Clinical trials: Heat Stress
Heat Stroke
Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke
The goal of this clinical trial is to test the cooling effect of cooling blanket in patients with heat stroke. The main questions it aims to answer are: the cooling rate of cooling blanket in patients with heat stroke the…
- Trial name
- NCT05923931
- Testing
- cooling blanket, non-cooling blanket
- Where
- 7 sites in China
- Volunteers
- 126 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Heat Stress, Heat Exposure
Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons
The global populace is at growing risk of heat-related illness due to climate change and accompanying increases in the intensity and regularity of extremely hot temperatures.
- Conditions
- Heat Stress, Heat Exposure, Temperature Change, Body, Temperature; Extreme, Exposure
- Trial name
- NCT05963529
- Testing
- Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heat Stress, Physiological Stress
Influence of Indoor Humidity on Physiological Strain in Older Adults During a Simulated Heat Wave
Laboratory-based studies show that exposure to high humidity can worsen the effects of heat stress in young and older adults by impeding sweat evaporation - the main mechanism by which the human body cools itself.
- Trial name
- NCT06842953
- Testing
- Simulated indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Gingival Enlargement
Temperature and Healing in Treatment of Gingival Enlargement
Aim: Gingival enlargement is a common clinical condition which requires surgical approaches to alleviating these enlargement areas.
- Trial name
- NCT04016064
- Testing
- Er:YAG LASER, Nd:YAG laser, elctrosurgery, conventional surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Hyperthermia
Rapid Cool: Heat Stroke Treatment
Hot climates such as in Phoenix, AZ commonly have individuals experiencing heat stroke, a life-threatening medical emergency. The dangerously high body temperature can result in death if not treated immediately with rapid body…
- Trial name
- NCT07743619
- Testing
- Recirculated water, Phoenix protocol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Neoplasms
Immunostimulating Interstitial Laser Thermotherapy in Solid Cancers
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT02690428
- Testing
- Immunostimulating Interstitial Laser Thermotherapy
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Clinical Laserthermia Systems AB
Bladder Cancer
A Study for Treatment of Superficial Bladder Cancer Using OGX-427
This is a single centre, open label, phase I dose escalation trial using a modified accelerated titration design. Patients with superficial bladder tumour (Ta or T1) or CIS and candidates for transurethral resection or muscle…
- Trial name
- NCT00959868
- Testing
- OGX-427
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Vancouver Coastal Health
Physiological Stress
Evaluating the Physiological Strain Induced by a BC Membrane Protective Garment Under Exercise-heat Stress Compared to a Protective Coverall
Israel ministry of defense is examining a new BC membrane protective garment of BLAUER company constructed with GORE CHEMPAK fabric for the border guard of the police forces.
- Trial name
- NCT02641535
- Testing
- exercise under hot and humid conditions protocol, BC membrane protective garment, NBC mask
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Rectal Cancer, Hyperthermia
The Effect of Electro-Hyperthermia in Preoperative Radiotherapy for Locally Advanced Rectal Cancer
Preoperative radiotherapy in locally advanced rectal cancer increases the possibility of complete resection and anal sphincter preservation.
- Trial name
- NCT02546596
- Testing
- Electro-hyperthermia
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei Hyperthermia Study Group
Cutaneous Warts, Human Papilloma Virus
Infrared Bioeffect System for the Treatment of Cutaneous Warts
Local hyperthermia at 44℃ can promote some alterations of immulogical indicators. The procedure is convenient in clinic, has high tolerance with less trauma and less pain.
- Trial name
- wart (NCT03734003)
- Testing
- liquid nitrogen, controllable infrared bioeffect system
- Where
- China
- Volunteers
- 88 people
- Sponsor
- First Hospital of China Medical University
Brain and Central Nervous System Tumors
GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma
Vaccines made from a person's tumor cells, such as gp96 heat shock protein-peptide complex, may help the body build an effective immune response to kill tumor cells.
