Orotracheal Intubation
Effect of Nalbuphine on Hemodynamic Response During Laryngoscopy and Intubation
Laryngoscopy and placement of a breathing tube during general anesthesia can cause temporary increases in blood pressure and heart rate. These changes may be harmful in some patients.
- Trial name
- NAL-HRI (NCT07348159)
- Testing
- Normal saline IV, Nalbuphine 0.2 mg/kg
- Where
- Pakistan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Dr. Waseem Ullah
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Hemodynamic Responses to Laryngoscopy and Tracheal Intubation
Laryngoscopy and tracheal intubation lead to tachycardia and hypertension due to increase in the plasma catecholamines subsequent to sympathetic stimulation.
- Trial name
- NCT07783256
- Testing
- ketodex, ketofol
- Volunteers
- 70 people
- Sponsor
- Assiut University
Venous Hemodynamics
Effects of Positive End-Expiratory Pressure (PEEP) and Prone Positioning in Healthy Volunteers on Venous Hemodynamics Including the Venous Excess Ultrasound (VExUS) Score
The hemodynamic effects of proning and PEEP may vary depending on pre- existing cardiac function, lung mechanics, and volume status, and the available evidence remains conflicting.
- Trial name
- VeNIVPro (NCT07273617)
- Testing
- application of PEEP: starting PEEP = 15 mbar, application of PEEP: starting PEEP = 0 mbar
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Tracheal Intubation, Anesthesia, General
ED90 of Tegileridine for Suppressing Hemodynamic Response to Tracheal Intubation: A Biased Coin Up-and-Down Trial
General anesthesia tracheal intubation causes sympathetic activation and hemodynamic stress response, which increases perioperative cardiovascular risk, especially in elderly subjects.
- Conditions
- Tracheal Intubation, Anesthesia, General, Hemodynamics
- Trial name
- NCT07749131
- Testing
- Tegileridine
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Shiyou Wei
Pancreas Disease, Troponin T
Cardiac Cycle Efficiency and Postoperative Troponin
Knowing how intraoperative anesthesia management and cardiac cycle monitoring affect postoperative cardiac outcomes in patients undergoing pancreatic surgery can help develop a protocol for future cases.
- Conditions
- Pancreas Disease, Troponin T, Hemodynamic Monitoring, MINS
- Trial name
- NCT07778914
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul Saglik Bilimleri University
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min.
- Trial name
- NCT07670923
- Testing
- Propofol Injection, Ciprofol Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- General Hospital of Ningxia Medical University
Vascular Access, Elevated Jugular Venous Pressure
Ultrasound Assessment of Internal Jugular Vein for Cannulation and Venous Pressure Prediction
This prospective observational study aims to evaluate the diagnostic utility of vascular ultrasound for internal jugular vein (IJV) assessment in adult patients undergoing clinically indicated IJV cannulation.
- Conditions
- Vascular Access, Elevated Jugular Venous Pressure, Hemodynamic Instability
- Trial name
- NCT07773506
- Volunteers
- 100 people
- Sponsor
- Assiut University
Circulatory Shock, Hemodynamic Instability
Peripheral pULSe Assessment and Arterial pRessure (PULSAR)
This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending…
- Conditions
- Circulatory Shock, Hemodynamic Instability, Hypotension, Shock
- Trial name
- PULSAR (NCT07609095)
- Testing
- Peripheral Pulse Palpation
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Region Stockholm
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
ECT, Electroconvulsive Therapy
Virtual Reality to Reduce Pre-procedure Anxiety Prior ECT
Lack of patient knowledge about ECT (electroconvulsive therapy) is a leading cause of treatment fear with 60% of ECT patients reporting high levels of anxiety.
- Conditions
- ECT, Electroconvulsive Therapy, Virtual Reality, Anxiety
- Trial name
- PERFECT-VR (NCT04291196)
- Testing
- VR-ECT 360o Video, Standard Treatment
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Hemodynamic Changes
Effect of Stress Ball During Chest Tube Removal After Open Heart Surgery
15 minutes before the procedure, nurses (FEÖ and NT) will explain and demonstrate how to use the stress ball. The stress ball will be applied for approximately five minutes, including the chest tube removal procedure.
- Conditions
- Pain, Hemodynamic Changes, Anxiety
- Trial name
- Stress ball (NCT07251270)
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Mersin University
Anesthesia Recovery Period ； Postoperative Pain； Hemodynamic Stability During Surgery
Afentanil and Remifentanil for Anesthesia Quality and Recovery
The goal of this clinical trial is to compare two commonly used opioid pain medications-alfentanil and remifentanil-during general anesthesia for surgery, and to find out whether alfentanil is as good as (not worse than)…
- Trial name
- NCT07761312
- Testing
- alfentanil, Remifentanil
- Volunteers
- 990 people
- Sponsor
- Qianfoshan Hospital