Clinical trials: Hemodialyzed Patients
Chronic Renal Failure, Chronic Kidney Disease
A Phase 3 Study Comparing the Effects of Subcutaneous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of this study is to demonstrate therapeutic equivalence of subcutaneous (SC) Epoetin Hospira compared to SC Epogen (Amgen), based on maintenance of hemoglobin (Hb) levels and study drug dose requirements in patients…
- Trial name
- AiME - 13 (NCT01473420)
- Testing
- Epoetin Hospira, Epogen Amgen
- Where
- 73 sites in United States
- Volunteers
- 320 people
- Sponsor
- Pfizer
Chronic Kidney Disease, Hemodialysis
Nicotinamide in Hemodialysis Patients With Hyperphosphatemia
Study hypothesis: Nicotinamide inhibits gastrointestinal phosphate absorption and serum phosphate levels of dialysis patients in a dose dependent manner.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Hyperphosphatemia
- Trial name
- DONATO (NCT01200784)
- Testing
- Nicotinamide
- Where
- 36 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Chronic Kidney Disease Requiring Chronic Dialysis, Hemodialysis, Home
Body Composition Monitor Among Daily Home Dialysis With Low Flow Dialysate
The fluid overload measured by the Body Composition Monitor (BCM Fresenius Medical Care) is a new independent risk factor of mortality.
- Conditions
- Chronic Kidney Disease Requiring Chronic Dialysis, Hemodialysis, Home, Electric Impedance
- Trial name
- VOLODIA (NCT03994133)
- Testing
- Measurement of the hydration state by bio-impedance spectroscopy
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Caen
COVID-19
Thymosin Alpha 1 to Prevent COVID-19 Infection in Renal Dialysis Patients
Thymalfasin (thymosin alpha 1 or Ta1), the active pharmaceutical ingredient in ZADAXIN® injection, is a 28-amino acid synthetic peptide, identical to natural Ta1 produced by the thymus gland.
- Trial name
- Ta1 (NCT04428008)
- Testing
- Thymalfasin
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- William B. Ershler, MD
Hemodialysis Patients
Prevalence of Fatigue in Hemodialysis Patients
The prevalence of end stage renal disease in Taiwan was listed first all over the world. Fatigue, which makes patients unable to be competitive to play their functional roles, is one of the most bothersome symptoms of patients…
- Trial name
- NCT01846754
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- National Taiwan University Hospital
Hemodialysis Patients
The Effect of Horticultural Therapy on Stress, Well-Being, and Care Burden in Hemodialysis Caregivers
This research is a randomized controlled single-blind experimental study aiming to evaluate the effect of horticultural therapy on stress, well-being, and caregiver burden among caregivers of hemodialysis patients.
- Trial name
- NCT07188792
- Testing
- HORTICULTURAL THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Acute Kidney Injury
IHD Versus CRRT for Severe Acute Kidney Injury in Critically Ill Patients
Intermittent hemodialysis (IHD) and continuous RRT (CRRT) provided as continuous hemofiltration or hemodiafiltration are the main RRT modalities in ICU.
- Trial name
- ICRAKI (NCT06032884)
- Testing
- continuous renal replacement therapy (CRRT), Intermittent hemodialysis (IHD)
- Where
- France
- Volunteers
- 554 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
End Stage Renal Disease on Dialysis
Assessment of D-dimer and CRP for Cardiovascular Risk Prediction in Hemodialysis Patients
This study aims to assess whether two blood markers - C-reactive protein (CRP) and D-dimer - can help predict cardiovascular complications in patients undergoing regular hemodialysis.
- Trial name
- BIOCARD-HD (NCT07130721)
- Testing
- C-Reactive Protein (CRP) Test, D-dimer Test, Electrocardiogram (ECG)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Hemodialysis Patients, Caregivers of Chronic Hemodialysis Patients
SeroCOVIDial Study: Assessment of COVID-19 Seroconversion in Patients on Chronic Hemodialysis and in Their Caregivers, a Cohort Study
Background: The preventive containment measures implemented in the COVID-19 pandemic are not feasible in chronic hemodialysis patients (HD) who need to attend their dialysis sessions 3 times a week.
- Trial name
- SeroCOVIDial (NCT04420338)
- Testing
- Blood sample, Serum tube collection
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Hemodialysis Complication
A Study of Compound Amino Acid Capsule on Maintenance Hemodialysis Patients
The goal of this retrospective cohort study is to investigate the effects of compound amino acid capsule on nutrition, calcium and phosphorus metabolism in maintenance hemodialysis(MHD) patients.
- Trial name
- NCT05874557
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Kidney Failure, Chronic, Renal Dialysis
Renal Denervation in End Stage Renal Disease Patients With Refractory Hypertension
The purpose of this this study is to investigate the clinical utility of renal denervation in the treatment of ESRD patients with refractory hypertension.
- Trial name
- NCT00753116
- Testing
- Renal Denervation with a catheter-based procedure
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medtronic Vascular
Hemodialysis Complication
The Effect of Patient Education Based on Nursing Model on Life Activities and Self-Care of Hemodialysis Patients
Chronic Renal Failure (CRF); The result of a decrease in the glomerular filtration value is defined as a chronic and progressive deterioration in the fluid-solute balance of the kidney and metabolic-endocrine functions.
- Trial name
- NCT04797234
- Testing
- Control, Experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Hyperphosphatemia
Nicotinic Acid in Hemodialysis Patients With Hyperphosphatemia
With calcium carbonate as the positive control drug, to observe the effectiveness and safety of nicotinic acid in hemodialysis patients with hyperphosphatemia
- Trial name
- NAHPH (NCT02836184)
- Testing
- Nicotinic Acids, Calcium Carbonate
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Jiujiang No.1 People's Hospital
Sarcopenia
the Effect of Exercise and Oral Supplement Intervention in Sarcopenia Markers in Hemodialysis Patients
Objective: To assess the effect of different post-exercise oral nutritional supplement intake timing on sarcopenia indicators in hemodialysis patients.
- Trial name
- NCT05809219
- Testing
- 1 hour combined intervention ( Exercise and nutrition), 3 hours combined intervention ( Exercise and nutrition), Nutrition intervention
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- China Medical University Hospital
Hepatitis B
Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years
Comparison of adjuvanted hepatitis B vaccine to double dose of Engerix™-B in pre- /haemodialysis patients aged ≥15 years.
- Trial name
- NCT00383383
- Testing
- Hepatitis B adjuvanted vaccine, Engerix-B
- Where
- 3 sites in Czechia, Malaysia and 1 more
- Volunteers
- 141 people
- Sponsor
- GlaxoSmithKline
Patients With Impaired Renal Function and Haemodialysis
ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis
The objective of this study is to evaluate the pharmacokinetics and safety of ASP8825 in patients with impaired renal function and haemodialysis.
- Trial name
- NCT02629224
- Testing
- ASP8825
- Where
- 2 sites in Japan
- Volunteers
- 18 people
- Sponsor
- Astellas Pharma Inc
Hemodialysis
Efficacy and Tolerance of RHEOpheresis in the Treatment of Peripheral Artery Disease in Hemodialysis Patients
Peripheral arterial disease (PAD) with limb-threatening ischemia (PAD-LTI) involves both macrocirculation and microcirculation. Macrocirculatory abnormalities are accessible to revascularization techniques (endovascular or…
- Trial name
- RHEO-PAD (NCT03975946)
- Testing
- Rheopheresis procedure, Blood Sample
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Potassium Imbalance, Cardiac Arrhythmia
The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)
This study is a multicenter, prospective and randomized controlled study. The experiment includes a 1-week screening period (1 week before dialysis) and a 7-week treatment period (1-4 weeks of dose drip period and 5-7 weeks of…
- Conditions
- Potassium Imbalance, Cardiac Arrhythmia, Dialysis; Complications
- Trial name
- NCT06242041
- Testing
- sodium zirconium cyclic silicate
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Peking University First Hospital
End-stage Renal Disease, Malnutrition; Protein
Impact of IDPN on Nutrition Markers in Patients Receiving ICHD
Evaluate the impact of intradialytic parenteral nutrition (IDPN) compounded with Clinisol, Prosol, and/or Clinolipid on albumin levels and weight in patients with end-stage renal disease (ESRD) undergoing in-center hemodialysis.
- Trial name
- NCT05439174
- Testing
- Intradialytic Parenteral Nutrition
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Patient Care America
Anemia
Ferumoxytol Versus Oral Iron in the Treatment of Anemia in Hemodialysis Patients
The study will evaluate the safety and efficacy of a new intravenously administered iron drug to treat anemia in patients on hemodialysis.
- Trial name
- NCT00233597
- Testing
- ferumoxytol or oral iron
- Where
- 50 sites in United States
- Volunteers
- 230 people
- Sponsor
- AMAG Pharmaceuticals, Inc.