Clinical trials: Healthy Subjects
Healthy
Drug-Drug Interaction Study to Evaluate the Effect of DWC202511 or DWC202512 With DWP16001 in Healthy Adults
Drug-Drug Interaction Study to Evaluate the Effect of DWC202511 or DWC202512 With DWP16001 in Healthy Adults
- Trial name
- NCT07213310
- Testing
- DWP16001, DWC202511, DWC202512
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy
Bioavailability of BIBR 953 ZW Under Influence of Food in Healthy Subjects
Study to investigate the relative bioavailability of BIBR 953 ZW after administration of a 150 mg BIBR 1048 HPMC (hydroxypropylmethylcellulose) capsule versus BIBR 953 ZW after administration of a 150 mg BIBR 1048 gelatine…
- Trial name
- NCT02170597
- Testing
- BIBR 1048 MS HPMC capsule, BIBR 1048 MS gelatine capsule
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Prehypertension
Effect of Cardio Mato (Grade A Lyc-O-Mato, a Tomato Extracted Lycopene) on Blood Pressure
The hypothesis of the study is that supplementation with Cardio Mato (a Tomato Extracted Lycopene)for 12 weeks will decrease the blood pressure of subjects with prehypertension compared to Placebo.
- Trial name
- NCT01667510
- Testing
- Cardio Mato
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Avian Influenza
Safety and Pharmacokinetics Study of FBF001
The purpose of this study is to assess the clinical and laboratory safety and to determine the pharmacokinetic profile of FBF001.
- Trial name
- NCT02295813
- Testing
- FBF001
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fab'entech
Healthy
Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6
CYP2D6 is characterized by a huge variability in the general population, mainly because of genetic polymorphism and drug-drug interactions (DDIs). CYP2D6 genotype is known to have an impact on the extent of DDIs.
- Trial name
- NCT03054220
- Testing
- Dextromethorphan 5 MG, Tramadol 10 mg, Duloxetine 60mg
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Regional Anesthesia Morbidity, Pain, Acute
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
Regional anesthesia decreases postoperative pain scores and opioid consumption, and may prevent chronic pain after surgery in patients undergoing surgery.
- Conditions
- Regional Anesthesia Morbidity, Pain, Acute, Healthy
- Trial name
- NCT06005480
- Testing
- Mepivacaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Mountain Sickness
Safety Evaluation of Aminophylline and Methazolamide
This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
- Trial name
- NCT01587027
- Testing
- Aminophylline, Methazolamide, Aminophylline and Methazolamide
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System
Healthy
PET Study of Repeated ASN51 in Healthy Volunteers
This is a phase 1, open-label, dose escalation, positron emission tomography (PET) study to investigate the brain occupancy of O-GlcNAcase, and the pharmacodynamics (PD) response in peripheral blood mononuclear cells (PBMCs)…
- Trial name
- NCT05725005
- Testing
- ASN51
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Asceneuron S.A.
Clinical Pharmacology, Healthy Volunteer Study
A Phase 1 QT Study in Healthy Male Subjects
This is a single-center, randomized, double-blind crossover study with four treatments, four periods and four sequences to investigate the effects of orally administered pomalidomide on QT interval.
- Trial name
- QT/QTc (NCT01986894)
- Testing
- Pomalidomide, Moxifloxacin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Inhaled XQ-001 in Healthy Subjects
The primary study objective is to evaluate the safety and tolerability of XQ-001 for inhalation after single and multiple nebulized inhalation administration in healthy Chinese adult subjects.
- Trial name
- NCT06918366
- Testing
- Part A - single rising dose 1, Part A - single rising dose 2, Part A - single rising dose 3
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Brilliant Inspiration Biotherapeutics
Healthy
Study to Evaluate the Immunogenicity and Safety of Hantavax in Healthy Adult
This study was aimed to evaluate the Immunogenicity and Safety response by vaccinating Hantavax in Healthy Adult.
- Trial name
- NCT02553837
- Testing
- Hantavax injection
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Green Cross Corporation
Hypertension
Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-339 in Healthy Volunteers
This study is a randomized, open-label, single dose, crossover study to evaluate the pharmacokinetics and safety of CKD-339 in healthy volunteers.
- Trial name
- NCT07748702
- Testing
- CKD-339, D311, D107
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Acute Pain
First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy Volunteers
Acute pain relief in emergency setting is still a public health priority. Pain is the primary reason for emergency room use, but the situation of "oligo-analgesia" persists in all countries.
- Trial name
- AEROMORPH1 (NCT01975753)
- Testing
- Morphine, Fentanyl
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Healthy
Implant Pharmacokinetic and Pharmacodynamic Study
This is a single center, pharmacokinetic and pharmacodynamic study in healthy volunteers. Twenty four subjects will be enrolled in the study and will be assigned to receive either a 16 mg afamelanotide bioresorbable implant from…
- Trial name
- NCT03634137
- Testing
- Afamelanotide Group 1, Afamelanotide Group 2
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clinuvel Pharmaceuticals Limited
Addiction
A Study to Assess 18-Methoxycoronaridine (18-MC HCl) in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of a single day dosing and a separate multiple day dosing of 18-MC HCl administered orally, each part of the study having a different set of healthy…
- Trial name
- NCT04292197
- Testing
- 18-MC Compound
- Where
- Australia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Definium Therapeutics US, Inc.
Neuromuscular Performance, Balance and Function
Immediate and Delayed Effects of Kinesio Taping on the Neuromuscular Performance
The purpose of this study is analyze the immediate and late effects of the application of KT in neuromuscular performance of the quadriceps in postural balance and function of the lower limb of healthy subjects.
- Trial name
- IDEKTNP (NCT02431910)
- Testing
- Functional elastic tape
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Amyotrophic Lateral Sclerosis (ALS)
A First in Human Study of ORT247 in Healthy Volunteers
This is a single center, double-blinded, randomized, placebo controlled single ascending dose clinical study, with the primary purpose of evaluating the safety, tolerability, pharmacokinetics (PK), and immunohistochemistry of…
- Trial name
- NCT06769620
- Testing
- ORT247
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Orthogonal Neuroscience Inc.
Parkinson Disease
Study To Assess the Safety and Tolerability of PBF-509 in Male Healthy Volunteers
No clinical trials with PBF-509 in humans have been performed to date. Only preclinical studies have been done to assess the pharmacology and pharmacokinetics, the safety and the toxicological profile of the PBF-509.
- Trial name
- NCT01691924
- Testing
- PBF-509
- Where
- 2 sites in Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Hypertension
Bioequivalence Study in Healthy Subjects
This study is designed as a Phase-I, 2-period, cross-over, randomised, open-label, single centre study to determine bioequivalence of a single 32 mg dose of the proposed commercial oral suspension of candesartan cilexetil (1…
- Trial name
- NCT00844324
- Testing
- Candesartan cilexetil
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Adult Subjects
A Food Effect Study of SHR1459 on Healthy Chinese Adult Subjects
The primary objective of the study is to evaluate the effect of high-fat diet on pharmacokinetics of healthy Chinese adult subjects after oral administration of SHR1459 tablets.
- Trial name
- NCT04291846
- Testing
- SHR1459 fasted in P1, high-fat diet in P2, SHR1459 high-fat diet in P1, fasted in P2
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
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