Clinical trials: Healthy Controls
Crohn's Disease, Ulcerative Colitis
Assessing the Drug Exposure Risk of Infants Breastfed by Women With Inflammatory Bowel Disease
Breastfeeding is beneficial to both mother and baby. However, many breastfeeding women are affected by long-term health conditions and need to take medications.
- Conditions
- Crohn's Disease, Ulcerative Colitis, Healthy Controls
- Trial name
- NCT03397108
- Testing
- The IBD group was divided into 2 subgroups: with or without anti-TNF antibody use
- Where
- 2 sites in Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Schizophrenia With Auditory Hallucinations
Frequency- and Intensity-Dependent After-Effects of High-Definition Transcranial Alternating Current Stimulation on Resting-State Electroencephalography
This study aims to investigate the after-effects of high-definition transcranial alternating current stimulation (HD-tACS) with varying parameters on resting-state brain activity in patients with schizophrenia experiencing…
- Trial name
- NCT07798804
- Testing
- high-definition transcranial alternating current stimulation(HD-tACS)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Hyperkyphosis, Viscoelasticity
Viscous Elastic Properties of Superficial Back Muscles in Individuals With Hyperkyphosis
Thoracic hyperkyphosis is a common spinal deformity that may alter the biomechanical and viscoelastic properties of trunk muscles.
- Trial name
- NCT07441213
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Sanko University
Asthma, Cystic Fibrosis
Breath Analysis in Children by New Point-of-care Instruments
In this study new hand-held devices for measuring exhaled breath will be tested in children with asthma, CF, and healthy controls. Main objectives will be feasibility and discriminative value of these techniques.
- Trial name
- NCT03377686
- Testing
- inflammation markers in exhaled breath
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Multiple Sclerosis
Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis
The investigators principal hypothesis is that INO and optic neuritis are objective, quantitative, and reproducible models for corroborating the hypothesis that changes in core body temperature are associated with the reversible…
- Trial name
- NCT00854750
- Testing
- ACTHAR
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elliot Frohman
Gastroparesis
GI-Challenge Study for Gastroparesis Patients and Healthy Controls
Gastroparesis Patients and Healthy Controls ages 20-49 will be asked to participate in an observational study measuring vagal activity following food ingestion in order to establish parameters of autonomic nerve/vagal function in…
- Trial name
- NCT03896126
- Testing
- Observational
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stroke, Acute
Exercise and RIC and TCD
The first week after a stroke is a particularly important time, as improving blood flow may limit secondary ischaemic damage to the brain and help reduce the overall burden neurological injury and future disability.
- Trial name
- NCT03968068
- Testing
- Exercise Procedure, Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Healthy Controls
Biomarker Assessment of Glutamatergic Target Engagement
The purpose of this study is to assess the relative feasibility of 2 potential functional measures of target engagement (Glx MRS, BOLD fMRI) to systematically assess mGluR 2/3 in drug development for psychotic spectrum disorders.
- Trial name
- NCT02134951
- Testing
- Ketamine, Normal saline
- Where
- 3 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Healthy, no Evidence of Disease, Lung Cancer
Molecular Markers in Predicting Lung Cancer Development Using Tissue Samples From Healthy Participants
RATIONALE: Studying samples of blood, urine, sputum, mouth cells, and bronchial tissue from healthy participants in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to…
- Trial name
- NCT00899457
- Testing
- proteomic profiling, biologic sample preservation procedure, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Healthy Volunteers
Strength and Balance in Gender- and Age-Matched Controls
The purpose of this study is to learn more about balance and strength in an elderly population (60 and older). Data will be compared between controls and the age/gender- matched PD participants in study "The Effects of vitamin D…
- Trial name
- VITDC (NCT02110875)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cholesterol, HDL, Lipid Metabolism, Inborn Errors
Mendelian Reverse Cholesterol Transport Study
The purpose of this study is to investigate the use of radiolabeled particulate cholesterol administered intravenously in association with albumin, as a method to study reverse cholesterol transport (RCT) in people carrying…
- Conditions
- Cholesterol, HDL, Lipid Metabolism, Inborn Errors, Tangier Disease, LCAT Deficiency
- Trial name
- NCT01782027
- Testing
- 3H-cholesterol bound to albumin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hepatic Impairment, Healthy
A Study to Evaluate Pharmacokinetics and Safety of Tegoprazan in Subjects With Hepatic Impairment and Healthy Controls
The main purpose of this study is to compare the pharmacokinetic and safety of tegoprazan following single oral dose in subjects with hepatic impairment versus healthy control.
- Trial name
- NCT04494269
- Testing
- Tegoprazan 50mg
- Where
- 3 sites in South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Specific Learning Disability, Healthy (Controls)
Neurotransmitter Levels in Children With Specific Learning Disorder
The aim of this clinical trial was to measure how specific neurotransmitter levels in children with Specific Learning Disorder (SLD) change compared to controls.
- Trial name
- SLD (NCT07240142)
- Testing
- Blood Product, Elisa test
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dilara Ulger Ozbek
Healthy
Local Metabolic Effects of Ghrelin in Skeletal Muscle and Adipose Tissue
The metabolic effects of ghrelin is investigated by microdialysis technique. Subjects are healthy young men. End points are interstitial concentrations of glucose, lactate, and glycerol.
- Trial name
- NCT01595373
- Testing
- Acyl ghrelin
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Esben Thyssen Vestergaard
Healthy Participants
Prefrontal Hemodynamics and Working Memory After Exhaustive Aquatic Exercise
This study compared prefrontal cortex hemodynamics and working memory performance following exhaustive aquatic exercise between endurance athletes and physically active individuals.
- Trial name
- NCT07837661
- Testing
- Incremental Exhaustive Aquatic Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Major Depressive Disorder, Healthy Controls
Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets
The study is investigating dysfunctions in neurocircuitry in regards to irritability with healthy controls (HC) and individuals with Major Depressive Disorder (MDD) by performing MRIs.
- Trial name
- UNIKET (NCT05046184)
- Testing
- Ketamine Hydrochloride, Midazolam injection
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Borderline Personality Disorder (BPD), Healthy Controls Group - Age and Sex-matched
Affect-based Impulsivity in Borderline Personality Disorder
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- NCT06880640
- Testing
- Stress Induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Vestibular Hypofunction, Bilateral Vestibular Hypofunction
Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation
The nervous system responds to changes in external or internal conditions by altering the behavior of neurons through multiple forms of neural plasticity.
- Conditions
- Vestibular Hypofunction, Bilateral Vestibular Hypofunction, Presbyvestibulopathy, Healthy Controls
- Trial name
- NCT06732440
- Testing
- Subthreshold Vestibular Conditioning, Balance Training, Balance Training Plus Subthreshold Conditioning
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Creighton University
Borderline Personality Disorder, Emotions
Emotional Reaction and Self Injury in Patients With Borderline Personality Disorder and Healthy Controls
The current study investigates the emotional response of patients with borderline personality disorder and healthy controls on stimuli associated with self-injury.
- Trial name
- NCT03149926
- Testing
- Stimuli presentation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Katharina Bachmann