Clinical trials: Heart Failure Patients
Heart Failure, Congestive
Validation of a Mortality Prediction Model for Acutely Decompensated Heart Failure Patients
The purpose of this protocol is to determine if the 3 variable mortality prediction model established using data from a retrospective, multi-center patient registry (The ADHERE Acute Decompensated HEart FailuRE National Registry)…
- Trial name
- NCT00536367
- Testing
- No intervention - observational study only
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Brian Hiestand MD
Chronic Heart Failure, Edema
AquaPass Device in Treatment of CHF Patients
The AquaPass System is intended for enhancing fluid transfer through the skin, by increased sweat rate, in fluid overloaded patients.
- Conditions
- Chronic Heart Failure, Edema, CHF
- Trial name
- NCT05843201
- Testing
- The AquaPass System
- Where
- 2 sites in Israel
- Volunteers
- 18 people
- Sponsor
- AquaPass Medical Ltd.
Heart Failure
Validation of Electrical Cardiometry Versus Fick Method in Cardiac Output Measurement
The investigators would like to find out if AESCULON®, a new device that non-invasively and continuously measures cardiac output using electrical cardiometry, works as well as one existing method--Fick method in patients…
- Trial name
- NCT01568619
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF)
Clinical Trials for Elderly Patients With Multiple Disease
The CHROMED project focuses its investigation on the applicability of an integrated solution for a pathological condition which: a) is very prevalent in ageing patients and b) severely impairs quality of life: COPD with other…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Sleep Disordered Breathing (SDB)
- Trial name
- CHROMED (NCT01960907)
- Testing
- CHROMED monitoring system
- Where
- 6 sites in Estonia, Slovenia and 3 more
- Volunteers
- 312 people
- Sponsor
- Restech Srl
Atrial Fibrillation, Heart Failure
Effectiveness of Oral Anticoagulants in Elderly Patients With Non-Valvular Atrial Fibrillation and Heart Failure
Observational study of elderly individuals diagnosed with Non-Valvular Atrial Fibrillation and Heart Failure who are beginning oral blood thinners
- Trial name
- NCT03508271
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 60,000 people
- Sponsor
- Bristol-Myers Squibb
Coronary Artery Disease
Direct Endomyocardial Injection of Autologous Bone Marrow Cells to Treat Ischaemic Heart Failure
The purpose of this study is to determine whether direct endomyocardial injection of autologous bone marrow cells is effective for enhancement of neovascularisation in patients with ischaemic heart failure.
- Trial name
- END-HF (NCT01150175)
- Testing
- Endomyocardial Injection of Autologous Bone Marrow Cells, Endomyocardial Injection of Plasma
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Non-Ischemic Congestive Heart Failure
Safety and Efficacy of Adipose Derived Stem Cells for Non-Ischemic Congestive Heart Failure
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Heart Disease as assessed by a series of measurements…
- Trial name
- NCT01502501
- Testing
- Harvesting and Implantation of Adipose-Derived Stem Cells (ASCs)
- Where
- Mexico
- Sponsor
- Ageless Regenerative Institute
Heart Failure NYHA Class II
The Effect of Chan-Chuang Qigong on Fatigue, Exercise Capacity and Quality of Lifpatients With Heart Failure
This study aimed to investigate the impact of Chan-Chuang Qigong on fatigue, exercise capacity, quality of life, and heart function in heart failure patients.
- Trial name
- NCT06521281
- Testing
- Chan-Chuang qigong
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Chia-Lin Hsieh
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Symptomatic Congestive Heart Failure
Bilevel Positive Pressure Ventilation (BIPAP)in Patients With Sleep Disorders Breathing (SDB)and Congestive Heart Failure (CHF):Comparison of Two Diagnostic Methods
Successful treatment of pulmonary edema was first published in 1938 by A. L. Barach. Since then, this has been the accepted method of treating acute respiratory failure due to left heart failure and edema.
- Trial name
- NCT01501734
- Testing
- watch-pat
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Anthracyclines-Induced Cardiotoxicity, Cardiotoxicity
Dapagliflozin to Prevent Anthracycline-Induced Cardiotoxicity
Anthracyclines, such as doxorubicin, are effective anticancer agents but may cause dose-dependent cardiac injury, including early changes in left ventricular function and cardiac biomarkers.
