Clinical trials: Helicobacter Pylori Infections
Helicobacter Pylori Infection
The Prevalence of Family-unit Helicobacter Pylori Infection in Jiangsu
To assess Family-unit Helicobacter Pylori Infection rates and antimicrobial resistance rates in Jiangsu,China
- Trial name
- NCT05654857
- Testing
- PCR test in the stool
- Where
- 16 sites in China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Five Days Quadruple and Clarithromycin Containing Triple Therapy as Treatment for Helicobacter Pylori Eradication
The aim of this randomized trial is to compare the efficacy and tolerability of H. pylori eradication with a 5-day quadruple therapy versus a clarithromycin-containing triple therapy.
- Trial name
- NCT01306786
- Testing
- Quadruple therapy, Triple therapy
- Where
- Hong Kong
- Volunteers
- 800 people
- Sponsor
- The University of Hong Kong
Helicobacter Pylori Gastrointestinal Tract Infection
Comparison Efficacy of 14-day Triple Therapy: Clarithromycin vs. Levofloxacin on Eradication of H. Pylori
Comparison Efficacy of 14-day Triple Therapy between Clarithromycin and levofloxacin on the Eradication of Helicobacter Pylori in Syrian population
- Trial name
- NCT02693574
- Testing
- Clarithromycin, Levofloxacin
- Where
- Syria
- Volunteers
- 74 people
- Sponsor
- Damascus Hospital
H. Pylori Infection
Efficacy of Vonoprazan Based Dual and Triple Therapy for Patient With Helicobacter Pylori Infection
This study aims to assess Efficacy of vonoprazan based dual and triple therapy for naïve patient with Helicopacter Pylori infection in Sohag Government .
- Trial name
- NCT07045688
- Testing
- Efficacy of Vonoprazan based dual therapy for naive patient with Helicobacter Pylori infection, Efficacy of Vonoprazan based triple therapy for naive patient with Helicobacter Pylori infection, Efficacy of PPI based triple therapy for naive patient with Helicobacter Pylori infection
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
HELICOBACTER PYLORI INFECTIONS
Levofloxacin-Based Sequential Therapy Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
This randomized controlled trial aims to compare the efficacy and safety of levofloxacin-based sequential therapy versus bismuth-based quadruple therapy for eradication of Helicobacter pylori infection in adult patients.
- Trial name
- NCT07574983
- Testing
- Levofloxacin-Based Sequential Therapy, Bismuth-Based Quadruple Therapy
- Volunteers
- 90 people
- Sponsor
- University of Health Sciences Lahore
Helicobacter Pylori Infection
The Effect of Vitamin D Supplement as Adjuvant Therapy in Eradication of Helicobacter Pylori Infection
Helicobacter pylori (H. pylori) is one of the most common chronic infections worldwide. The mode of transmission of H. pylori is through the fecal-oral or oral-oral routes.
- Trial name
- NCT06964334
- Testing
- Lansoprazole, amoxicillin, clarithromycin
- Volunteers
- 70 people
- Sponsor
- Assiut University
H. Pylori Infection
Clinical Efficacy and Safety Assessment of Alsareen Capsule for the Management of H. Pylori Infection
Helicobacter pylori infection is a major cause of morbidity and mortality worldwide. More than 50% of the global population is estimated to be infected.
- Trial name
- NCT06304532
- Where
- Pakistan
- Volunteers
- 69 people
- Sponsor
- Hamdard University
Helicobacter Pylori Infection
High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection
This study is a multicentra, prospective study. The enrolled patients are HP positive. They are diagnosed as HP positive by rapid urease test and/or 13C urea breath test.
- Trial name
- NCT06561698
- Testing
- Vonoprazan, Amoxicillin, Bismuth Potassium Citrate
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
H.Pylori Infection
Efficacy and Safety of Rifasutenizol (TNP 2198), Rabeprazole and Amoxicillin in Participants With H. Pylori Infection
A multi-center, randomized, double-blind, bismuth-containing quadruple active comparator-controlled Phase 3 clinical study to evaluate the efficacy and safety of Rifasutenizol in combination with rabeprazole and amoxicillin in…
- Trial name
- NCT05857163
- Testing
- Rifasutenizol capsules, Rabeprazole sodium enteric-coated tablets, Amoxicillin Capsules
- Where
- China
- Volunteers
- 700 people
- Sponsor
- TenNor Therapeutics (Suzhou) Limited
Helicobacter Pylori 23S rRNA Clarithromycin Resistance Mutation, Helicobacter Pylori Infection
Empirical vs Tailored Therapy for H. Pylori Infection
We aimed to compare the efficacy of genotypic resistance-guided tailored therapy vs empirical therapy for eradication of Helicobacter pylori (H. pylori) infection in randomized controlled trials.
