Clinical trials: Healthy Overweight/Obese
Weight Gain, Healthy Subjects
Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Background: Rates of obesity have increased dramatically in recent decades, and researchers are investigating how changes in diets and physical activity have contributed to this increase.
- Conditions
- Weight Gain, Healthy Subjects, Obesity, Women
- Trial name
- NCT01251887
- Testing
- Linoleic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Pediatric Obesity, Pediatric Overweight
Comparing Outcomes Among Children With Obesity in a Community Healthy Lifestyle Program
This study aims to evaluate the outcomes of an existing clinical program that teaches families of children with overweight and obesity healthy lifestyle. The design will be unblinded, randomized, waitlist control.
- Conditions
- Pediatric Obesity, Pediatric Overweight, Overweight , Obesity
- Trial name
- 73357 (NCT07342855)
- Testing
- Get Up & Go Healthy Lifestyle Program
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
A Drug-Drug Interaction Study to Examine the Impact of Itraconazole and Cyclosporine on PF-07081532 Pharmacokinetics in Overweight or Obese Adults
This is a Phase 1, open-label, fixed-sequence, 3-period study to evaluate the effect of multiple doses of itraconazole and a single dose of cyclosporine on the single-dose PK of PF-07081532 in otherwise healthy, overweight or…
- Trial name
- NCT05745701
- Testing
- PF-07081532, Cyclosporine, Itraconazole
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity
Application of Dietary Guidelines for the Brazilian Population by Teleconsultation in Obesity in Primary Care
Obesity is a chronic disease that is highly prevalent in Brazil. It is associated with diabetes and hypertension. Obesity may decrease quality of life.
- Trial name
- NCT05171907
- Testing
- Teleobesity
- Where
- Brazil
- Volunteers
- 578 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obesity, Normal Physiology
Energy Expenditure Responses to Different Temperatures
Background: The way that the body burns calories is known as energy expenditure. Some studies show that when we are cold, we burn more calories to keep our bodies warm.
- Trial name
- NCT01568671
- Testing
- Room temperatures
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Overweight Obese
Gelesis200 Safety and Tolerability Study and Effects on Glycemic and Appetite Parameters
The purpose of this study is to determine the safety and tolerability of Gelesis200.
- Trial name
- STAGE (NCT02652962)
- Testing
- Gelesis200
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gelesis, Inc.
Overweight, Obesity
A Study to Test Whether BI 456906 (Survodutide) Influences the Amount of Bupropion, Caffeine and Midazolam in the Blood in People With Overweight or Obesity
This study is open to adults with overweight or obesity who are otherwise healthy. People can join the study if they have a body mass index of 27 to 39.9 kg/m2 and a body weight over 70 kg.
- Trial name
- NCT06564441
- Testing
- Survodutide, Bupropion, Caffeine
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Overweight or Obesity
A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers
This Phase I, active-controlled, randomised trial will be conducted in 2 parts. Part I aims to confirm the PD equivalence of EMP22 and Xenical® based on percent fecal fat excretion at steady state.
- Trial name
- NCT06013163
- Testing
- Xenical® vs EMP 22, EMP 22 vs Xenical®, EMP 16 vs Xenical®
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Empros Pharma AB
Hypertension (HTN), Diabetes (DM)
Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health (Healthy Heart - CKM)
The investigators are proposing a new team-based shared decision-making (SDM) program. The goal of this study is to see whether this program is practical and whether it may help adults with cardiometabolic risk factors and…
- Conditions
- Hypertension (HTN), Diabetes (DM), Hyperlipidaemia, Kidney Disease
- Trial name
- SDM in CKM (NCT07662616)
- Testing
- Team-based shared decision-making
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Healthy, Obesity & Overweight
Growth Hormone Resistance of Beta-cells
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with impaired fasting glucose or impaired…
- Conditions
- Healthy, Obesity & Overweight, Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (Prediabetes)
- Trial name
- GHRB-C (NCT07581860)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Child Obesity
YES! We Can PLAY: A Physical Activity and Nutrition After-School Program for Middle School Students
YES! We can PLAY: A Physical Activity and Nutrition After-School Program for Middle School Students, is a collaborative partnership between the University of Alabama at Birmingham and the Birmingham City Schools District to…
- Trial name
- NCT04132869
- Testing
- Sports Readiness Intervention
- Where
- 2 sites in United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Overweight and Obesity
The Feasibility and Preliminary Efficacy of the Mindful-Healthy Family Intervention With Rural Families
This two-group RCT, the Mindful-Healthy Family project, will test the feasibility and preliminary efficacy of a mindfulness-based Motivational Interviewing (MM-based-MI) intervention with rural families within Michigan.
- Trial name
- MHFproject (NCT05324969)
- Testing
- MM-based MI, healthy education
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Healthy, Type 2 Diabetes
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
- Conditions
- Healthy, Type 2 Diabetes, Obesity
- Trial name
- NCT05264727
- Testing
- Dextrose, Clinisol 15%
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
Our Year of Healthy Living (Formative Research & Intervention)
The purpose of this study is to evaluate the effect of a 7-month social marketing program - Healthy Me, Healthy We (previously called Our Year of Healthy Living) - in improving preschool children's (3-4 years) diet and physical…
- Trial name
- NCT02330354
- Testing
- Healthy Me, Healthy We
- Where
- United States
- Volunteers
- 2,293 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Weight Gain, Diet, Healthy
Implementation of a Mediterranean Diet Program for Overweight or Obese Pregnant Women in a Low-resource Clinical Setting
The purpose of this Pilot randomized clinical Trial is to compare two healthy diet styles during pregnancy. Patients between 8 and 16 weeks of gestation who agree to participate will be randomly assigned (like flipping a coin) to…
- Trial name
- MedDiet (NCT05868954)
- Testing
- MedDiet Program, ACOG-based Dietary Program
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy, Obesity
A Study of LY3971297 in Healthy Participants
The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP).
- Conditions
- Healthy, Obesity, Hypertension
- Trial name
- NCT06148272
- Testing
- LY3971297, LY3971297 IV
- Where
- 7 sites in United States, Japan and 1 more
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes Mellitus, Obesity
Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance
Agonistic activation of fat metabolite responsive G-protein-coupled receptors (GPCR) has been linked to improved glucose metabolism through increased glucose-stimulated-insulin-secreting (GSIS) and incretin release, improved…
- Trial name
- NCT03774095
- Testing
- Hydrolyzed pine nut oil, Hydrolyzed pine nut oil and olive oil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karina Vejrum Sørensen
Obesity, Infertility, Female
Internet-based Intervention to Promote a Healthy Lifestyle on the Reproductive Parameters of Overweight and Obese Women
Obesity and overweight are among the problems that produce infertility. The combination of diet and exercise to achieve weight loss are currently considered an effective intervention for the improvement of reproductive parameters…
- Trial name
- HLRP-RCT (NCT04275869)
- Testing
- Healthy Lifestyle
- Where
- Spain
- Sponsor
- Cardenal Herrera University
Obesity
Choosing Healthy Options in College Environments and Settings
Examine the effectiveness of a weight gain prevention intervention to positively affect body mass index in 2-year college students
- Trial name
- CHOICES (NCT01134783)
- Testing
- CHOICES Intervention
- Where
- 3 sites in United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- University of Minnesota