Clinical trials: Heart Disease Risk Factors
Preeclampsia, Hypertension
Cardiac and Immune Cell Function in Preeclampsia
Preeclampsia is a multi-system vascular disease which affects 2-5% of pregnancies. It is also a risk factor for the development of cardiovascular disease later in life and a number of functional and structural cardiac changes…
- Conditions
- Preeclampsia, Hypertension, Pregnancy Induced Hypertension, Pregnancy Related
- Trial name
- NCT04508582
- Testing
- Cardiovascular magnetic resonance, Echocardiography, Blood test
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Testicular Cancer, Seminoma
Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients
For many years, researchers and doctors have studied different kinds of treatments to improve the survival of men with testicular cancer.
- Conditions
- Testicular Cancer, Seminoma, Non-seminomatous
- Trial name
- NCT00705094
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- AHS Cancer Control Alberta
Angina Pectoris, Coronary Disease
Cardiac Rehabilitation for the Treatment of Refractory Angina
The purpose of this study is to determine whether cardiac rehabilitation is a successful treatment for refractory angina, in relation to improvements in cardiovascular risk factors, physical ability, symptomology, quality of life…
- Trial name
- NCT00411359
- Testing
- Cardiac rehabilitation
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- National Heart and Lung Institute
Alcohol Drinking, Drinking Behavior
Reducing Cardiovascular Risks: The Role of Alcohol Use
The purpose of this study is to learn whether avoiding alcohol can improve heart and blood vessel health in adults who regularly drink alcohol and have high blood pressure.
- Conditions
- Alcohol Drinking, Drinking Behavior, At-risk Drinking, Cardiovascular Risk Factor
- Trial name
- NCT07783061
- Testing
- Alcohol Abstinence, Control arm
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- The University of Texas at Arlington
Cardiovascular Risk Factor, Nicotine Dependence
Vaping High vs. Low Nicotine E-Liquid
This study will examine the effects of electronic cigarette e-liquid nicotine content in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=36).
- Trial name
- NCT04047836
- Testing
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Risk Factors, Hyperlipidemia
European Study of Cardiovascular Risk
The main objective of this study is to describe the management of patients with cardiovascular risk factors in primary prevention among different European countries.
- Conditions
- Cardiovascular Risk Factors, Hyperlipidemia, Hypertension, Diabetes
- Trial name
- EURIKA (NCT00882336)
- Where
- 775 sites in Austria, Belgium and 10 more
- Volunteers
- 7,200 people
- Sponsor
- AstraZeneca
Atherosclerosis, Cardiovascular Disease
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
The purpose of this study is to measure the change in bad cholesterol (LDL-C) with VERVE-102 compared to placebo in adults who have plaque buildup in their arteries or are at high risk of developing it.
- Conditions
- Atherosclerosis, Cardiovascular Disease, Hypercholesterolemia
- Trial name
- HEART-3 (NCT07839936)
- Testing
- VERVE-102
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Verve Therapeutics, Inc.
Long qt Syndrome, Torsade de Pointes
A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes
This is a registry to examine genetic and clinical predictors of torsade de pointes events.
- Trial name
- BA-TdP (NCT02439645)
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- Massachusetts General Hospital
Cardiovascular Health, Cardiovascular Risk Factors
The Effect of Women's Heart Health Awareness Program
The aim of this study is to examine the effect of a gender-specific heart health protection awareness program, incorporating video-supported reminder messages, on knowledge, attitudes, practices (KAP) regarding cardiovascular…
- Conditions
- Cardiovascular Health, Cardiovascular Risk Factors, Health Literacy
- Trial name
- NCT07502911
- Testing
- Heart Health Awareness Program
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Depression, Anxiety
Postoperative Anxiety and Depression Among Chinese Elderly Patients
The goal of this observational study is to learn about the prevalence of postoperative anxiety and depression symptoms and identify the related risk factors in elderly patients aged 65 and older who undergo non-cardiac surgery in…
- Trial name
- NCT07532122
- Where
- China
- Volunteers
- 7,568 people
- Sponsor
- Chinese PLA General Hospital
Smoking Status, Genetic Risk Factors
Effect of Smoking Status and Genetic Risk Factors on Restenosis and Efficacy of Clopidogrel After de Novo Percutaneous Coronary Intervention
Restenosis occurs for many different reasons. Over the years, many predictive clinical, biological, genetic, epigenetic, lesion-related, and procedural risk factors for restenosis have been identified.
