Clinical trials: Hemodialysis Patients
End Stage Renal Disease, Hemodialysis
Immune Effects of Vitamin D in Hemodialysis Patients
The purpose of this study to examine whether vitamin D can reduce the activation of the immune system during dialysis. When activated, the immune cells release certain substances, called cytokines, which can be measured from…
- Conditions
- End Stage Renal Disease, Hemodialysis, Inflammatory Response, Cardiovascular Disease
- Trial name
- NCT00686751
- Testing
- paricalcitol
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Renal Research Institute
Staphylococcus Aureus
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of AZD7760 when given as an intravenous infusion to healthy participants (Phase I) or participants with end-stage kidney disease receiving hemodialysis…
- Trial name
- PEAK (NCT06749457)
- Testing
- AZD7760
- Where
- 40 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Hyperphosphatemia, End-stage Renal Disease
A Safety and Tolerability Study of Zerenex (Ferric Citrate) in Patients With End-Stage Renal Disease (ESRD)
This study is to evaluates the safety and tolerability of Zerenex™ (ferric citrate) as a treatment for hyperphosphatemia in patients with End-Stage Renal Disease.
- Trial name
- NCT00648167
- Testing
- ferric citrate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Keryx Biopharmaceuticals
Chronic Renal Failure
Docohexanoic Acid in Hemodialysis Patients
Docohexanoic acid (DHA), a dietary n-3 polyunsaturated fatty-acid omega-3 (n-3, PUFA), showed potential beneficial effects in reducing all-cause mortality in hemodialysis (HD) patients.
- Trial name
- NCT04536636
- Testing
- Docohexanoic acid, Control-No drug
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
End Stage Renal Disease, Haemodialysis
Combination of Medium Cut-off Dialyzer Membrane and Diet Modification to Alleviate Residual Uremic Syndrome of Dialysis Patients
The study will compare achieved levels of protein-bound uremic toxins with dialysis using a medium cut-off membrane compared to the treatment by online haemodiafiltration with a high-flux dialysis membrane.
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy
- Trial name
- NCT04247867
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium and Inulin), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
Renal Failure
Music Interventions for Patients Undergoing Hemodialysis
Fatigue is found to be one of the most persistent problems among patients in treatment with hemodialysis, and associated with impaired health-related quality of life.
- Trial name
- NCT04959682
- Testing
- Music Intervention
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Southern Denmark
Chronic Kidney Disease Requiring Chronic Dialysis
Intradialytic Resistance Training in Haemodialysis Patients
The study will investigate the effects of an intradialytic resistance training on miRNA´s expression and muscle strength in haemodialysis patients.
- Trial name
- IRTHEP (NCT03511924)
- Testing
- Intradialytic resistance training
- Where
- Slovakia
- Volunteers
- 90 people
- Sponsor
- Pavol Jozef Safarik University
Oxidative Stress, Inflammation
CoQ10 Biomarker Trial
The investigators believe that relieving the oxidative stress experienced by hemodialysis patients may help improve cardiovascular health.
- Conditions
- Oxidative Stress, Inflammation, Endothelial Dysfunction
- Trial name
- NCT01408680
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Washington
Thromboelastography, Hemodialysis
Preliminary Exploration of Thromboelastography in the Monitoring of Anticoagulation in Maintenance Hemodialysis Patients
Objectives: To investigate the role of thromboelastography parameters (R, K, Angle, MA) in monitoring anticoagulation in maintenance hemodialysis (MHD) patients. Subjects: Two hundred stable MHD patients.
- Conditions
- Thromboelastography, Hemodialysis, Anticoagulation
- Trial name
- NCT06272708
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration
Catheter Dysfunction Rate in Patients Undergoing Kidney Replacement Therapy. Evaluation of the Safety and Efficacy of Anti-reflux Valves Without Heparin Lock Solution
Catheter dysfunction and infections are the most common complications observed among patients with dialysis catheters for long-term dialysis ( CDLD ) .