- Trial name
- DAPA-AIC (NCT06888505)
- Testing
- Dapagliflozin (Forxiga)
- Where
- Iraq
- Volunteers
- 94 people
- Sponsor
- Hawler Medical University
Type 2 Diabetes Mellitus, Heart Failure
Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart Failure
This is a 24 week, multicenter, randomized, double-blind, parallel group, placebo-controlled study to investigate the effects of saxagliptin and sitagliptin on cardiac dimensions and function in patients with type 2 diabetes…
- Trial name
- MEASURE-HF (NCT02917031)
- Testing
- Saxagliptin, Sitagliptin
- Where
- 74 sites in United States, Bulgaria and 8 more
- Volunteers
- 348 people
- Sponsor
- AstraZeneca
Heart Failure, Acute Heart Failure
Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)
This is a randomized trial of protocolized diuretic therapy guided by urinary sodium compared to structured usual care in ED patients with AHF.
- Trial name
- ESCALATE (NCT04481919)
- Testing
- Protocolized diuretic therapy
- Where
- 2 sites in United States
- Volunteers
- 474 people
- Sponsor
- Vanderbilt University Medical Center
Heart Failure With Reduced Ejection Fraction
Effects of Preferential Left Ventricular Pacing on Ventriculoarterial Coupling and Clinical Course of Heart Failure
Randomized trial of adult patients to study the effects of preferential left ventricular pacing on ventriculoarterial coupling of both systemic and pulmonary circulation, indices of systolic and diastolic function of both…
- Trial name
- READAPT (NCT04420065)
- Testing
- Preferential left ventricular pacing, Biventricular pacing
- Where
- Greece
- Volunteers
- 220 people
- Sponsor
- National and Kapodistrian University of Athens
Heart Failure
GISSI-HF- Effects of n-3 PUFA and Rosuvastatin on Mortality-Morbidity of Patients With Symptomatic CHF
INTRODUCTION While pharmacological treatments specifically targeted to the cardio-circulatory system have been largely investigated, scanty controlled data are available concerning the role of dietary and metabolic approaches in…
- Trial name
- NCT00336336
- Testing
- n-3 PUFA, Rosuvastatin
- Where
- 337 sites in Italy, Switzerland
- Volunteers
- 6,975 people
- Sponsor
- Gruppo di Ricerca GISSI
Heart Failure, Heart Diseases
Effect of Targeted Interventions to Improve Value Based Health Care for Inpatient Cardiology Patients
The investigators hypothesize that a combined didactic and data feedback program presenting evidence based indications and in-hospital-charges for echocardiograms to inpatient cardiology team members will lead to increased health…
- Trial name
- NCT03173157
- Testing
- Value Feedback Email
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Vanderbilt University Medical Center
Heart Failure, Quality of Life
Focused Palliative Care Intervention in Advanced Heart Failure
This small pilot study will be assessing the the impact of a standardized, social-worker led, longitudinal palliative care intervention on alignment of patient and physician understanding of prognosis and goals of care.
- Trial name
- NCT02805712
- Testing
- Verbal Information and Discussion, Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure
Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure
This study is designed to understand the pharmacokinetics of different oral formulations of CK-1827452 being considered for future studies in patients with heart failure.
- Trial name
- NCT00941681
- Testing
- CK-1827452
- Where
- 3 sites in Georgia
- Volunteers
- 35 people
- Sponsor
- Cytokinetics
Congestive Heart Failure
Louisiana State University Health Care Sciences Division (LSU HSCD) Tele-Health Projects: Adult CHF Patient Population
The purpose of this research study is to see whether a tele-health intervention can improve health, functioning status, emotional status, quality of life, and patient satisfaction for patients with Congestive Heart Failure (CHF)…
- Trial name
- TeleHealth:CHF (NCT01148563)
- Testing
- Tele-health Monitoring
- Where
- 4 sites in United States
- Volunteers
- 136 people
- Sponsor
- Pennington Biomedical Research Center
Heart Failure, Systolic
Patient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart Failure
Real-world evidence of the clinical course of patient symptoms following initiation of sacubitril/valsartan via PROs with a patient-centered study design will provide important evidence of potentially beneficial outcomes…
- Trial name
- PROVIDE-HF (NCT03387163)
- Testing
- Sacubitril/Valsartan
- Where
- United States
- Volunteers
- 402 people
- Sponsor
- Novartis Pharmaceuticals