Clinical trials: Healthy Related
Healthy, Chronic Stable Illness
Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19
The primary objectives are: To assess the occurrence of adverse events of special interest (AESIs) in participants treated with repeated subcutaneous (SC) doses of REGN10933+REGN10987 compared to placebo To assess the…
- Trial name
- NCT04519437
- Testing
- REGN10933+REGN10987
- Where
- 7 sites in United States
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Substance Dependence
A Study To Investigate The Safety, Tolerability And Blood Levels Of GSK598809
GSK598809 is being developed to facilitate overcoming an addiction to nicotine and to help people stop smoking. This study will investigate if GSK598809 is safe and tolerated in people who smoke and will also look at blood levels…
- Trial name
- NCT00437840
- Testing
- GSK598809
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tobacco Dependence
A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining
Participants will be smokers who want to quit, and have visible nicotine stains on their teeth. They will be given toothpaste and a toothbrush to use during the study, and will have an equal chance of being assigned to use either…
- Trial name
- NCT01440985
- Testing
- Nicotine
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- McNeil AB
Relapse Remitting Multiple Sclerosis
Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.
This study evaluates the impact of ofatumumab in Relapsing Remitting Multiple Sclerosis (RRMS) participants that are very early in the course of their disease using clinical and magnetic resonance imaging (MRI) outcomes.
- Trial name
- AGNOS (NCT05084638)
- Testing
- Ofatumumab
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Post Traumatic Stress Disorder
A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects
This is an open-label, single, ascending dose study evaluating the PK and safety of methylone in healthy subjects.
- Trial name
- NCT06303648
- Testing
- Methylone
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcend Therapeutics
Cognitive Wellness, Healthy Aging
MEVA Cognitive Wellness Platform Study for Adults
The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.
- Conditions
- Cognitive Wellness, Healthy Aging, Age-Related Cognitive Change, Aging
- Trial name
- MEVA (NCT07595250)
- Testing
- MEVA Cognitive Wellness Platform
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mentage LLC
Healthy
Acute Berry Intake on Metabolic Control and Cognitive Function
The objectives of this study are: 1. Evaluate the effects of acute dietary raspberry intake on metabolic-associated impairments in cognitive and psychomotor function in overweight/obese adults (55-70y) following a meal challenge…
- Trial name
- RRB3 (NCT03879213)
- Testing
- Active breakfast, Control breakfast
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Obesity
A Study to Characterize Event Related Potential Markers of Attentional Bias Towards Words and Images of Food
GSK is planning to undertake two anti-obesity drug studies in the area of obesity. In addition to assessment by questionnaires, it would be of significant value to incorporate an objective non-interventional measure of cognitive…
- Trial name
- NCT01366508
- Testing
- High calorie lunch, Breakfast
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Macular Degeneration, Age-related Macular Degeneration
A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.
This is a two-part study to evaluate the safety, tolerability and pharmacokinetics of single (Part A) and repeat (Part B) eye drop doses of pazopanib in healthy adult and elderly subjects.
- Trial name
- NCT00463320
- Testing
- Pazopanib eye drops and Allergen Refresh Plus eye drops
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fatty Liver
Study to Assess the Relationship Between Daily Dosing of NRPT and Changes in Liver Fat in Healthy Volunteers
The purpose of this study is to determine if there is a relationship between daily consumption of NRPT, over a six-month (26-week) period, and changes in liver fat accumulation, compared to placebo and change from Baseline in…
- Trial name
- NCT03513523
- Testing
- Group 1 NRPT, Group 2 NRPT
- Where
- 9 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Elysium Health
Tobacco Dependence
Pharmacokinetics With a New Oral Nicotine Replacement Product and Nicorette® Gum
Single-dose pharmacokinetics with a new oral nicotine replacement product and Nicorette® gum.
- Trial name
- NCT01152736
- Testing
- Nicotine
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- McNeil AB
Healthy Subjects, Overactive Bladder
An Exploratory Study to Investigate Bladder Contractions in the Storage Phase and Related Bladder Sensations in Healthy Females and Females With Overactive Bladder (OAB) Using High Resolution and Conventional Urodynamics
This study aims to identify differences in bladder contractions during the storage phase (non voiding activities) between OAB subjects and healthy subjects, using high resolution urodynamics.
- Trial name
- NCT01540786
- Testing
- High resolution urodynamic assessment, Conventional urodynamic assessment
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe Ltd.
Tobacco Dependence
Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum
Bioequivalence between oral nicotine replacement products and Nicorette® gum.
- Trial name
- NCT01113424
- Testing
- Nicotine, Nicorette® (Nicotine Gum)
- Where
- Sweden
- Volunteers
- 88 people
- Sponsor
- McNeil AB