- Trial name
- NCT00293423
- Testing
- HSPPC-96, Standard Surgical Resection
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- University of California, San Francisco
Hyperthermia
Impact of ICE on Exercise Performance in the Heat
The purpose of this study is to determine the effects of intermittent forearm cooling on exercise performance in the heat.
- Trial name
- NCT04596618
- Testing
- Forearm cooling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Solid Tumors, Non-small Cell Lung Carcinoma
A Study of DS-2248 in Participants With Advanced Solid Tumors
This phase 1 clinical trial is intended to understand the safety and tolerability of a new anticancer drug in subjects with advanced solid tumors.
- Trial name
- NCT01288430
- Testing
- DS-2248
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- Daiichi Sankyo
Heat
Heat Acclimation, Hand Cooling Efficacy, and Adaptation Maintenance.
This study had three aims: 1. To determine the impact of consecutive days of exercise on thermoregulation and cardiovascular strain. 2.
- Trial name
- NCT04053465
- Testing
- Heat acclimation, Exercise in a cool environment
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Locally Advanced Malignant Neoplasm
Registry Trial to Evaluate the Safety and Efficacy of Hyperthermia in Locally Advanced Cancers
Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sevagram, District Wardha, Maharashtra, India is located in a rural setup and caters to a very underprivileged patient population with limited resources to even pay for their…
- Trial name
- RESHMART (NCT05099809)
- Testing
- Hyperthermia
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Basal Cell Carcinoma, Squamous Cell Carcinoma Skin
Skin Cancer and Hyperthermia and Radiotherapy
The SAHARA trial assesses wether combining ultrahypofractionated accelerated radiotherapy (RT) with hyperthermia is as effective as standard hypofractionated high-dose radiation in treating non-melanoma skin cancer (NMSC).
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma Skin, Non-melanoma Skin Cancer
- Trial name
- SAHARA (NCT06384053)
- Testing
- Water-filtered infrared-A-hyperthermia (wIRA) hyperthermia combined, Radiotherapy (RT)
- Where
- 4 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Kantonsspital Winterthur KSW
Intraoperative Complications, Thermal Injury
Laparoscopic Cholecystectomy And Capacitive Coupling - Coag Versus Blend Mode Causing Thermal Injury at Port Site Skin
Monopolar radiofrequency energy is used to perform the laparoscopic cholecystectomy operation. The appearance of burns are common following laparoscopic cholecystectomy; particularly at the port site of the active electrode.
- Conditions
- Intraoperative Complications, Thermal Injury, Electrocoagulation
- Trial name
- NCT01664806
- Testing
- Covidien Triad monopolar generator
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Heat Stress
The Detection of Heat Stress by Assessing Individual Body Responses to Heat (Heat Strain) in Young and Healthy Non-athlete Participants
This study investigates and compares the within and in-between variances of the body responses to different heat stressors in a controlled lab-setting.
- Trial name
- HEATSTAR (NCT05622188)
- Testing
- Elevated ambient heat, Elevated relative humidity, Exertion
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Breast Cancer
Imaging HSP90 Inhibitor AUY922 on VEGF-89ZR-bevacizumab Positron Emission Tomography (PET)
Inhibition of Heat Shock Protein (HSP)90 is a new, promising treatment modality for cancer patients, particularly in the setting of resistance.
- Trial name
- NCT01081613
- Testing
- 89Zr-bevacizumab PET imaging
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- University Medical Center Groningen
Abdominal Hysterectomy for Benign Disease
Electrosurgical Bipolar Plasmakinetic Vessel Sealing During Abdominal Hysterectomy: A Randomized Controlled Trial
Objective: To compare the safety and efficacy of the use of bipolar plasmakinetic vessel sealing (Gyrus Pk) usage versus standard technique when performing total abdominal hysterectomy for benign disease.
- Trial name
- PKAHRCT (NCT00654849)
- Testing
- Plasmakinetic bipolar energy forceps, Abdominal Hysterectomy with traditional suture technique
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Hospital de Concentracion Norte de Petroleos