Clinical trials: Helminthiasis
Alveolar Echinococcosis
Alveolar Echinococcosis: Parasite Viability and Innovative Markers for the Follow-up of Patients Treated With Albendazole
Study design to define improved management of patients with hepatic alveolar echinococcosis treated with albendazole and especially make appropriate and timely decision of treatment withdrawal .
- Trial name
- EchinoVISTA (NCT02876146)
- Testing
- Benzimidazole
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Fascioliasis
Parasitological Evaluation of Fascioliasis in Clinically Suspected Patients .
WHO considers foodborne trematodes as neglected tropical diseases. Fascioliasis is the most widely distributed trematode reported from over 81 countries around the world it imposes its highest burden in developing countries
- Trial name
- NCT03869788
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Helminthiasis
Urine Albendazole Levels for Coverage Assessment
This project will develop and assess the feasibility and acceptability of a urine-based assay to monitor adherence to Mass Drug Administration (MDA) campaigns within Soil-transmitted helminthiasis (STH) control programs…
- Trial name
- NCT04041427
- Testing
- Albendazole Pill, High fat content diet, Moderate fat content die
- Where
- Argentina
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Salta
E. Granulosus Cystic Hydatid d
Epi Cystic Hydatid Disease Peru
This is a study developed by researchers from the Universidad Peruana Cayetano Heredia, the Universidad Mayor de San Marcos and other local and foreign institutions.
- Trial name
- NCT00138346
- Where
- 2 sites in Peru
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Taenia Solium Infection
Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa?
Taenia solium taeniosis/cysticercosis is a neglected zoonotic parasitic disease complex with significant economic and public health impacts, occurring primarily in developing countries.
- Trial name
- CYSTISTOP (NCT02612896)
- Testing
- Mass drug administration, praziquantel 10mg/kg, Health education
- Where
- Zambia
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Leprosy, Lymphatic Filariases
Integrating Mental Health Into Neglected Tropical Disease Care in Ghana
Background Neglected Tropical Diseases (NTDs) are a group of diseases that are more common among the poorest people in the poorest countries.
- Conditions
- Leprosy, Lymphatic Filariases, Buruli Ulcer, Onchocerciasis
- Trial name
- IMAGINE (NCT07248462)
- Testing
- WHO Essential Care package for mental health and NTDs
- Volunteers
- 200 people
- Sponsor
- Liverpool School of Tropical Medicine
Schistosomiasis Haematobia
Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection
Open labelled, non randomized study to evaluate the effects of Artemisinin based Combined Therapies(ACTs) on schistosomiasis since Praziquantel (PZQ) which is presently the drug of choice for treating Schistosomiasis (STS), is…
- Trial name
- SACT (NCT04264130)
- Testing
- Artesunate-Pyronaridine, Artemether-Lumefantrine, Artefenomel-Ferroquine
- Where
- Gabon
- Volunteers
- 54 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Schistosoma Mansoni
A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni
The purpose of this study is to determine the comparative efficacy of artesunate plus sulfamethoxypyrazine-pyrimethamine versus Praziquantel in the treatment of school children infected with S.mansoni in western Kenya.
- Trial name
- NCT01054651
- Testing
- Artesunate+Sulfamethoxypyrazine/pyrimethamine, Praziquantel
- Where
- Kenya
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kenya Medical Research Institute
HIV Infection, Nematode Infection
Study of Patients With Strongyloides Stercoralis Infection
This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease.
- Conditions
- HIV Infection, Nematode Infection, Strongyloidiasis
- Trial name
- NCT00001245
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Leishmaniasis, Cutaneous, Helminthiasis
Antihelminthic Therapy Combined With Antimony in the Treatment of Cutaneous Leishmaniasis
The purpose of this project is to investigate the efficacy of early, empiric anti-helminthic therapy combined with standard pentavalent antimony in the treatment of subjects co-infected with helminths and cutaneous leishmaniasis…
- Trial name
- NCT00469495
- Testing
- Anti-helminthic, meglumine antimony
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Urinary Schistosomiases
Circulating Cathodic Antigen Test Compared to Microscopy for Diagnosis of Urinary Schistosomiasis in Sohag
Schistosomiasis is a chronic infection endemic in 74 tropical and sub-tropical countries. Sub-Saharan Africa carries the highest burden (90%) of schistosomiasis which caused by both Schistosoma mansoni and Schistosoma…
- Trial name
- NCT05276414
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
Cystic Echincoccosis, Hydatid Disease
MR Assessment of Hepatic Hydatid Disease
Hydatid disease is a major healthcare problem worldwide caused by infection that commonly affects the liver. Treatments for hydatid disease depend on how advanced the disease is and if the infection is active or not.
- Trial name
- NCT03289884
- Testing
- MRI scan (not involving ionising radiation), Ultrasound scan (not involving ionising radiation), Ex vivo MRI scan of cyst fluid sample
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University College, London
Anaemia, Malaria
Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania
The proposed study has as the main objective to investigate the effect of schistosome and STH infections and the effect of an anthelminthic intervention on P.
- Conditions
- Anaemia, Malaria, Hepatosplenomegaly
- Trial name
- NCT00347113
- Testing
- Albendazole and praziquantel
- Where
- Tanzania
- Volunteers
- 620 people
- Sponsor
- DBL -Institute for Health Research and Development
Helminth Infections
A Study to Assess the Efficacy and Safety of Mebendazole for the Treatment of Helminth Infections in Pediatric Participants
The purpose of this study is to evaluate the efficacy and safety of mebendazole compared with placebo in pediatric participants with Helminth infections.
- Trial name
- NCT02034162
- Testing
- Mebendazole
- Where
- 3 sites in Ethiopia, Rwanda
- Volunteers
- 295 people
- Sponsor
- Janssen Research & Development, LLC
Trichuris Infection
Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita
The purpose of this clinical trial is to compare the efficacy and safety of emodepside with the standard treatment, albendazole, in adolescents (12 years and older) and adults infected with Trichuris incognita.
- Trial name
- EMOTI (NCT07258173)
- Testing
- Emodepside, Albendazole 400 mg
- Volunteers
- 100 people
- Sponsor
- Jennifer Keiser
Lymphatic Filariasis, Helminth Infection
Twice Yearly Treatment for the Control of LF
The Global Program for the Elimination of Lymphatic Filariasis (GPELF) has been in operation sing the year 2000, with the aim of eliminating the disease by the year 2020, following 5-6 rounds of effective annual Mass Drug…
- Trial name
- NCT03036059
- Testing
- 400 μg/kg Ivermectin + 400 mg Albendazole
- Where
- Ghana
- Volunteers
- 1,462 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Hookworm Infection
Hookworm Immune Regulation Project
The main objective of this study is to characterize the regulatory immune response induced by hookworm in an infected Vietnamese rural population from the periphery of HCM, evolution after infection treatment and during potential…
- Trial name
- HIRP-01 (NCT02262403)
- Testing
- Blood and feces sampling
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Brugmann University Hospital
Loiasis
Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis
Diethylcarbamazine citrate (DEC) treatment of Loa loa infection is complicated by the development of severe adverse reactions that are correlated with the number of circulating microfilariae in the blood.
- Trial name
- NCT01111305
- Testing
- Reslizumab, Diethylcarbamazine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Malaria, Filariasis
Medical Implications of Coinfection With Malaria and Filariasis Parasites
This study will examine the clinical, immunological and epidemiological effects of concurrent infections with P. falciparum and W. bancrofti or M.
- Trial name
- NCT00471666
- Where
- Mali
- Volunteers
- 1,039 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)