- Conditions
- Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration, Kidney Replacement Therapy, Catheter Infection, Catheter Dysfunction, Catheter Related Bloodstream Infections
- Trial name
- DUKE (NCT06259266)
- Testing
- Anti-reflux valve for dialysis catheter
- Where
- France
- Sponsor
- University Hospital, Clermont-Ferrand
Anemia of Chronic Kidney Disease
Periodic Versus Continuous IV Iron Supplementation in HD Patients
The purpose of this study was to compare the efficacy of two regimens of intravenous iron sucrose [continuous (in every hemodialysis session) versus intermittent (every 1-4 weeks)] on the response of rHuEPO in the maintenance…
- Trial name
- NCT02787824
- Testing
- Iron Sucrose Supplement
- Where
- Greece
- Volunteers
- 27 people
- Sponsor
- Papageorgiou General Hospital
End Stage Renal Disease (ESRD)
AVF Stenosis by Electronic Stethoscope
The prevalence rate of hemodialysis in Taiwan is the highest in the world, and the number of new cases of hemodialysis and the death rate are gradually increasing every year.
- Trial name
- NCT07436559
- Testing
- Detection and Prediction of the stenosis of arteriovenous fistula in hemodialysis patients by an electronic stethoscope
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Thromboembolism, Hemodialysis
A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery
The purpose of this study is to better understand if either dalteparin or tinzaparin is a better drug to use in dialysis patients on blood thinners who are at high risk of developing blood clots and need surgery.
- Trial name
- NCT00260988
- Testing
- Fragmin (dalteparin), Innohep (tinzaparin)
- Where
- 2 sites in Canada
- Volunteers
- 29 people
- Sponsor
- Ottawa Hospital Research Institute
End Stage Renal Disease, Hemodialysis-Induced Symptom
Integrated Patient Care Intradialysis Programme in Hemodialysis Through a Virtual Health Platform
There is wide evidence regarding the weak points of end-stage Chronic kidney disease (CKD) patients in hemodialysis, and they include three intervention aspects: exercise, nutrition and psychological support.
- Conditions
- End Stage Renal Disease, Hemodialysis-Induced Symptom, Chronic Kidney Diseases
- Trial name
- GoodRENal (NCT04823286)
- Testing
- Virtual reality health platform during hemodialysis
- Where
- 8 sites in Belgium, Greece and 2 more
- Volunteers
- 41 people
- Sponsor
- Cardenal Herrera University
Kidney Failure, Chronic
Effects of Aerobic Training in End Stage Renal Disease Patients
The investigators raised the hypothesis that exercise training would be associated with improvement in exercise tolerance and VO2 kinetics in hemodialysis patients.
- Trial name
- NCT01234688
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Juiz de Fora
Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy
Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis
This study will evaluate the efficacy of SBR759 compared to sevelamer HCl in lowering serum phosphate levels in Chronic Kidney Disease patients on hemodialysis
- Trial name
- SBR759 (NCT00704483)
- Testing
- SBR759, Sevelamer HCl
- Where
- 66 sites in United States, Australia and 11 more
- Volunteers
- 321 people
- Sponsor
- Novartis Pharmaceuticals
Arteriovenous Fistula Maturation Failure in End-stage Renal Disease
Clinical and Mechanistic Research on Autogenous Arteriovenous Fistula in Hemodialysis Patients
This study aims to investigate the long-term clinical outcomes and molecular mechanisms of autogenous arteriovenous fistula (AVF) maturation failure in uremic patients.
- Trial name
- NCT07058441
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ai Peng
Renal Failure Chronic, Restless Legs Syndrome
Massage, Oxidative and Antioxidant Enzymes in Hemodialysis Patients With Restless Legs Syndrome(RLS)
This study; It will be done to evaluate the presence of oxidative stress and its effects on lipid peroxidation products and antioxidant parameters after massage application and the possible effects of the appropriate massage…
- Trial name
- RLS (NCT05787080)
- Testing
- Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baskent University
Chronic Kidney Disease on Hemodialysis
The Self-management Program on Hemodialysis Patients in Cambodia
Chronic kidney disease (CKD) is a growing global health issue, with increasing numbers of patients requiring kidney replacement therapy (KRT), particularly in low- and middle-income countries.
- Trial name
- NCT06871553
- Testing
- Self management education program
- Where
- Cambodia
- Volunteers
- 45 people
- Sponsor
- Hiroshima University
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