- Trial name
- NCT04006340
- Testing
- triple therapy, quadruple therapy, dual-priming oligonucleotide-based multiplex (DPO)-PCR test
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Hospital
Helicobacter Pylori Infection, Upper Endoscopy
Diagnosis of Helicobacter Pylori Based on Gastric Collecting Venules
Helicobacter pylori (Hp) is the major cause of gastritis and gastritis-associated diseases. Detection of a regular arrangement of collecting venules (RAC) pattern in the lesser gastric curvature correlates with negative Hp status…
- Conditions
- Helicobacter Pylori Infection, Upper Endoscopy, Regular Arrangement of Collecting Venules
- Trial name
- NCT04000243
- Testing
- Endoscopic diagnosis of Hp
- Where
- Spain
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Parkinson's Disease, Helicobacter Pylori Infection
Helicobacter Pylori Eradication Study in Parkinson's Disease
It has been hypothesized, based on epidemiological observations, that Helicobacter pylori (HP) infection may play a role in the pathogenesis of Parkinson's Disease (PD).
- Trial name
- NCT02108704
- Testing
- Helicobacter pylori eradication therapy
- Where
- Malaysia
- Volunteers
- 75 people
- Sponsor
- University of Malaya
Helicobacter Pylori Infection
Efficacy of Acetilcysteine in 'Rescue' Therapy for Helicobacter Pylori Infection. Pilot Study
H pylori gastric infection is one of the most prevalent infectious diseases worldwide. The discovery that most upper gastrointestinal diseases are related to H pylori infection and therefore can be treated with antibiotics is an…
- Trial name
- NCT00985608
- Testing
- Group A: NCA 600 mg+antibiotics, Group B: antibiotic treatment (control)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Helicobacter Pylori Infection
Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
The researchers collect treatment-naive H.pylori-positive patients from the outpatient clinic. The subjects were randomized to receive a 10-day or 14-day course of quadruple eradication therapy.
- Trial name
- NCT04901117
- Testing
- Amoxicillin, Clarithromycin, Tetracycline
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection, Eradication
Furazolidone Quadruple Regimen Eradicate H. Pylori Infection
Research protocol: Experimental group: First line solution (furazolidone regimen): esomeprazole magnesium 20 mg +colloidal bismuth pectin 200mg+ amoxicillin 1000 mg + furazolidone 100 mg, twice daily, for 14 days.
- Trial name
- NCT06823791
- Testing
- Furazolidone, Clarithromycin
- Where
- China
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Liaocheng People's Hospital
Helicobacter Infections
Specimen Collection Study for H. Pylori Testing
The objective of this study is to acquire human specimens from subjects undergoing routine endoscopy with gastric biopsy for the diagnosis of active H. pylori infection.
- Trial name
- NCT02970110
- Where
- 4 sites in United States
- Volunteers
- 98 people
- Sponsor
- Biomerica
HELICOBACTER PYLORI INFECTIONS
Optimizing H. Pylori Eradication Regimen Under Intensified Acid Suppression
Background: Helicobacter pylori (H. pylori) infection affects approximately 50% of the global population and is closely associated with chronic gastritis, peptic ulcer disease, and gastric cancer. Eradication of H.
- Trial name
- NCT07750938
- Testing
- Keverprazan Hydrochloride 20 mg TID, Minocycline 100 mg (10-Day Regimen), Keverprazan Hydrochloride 20 mg BID
- Volunteers
- 316 people
- Sponsor
- Qilu Hospital of Shandong University
Helicobacter Infections
Helicobacter Pylori and Dry Eye
This study will examine whether infection with Helicobacter pylori bacteria may cause inflammation of the eye's surface. Although most people who are infected with H.
- Trial name
- NCT00083291
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Helicobacter Pylori Infection, Gastric Ulcer
Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects
The primary objective is to obtain stool samples from pre-therapy subjects already undergoing evaluation for an H. pylori infection by upper esophagogastroduodenoscopy (EGD) and gastric biopsy.
- Conditions
- Helicobacter Pylori Infection, Gastric Ulcer, Nausea, Abdominal Pain
- Trial name
- NCT03060746
- Testing
- Newly Diagnosed
- Where
- 12 sites in United States, Italy
- Volunteers
- 277 people
- Sponsor
- DiaSorin Inc.
Vonoprazan, Helicobacter Pylori Infection
A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection
The treatment of helicobacter pylori is very important. The routine treatment is quadruple therapy. In recent years, double therapy has appeared and the curative effect is fair.
- Conditions
- Vonoprazan, Helicobacter Pylori Infection, Proton Pump Inhibitor
- Trial name
- VATH-1 (NCT05590286)
- Testing
- Vonoprazan Tablets, Amoxicillin Capsules, Esomeprazole
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou