Clinical trials: Healthy Controls
Ankle Instability, Healthy Controls
Acute Effect of Graded Motor Imagery on Ankle Rehabilitation: A Pilot Study
The primary aim of this study is to evaluate the immediate and short-term effects of the Graded Motor Imagery (GMI) method on individuals with chronic ankle instability (CAI).
- Trial name
- NCT07376915
- Testing
- graded motor imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa
Moral Development, Moral Dilemma
Moral Reasoning Intervention on Moral Justification Abilities
The primary aim of this study is to evaluate the short (immediate) and mid-term (one month) impact of moral (vs non-moral) reasoning interventions on the moral justification abilities in non-expert subjects.
- Conditions
- Moral Development, Moral Dilemma, Healthy Controls, Moral Justification
- Trial name
- NCT06735989
- Testing
- Lecture on moral reasoning, Lecture on logical reasoning
- Where
- Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Post-traumatic Stress Disorder, Psychological Trauma
Prevalence of Post-traumatic Stress Disorder and Trauma Symptoms in a General Population Sample
The goal of this observational study is to learn about how many people have post-traumatic stress disorder and related symptoms in the general population of people without any mental illness in the Barcelona region of Catalonia…
- Trial name
- NCT05679245
- Testing
- Assessment for exposure to psychological trauma and related symptoms
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Type 1 Diabetes Mellitus, Diabetic Ketoacidosis
Metabolic Effects of Exogenous 3-hydroxybutyrate in Patients With Type 1 Diabetes and Healthy Controls
The main objective of this clinical trial is to study the metabolic effects of intravenous infusion of the ketone body, 3-hydroxybutyrate (3-OHB), in patients with type 1 diabetes and healthy control subjects.
- Trial name
- NCT04656236
- Testing
- 3-hydroxybutyrate
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Renal Impairment
Study of a Single Intravenous (IV) Dose of MK-3402 in Participants With Impaired Renal Function and in Healthy Controls (MK-3402-004)
The purpose of this study is to compare the plasma and urine pharmacokinetics (PK) of MK-3402 in participants with impaired renal function and healthy control participants, to investigate the extent to which MK-3402 is removed…
- Trial name
- NCT04678505
- Testing
- MK-3402
- Where
- 2 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Patellar Tendinopathy
Bilateral Lower Limb Biomechanics During Side-Cutting in Unilateral Patellar Tendinopathy
Patellar tendinopathy (PT) is a common overuse injury in sports that involve jumping and directional changes. The biomechanical differences between individuals with PT and healthy controls during side-cutting, as well as whether…
- Trial name
- NCT07463560
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Diabetic Nephropathies
Nitric Oxide (NO) Activity and Diabetic Nephropathy
Experimental data suggest that oxidative stress and endothelial dysfunction are key players in the pathogenesis of diabetic nephropathy.
- Trial name
- NCT00136188
- Testing
- Folic Acid
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Kidney Transplant Infection, SARS-CoV Infection
Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) Immune Kidney Transplant Study (COVID-19)
None of the vaccines approved, or in clinical trials, have so far been tested on transplanted patients. If they produce an immune response to the Spike protein of SARS-CoV-2 it is unknown how long the protective immunity will…
- Trial name
- SCV-KTx-imm (NCT04747522)
- Testing
- SARS-CoV-2 vaccine
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Arginine Vasopressin Deficiency, Central Diabetes Insipidus
Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls
The study aims to investigate whether intranasal oxytocin (OXT) improves sexual well-being in patients with Arginine Vasopressin Deficiency (AVP-D).
- Conditions
- Arginine Vasopressin Deficiency, Central Diabetes Insipidus, Oxytocin Deficiency
- Trial name
- OxyPLEASURE (NCT06808516)
- Testing
- Oxytocin nasal spray
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Mental Disorders
Brain MRI (Magnetic Resonance Imaging) Scans of Patients With Treatment Resistant Depression (TRD) and Healthy Controls
Treatment resistant depression (TRD) is a major health concern, with 10% of patients with major depressive disorder not responding to conventional treatments.
- Trial name
- NCT01162434
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Cervical Cancer, Hpv
Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?
The purpose of the study is to understand if children with liver and kidney transplants develop the antibodies from the Gardasil vaccine.
- Conditions
- Cervical Cancer, Hpv, Warts
- Trial name
- NCT01101750
- Testing
- Quadrivalent HPV for types 6, 11, 16 and 18
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Kidney Transplantation, Multiparametric Magnetic Resonance Imaging
Multiparametric MRI in a Prospective Cohort of Living Kidney Donors, Recipients, and Healthy Controls: Correlations With Markers of Renal Function, Fibrosis and Ageing
Development of renal fibrosis is the irreversible culmination of various renal diseases and independently predicts adverse outcomes. Currently renal fibrosis can only be diagnosed by performing a renal biopsy.
- Conditions
- Kidney Transplantation, Multiparametric Magnetic Resonance Imaging, Living Donors, Renal Fibrosis
- Trial name
- MpRenal (NCT06210555)
- Testing
- Renal transplantation, Living kidney donation
- Where
- 2 sites in Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Patrick Schjelderup
Reliability, Validity of Measurement to Assess Lumbar Spine Motion, Comparison of Healthy Subjects and Low Back Pain Patients
Reliability of an Objective Measurement to Assess Lumbar Spine Motion in Healthy Controls and in Low Back Pain Patients
Main of the study is to assess the reliability of a new objective tool to measure lumbar spine motion. The data will be collected from healthy subjects and subjects with frequent or daily low back pain in the last three months.
- Trial name
- NCT03763994
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Controls, Healthy Control
Test-retest Reliability and Agreement of Trunk Muscle Activation in Pain-free Persons
The aim of the study is to investigate test-retest reliability and agreement of trunk muscle activation during functional tasks and clinical sensorimotor control tests in pain-free persons.
- Trial name
- MAS-Reliab (NCT06975202)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito: 2850m) to sea level on six-minute walking distance and scores in patients with pulmonary arterial hypertension PAH, who live permanently >2600m.
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, Six-minute Walk Test, High Altitude Effects
- Trial name
- NCT07804472
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
Multiple Sclerosis
Multiple Sclerosis and Respiratory and Functional Capacity
It is known that respiratory functions, physical activities and functional capacities of Multiple Sclerosis (MS) patients decrease with the progression of the disease.
- Trial name
- NCT05697523
- Testing
- Expanded Disability Status Scale, pulmonary function test, International Physical Activity Questionnaire - Short Form, 6 minute walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
SARS-CoV-2 Infection, Covid19
Respiratory Aerosols in Patients With COVID-19 and Healthy Controls
The proposed study will investigate respiratory aerosols in SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) positive and negative children and adults with the Resp-Aer-Meter (Palas GmbH).
- Trial name
- NCT04739020
- Testing
- Resp-Aer-Meter, Spirometry, Qualitative and quantitative virus PCR of respiratory secretions in patients with high aerosol concentrations
- Where
- Germany
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Pharmacokinetics, Neurology
A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Healthy Adult Subjects
The goal of this clinical trial is to assess the safety and effects of a crystalized form of lithium, AL001, when compared to commonly used Lithium Carbonate in healthy volunteers.
- Trial name
- NCT06921590
- Testing
- AL001, Lithium Carbonate Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alzamend Neuro, Inc.
Healthy Controls
[11C]Yohimbine PET Study of alpha2-AR
The main purpose of this study is to model tissue specific kinetics of [11C]Yohimbine in healthy male participants by positron emission tomography (PET) and the appropriate arterial input function (part A) ; to determine the…
- Trial name
- [11C]Yohimbine (NCT03520543)
- Testing
- [11C]Yohimbine, [11C]Yohimbine (Part B1) and [11C]Yohimbine + clonidine (Part B2)
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon