Clinical trials: Healthy Normal Weight
Diabetes, Fatty Liver
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Background: Vitamin E is an antioxidant that reduces the damaging effects of oxygen in the body. Most American men (90%) and women (96%) do not get enough vitamin E from their diets; however, the amount of vitamin E needed by the…
- Conditions
- Diabetes, Fatty Liver, Obesity, Healthy Volunteers
- Trial name
- NCT00862433
- Testing
- Alpha tocopherol, Vitamin E, Vitamin C
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy, Normal Weight
Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts
The researchers will investigate blood and fecal responses in qualified study participants after eating walnuts for 4 weeks compared to not eating walnuts for 4 weeks.
- Conditions
- Healthy, Normal Weight, Overweight, Obese
- Trial name
- NCT04307628
- Testing
- Walnut, Nut-Free
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Normal Weight
Meal Texture and Satiety
The aim of the present study is to compare the nutritional compensation between iso-caloric meals of various textures (liquid vs solid) in health young adults.
- Trial name
- FEED (NCT04041752)
- Testing
- SOLID, LIQUID_P, LIQUID_L
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy, Glucose Metabolism Disorders
Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals
Asians tend to develop type 2 diabetes (T2D) at lower body mass index (BMI) levels and younger ages compared to other populations.
- Conditions
- Healthy, Glucose Metabolism Disorders, Obesity, Visceral, Obesity; Endocrine
- Trial name
- MONW (NCT06802341)
- Testing
- Normal protein diet, Animal protein diet, Plant based diet
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Healthy, Obese
Exercise Regulation of Human Adipose Tissue
The purpose of this study is to determine whether exercise training leads to changes in the white adipose tissue that are beneficial to the body's regulation of sugar and body weight.
- Conditions
- Healthy, Obese, Diabetes Mellitus, Type 2
- Trial name
- NCT03133156
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Healthy
Effect of Garlic on Inflammatory Mediators
This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.
- Trial name
- NCT00275405
- Testing
- Garlic Oil Macerate
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Body Weight, Non-restrained Eaters
Appetite Suppression Trial With Polydextrose
Overweight and obesity are a global epidemic, which causes a rapid increase in the frequency of diabetes and cardiovascular diseases.
- Trial name
- NCT02064205
- Testing
- 12.5 g polydextrose, glucose syrup
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W.J. Pasman
Healthy, Obesity
Mitochondrial Function in Circulating Cells and Muscle Tissue
The main goal of this project is to determine whether mitochondrial function in circulating cells is related to that measured in the muscle fibers of the same subjects.
- Conditions
- Healthy, Obesity, Insulin Sensitivity, Women
- Trial name
- MitoWomen (NCT02700698)
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Immune System Tolerance, Depression
ESAN II - Energy Sensing in Depression
The purpose of this study is to assess the effects of polyphenols from natural aronia juice on the immune system. Therefore, the study aims to distinguish the effects of natural juices that are rich in phytonutrients such as…
- Conditions
- Immune System Tolerance, Depression, Obesity, Microbial Colonization
- Trial name
- NCT05432362
- Testing
- Aronia Juice
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Healthy Volunteers
Influence of Intragastric Fatty Acid Infusion on Behavioral Responses to Positive Emotion Induction in Healthy Subjects
The purpose of this study is to test whether intragastrically infused fatty acid will interact with positive emotion induction and if this effect is mediated by gut hormones.
- Trial name
- NCT02982616
- Testing
- Dodecanoic acid, Positive emotion, saline
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy, Normal Weight
Olive Oil Polyphenols and Cardiovascular Health Biomarkers
The purpose of this research is to investigate whether consuming two different kinds of olive oil will change risk factors related to cardiovascular disease, including levels of good and bad cholesterol, levels of inflammation…
- Conditions
- Healthy, Normal Weight, Overweight, Obese
- Trial name
- NCT04149288
- Testing
- High-polyphenol olive oil, Low-polyphenol olive oil
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Breast Cancer, Overweight and Obesity
Acceptance and Usability of an App Promoting Healthy Behaviours Amongst Young Women at Increased Risk of Breast Cancer
It is estimated that around 20% of breast cancers (BC) in the UK are preventable through adherence to appropriate health behaviours, i.e., healthy diet, physical activity, limited alcohol, not smoking, and that women at increased…
- Conditions
- Breast Cancer, Overweight and Obesity, Diet, Healthy, Weight Gain
- Trial name
- NCT05460650
- Testing
- App Promoting Healthy Behaviours
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Obesity, Insulin Resistance
Small Extracellular Vesicles and Insulin Action
The goals of this research study are to: 1) understand why some people with obesity are protected from developing conditions such as type 2 diabetes and cardiovascular disease while others are more likely to develop…
- Conditions
- Obesity, Insulin Resistance, Metabolically Healthy Obesity, Obesity, Metabolically Benign
- Trial name
- SEV (NCT05933707)
- Testing
- People with Metabolically Unhealthy Obesity - Low Calorie Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy, Obesity
A Study of Adipose Tissue in Adaptive Responses to Exercise
The purpose of this research is to determine how exercise affects fat (adipose) tissue and how changes to adipose tissue that occur during and after exercise might improve health in aging and obesity.
- Trial name
- NCT06053125
- Testing
- Adipose Tissue Biopsy, Exercise
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Body Weight, Healthy
Whey Protein Supplementation and Resistance Training in Older Women With Sarcopenic Obesity.
The main purpose of the present study was to investigate the effects of whey protein following resistance training on body composition, muscular strength, functional capacity, and plasma-metabolism biomarkers in older women with…
- Trial name
- NCT03752359
- Testing
- whey protein
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Obesity
Exenatide and Brown Adipose Tissue
The obesity epidemic has led to a enormous increase in the prevalence of type 2 diabetes mellitus (T2D), dyslipidemia and cardiovascular events.
- Trial name
- exe01 (NCT03002675)
- Testing
- Bydureon
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ingrid Jazet
Obesity, Type 2 Diabetes
Cold Stress Stimulate the Browing of Subcutaneous White Adipose in Healthy Adults
Adipose tissues, which include white adipose tissue (WAT) and brown adipose tissue (BAT), play an essential role in regulating whole-body energy homeostasis.
- Trial name
- NCT02159144
- Testing
- cold stress
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xiang Guang-da
Breast Cancer
Development of Gourmet Healthy Cooking Workshop for Cancer Patients
Subjects that participate in the practical workshop will improve their metabolic indexes, control their weight and improve their quality of life, in contrast to the participants that will take part in the nutritional consulting…
- Trial name
- NCT00364975
- Testing
- gourmet cooking workshop
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Potential Abnormality of Glucose Tolerance, Appetite; Lack or Loss, Nonorganic Origin
Short-term Effects of a Carob Snack on Postprandial Glycemic Responses and Energy Intake and Satiety
This study investigated any potential associations between two preloads offered as snacks and postprandial glycemic response, subjective and objective appetite and energy intake in healthy, normal-weight adults.
- Trial name
- NCT02935829
- Testing
- Glucose as reference food, White bread as reference food, Carob snack as test food
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Obesity, Normal Physiology
Energy Expenditure Responses to Different Temperatures
Background: The way that the body burns calories is known as energy expenditure. Some studies show that when we are cold, we burn more calories to keep our bodies warm.
- Trial name
- NCT01568671
- Testing
- Room temperatures
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)