- Conditions
- Smoking Status, Genetic Risk Factors, Restenosis, Clopidogrel
- Trial name
- NCT03613337
- Testing
- clinical restenosis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Cui Yimin
Acute Kidney Injury, Cardiogenic Shock
Acute Kidney Injury in Adult Patients Supported by VA-ECMO
Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane…
- Trial name
- AKI-ECMO (NCT04082312)
- Testing
- No intervention
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Cardiovascular Risk Factors, Clinical Practice Guideline
Development, Implementation and Evaluation of the Impact of a Guideline in Clinical Practise for Cardiovascular Risk
The aim of this study is to evaluate the impact of a clinical guideline in cardiovascular risk, with a local adaptation model of the existing guidelines in clinical practise at present, of each of the different cardiovascular…
- Conditions
- Cardiovascular Risk Factors, Clinical Practice Guideline, Implementation Strategies, Primary Care
- Trial name
- NCT01270022
- Testing
- Implementation, dissemination
- Where
- Spain
- Sponsor
- Gerencia De Atencion Primaria Area 2 De Madrid
Cardiovascular Diseases, Cardiovascular Risk Factor
Local Antioxidant Therapy Vasoconstriction Effects in Different Races
Cardiovascular disease (CVD) afflicts nearly one-third of the adult population with all races and ethnicities represented in CVD prevalence.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
- Trial name
- NCT03684213
- Testing
- Control (Norepinephrine), Norepinephrine + Ascorbic Acid, Norepinephrine + L-NAME
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Heart Attack, Stroke
CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?
This project aims to reduce disparities in cardiovascular disease (CVD) risk factor control and in rates of heart attacks and strokes among the low-income, racially / ethnically diverse Americans who receive primary care at…
- Conditions
- Heart Attack, Stroke, Cardiovascular Diseases
- Trial name
- CV_WIZARD (NCT03001713)
- Testing
- CV WIZARD
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cardiovascular Diseases, Heart Disease Risk Factors
Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring
This pilot study uses a state-of-the-science combination of remote behavioral monitoring, real-time experience sampling, in-lab physiological assessments, and extraction of neighborhood-level characteristics to (1) Examine the…
- Trial name
- BLOOM (NCT06150989)
- Testing
- Observational Group
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Coronary Artery Disease, Microcirculation Resistance
COronoary Microcirculation Analysis NETwork
COMA.NET (Coronary Microcirculation Analysis Network) is a prospective, randomized, open-label, parallel-group clinical trial designed to determine whether endotype-guided pharmacotherapy is superior to standard care in improving…
- Conditions
- Coronary Artery Disease, Microcirculation Resistance, Microcirculation; Biomarkers; Myocardial Ischemia, Microcirculatory Dysfunction
- Trial name
- COMA-NET (NCT07498231)
- Testing
- Coronary microvascular function assessment
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Medical University of Bialystok
Coronary Artery Disease, Risk Factor
Asan Medical Center CCTA Registry
A total of 9269 adults who received CCTA scans for coronary disease evaluation during a general medical checkup at the Health Screening and Promotion Center in Asan Medical Center, Seoul, Korea between January 2007 and December…
- Conditions
- Coronary Artery Disease, Risk Factor, Computed Tomography
- Trial name
- NCT06036901
- Testing
- Coronary CT
- Volunteers
- 6,343 people, healthy volunteers welcome
- Sponsor
- CardioVascular Research Foundation, Korea
High Blood Pressure, Hypercholesterolemia
Cardiovascular Risk Factors And Intensive Dietary Counselling
The Intensive Dietary Counselling (IDC) intervention is a prevention and health promotion activity. It is being implemented by the Andalusian Health Service to reinforce basic intervention advice on healthy diet and exercise.
- Conditions
- High Blood Pressure, Hypercholesterolemia, Tobacco Smoking
- Trial name
- NCT02173600
- Testing
- Group-level Intensive dietary Counselling, Individual-level Intensive Dietary Counselling
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Andalusian Regional Ministry of Health
Heart Failure, Cardiovascular Risk Factor
Feasibility of the Implementation of Tools for Heart Failure Risk Prediction
The purpose of this study is to gather information to develop a heart failure screening and prevention program.
- Trial name
- FIT-HF (NCT04684264)
- Testing
- Heart Failure Prevention Clinic
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
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