Clinical trials: Healthy, open to volunteers
Healthy
Safety, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Ascending Doses BCD-261 in Healthy Subjects
The goal of this clinical trial is to investigate the safety, tolerability, pharmacodynamics, pharmacokinetics, and immunogenicity of BCD-261 after single subcutaneous injection at ascending doses and proposed therapeutic doses…
- Trial name
- NCT06715540
- Testing
- BCD-261, dose 1, BCD-261, dose 2, BCD-261, dose 3
- Where
- Russia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biocad
Healthy Adults, Natural Outdoor Environment
Blue-green Space Physical Activity: the "Parco Del Mare" Study
This study protocol, describe the innovative study intervention which will be performed in a green-blue space in Italy in order to investigate on the improvements in wellbeing following participation in the study.
- Conditions
- Healthy Adults, Natural Outdoor Environment, Health Promotion
- Trial name
- NCT06533943
- Testing
- Exercise program
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Healthy
REEF: Remote EEG Experiences With Families
The goal of this observational study is to learn about the usability of portable EEG sensors (REMI) in the home with infants and young children.
- Trial name
- REEF (NCT06733454)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York University
Healthy Volunteers
Advanced Clinical Practitioners in the ED
This study is designed to understand better how nurses, paramedics, and other healthcare professionals who have completed extra training to become Emergency Care Advanced Clinical Practitioners (EC-ACPs) work in emergency…
- Trial name
- NCT06355648
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy
Development of Novel MR Techniques Using Volunteer Participants
Using magnetic resonance (MR) imaging or spectroscopy as part of clinical research typically involves developing new MR protocols.
- Trial name
- NCT05943249
- Testing
- magnetic resonance
- Where
- United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University College, London
Healthy Aging
Exploring the Link Between Sleep and Brain Clearance
The purpose of this study is to assess the link between sleep and the clearance of waste products from the brain. This will be assessed in a group of healthy older adults.
- Trial name
- BBCDS (NCT05539378)
- Testing
- Auditory Stimulation
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Healthy Participants
Prevention of Hazardous Use of Alcohol with Danish High School Students (Our Choice)
The trial 'Our Choice' examines the effect of two prevention interventions targeting school, parent, and student levels at Danish high schools.
- Trial name
- NCT06018389
- Testing
- Structural only, Structural+Group MI
- Where
- Denmark
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy
Effects of an Antioxidant Supplement on Blood Vessel Health
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and the non-Hispanic Black (NHB) population is disproportionately affected.
- Trial name
- NCT06424756
- Testing
- MitoQ, MitoTempo, Tempol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Healthy, Adult Children
Effect of Practicing Yoga and Meditation on Cortisol Hormone, Immunoglobulin A and Metabolic Parameter Among Medical Students
This clinical trial aims to develop and test a yoga intervention to improve cortisol hormone rhythm, immunoglobulin A, and metabolic markers among medical students.
- Trial name
- GSY (NCT06661603)
- Testing
- GSY Yoga Intervention
- Where
- Hungary
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Healthy
Blood Collection for COM/BSBS
The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS)…
- Trial name
- NCT06082661
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Heart Failure, Cardiometabolic Syndrome
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
Positron emission tomography with 18F fluorodeoxyglucose (FDG) is the conventional imaging technique to provide information regarding tissue glucose uptake and has been highly clinically successful.
- Conditions
- Heart Failure, Cardiometabolic Syndrome, Cancer Diagnosis, Cardiovascular Diseases
- Trial name
- POLARIC-13 (NCT06645691)
- Testing
- Hyperpolarized 13C-pyruvate
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Healthy
Effects of a Placebo Probiotic on Gut Health and General Well-being in Individuals With Mild Gastrointestinal Symptoms
The present study is aimed at exploring whether positive expectations of receiving a three-week treatment with a probiotic supplement (in fact a placebo) improve symptoms of gastrointestinal distress and promote physical and…
- Trial name
- PlaCIBO (NCT06720558)
- Testing
- Control-no treatment
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Healthy
Beneficial Exposome Study
The purpose of this study is to explore the positive, holistic health outcomes resulting from regular exposure to naturally occurring compounds predicted to have health benefits.
- Trial name
- NCT06093464
- Testing
- Natural Compound A (Hinoki essential oil), Natural Compound B (Lemon essential oil), Natural Compound C (Control/Water)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Head and Neck Cancer, Healthy
Non-invasive Preoperative Tissue Evaluation in Head and Neck Tumor Patients Using Multispectral Optoacoustic Tomography (MSOT)
Multispectral Optoacoustic Tomography (MSOT) is a promising imaging technology that utilizes pulsed laser light. One of the key capabilities of this technology is measuring oxygenation within human tissue.
- Trial name
- msotcmfflap (NCT06716892)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Healthy
Effect of Flax in Yogurt on Blood Cyanide Levels
A randomized, controlled, cross-over post-prandial trial in healthy human volunteers will be conducted at the IH Asper Institute to determine the effect whole ground flaxseed, roasted then ground whole flaxseed, whole intact…
- Trial name
- NCT06491095
- Testing
- 0 g Flax, 40 g whole ground flaxseed, 40 g roasted then ground whole flaxseed
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Boniface Hospital
Older Adults, Web-based Intervention
Web-based Nursing Intervention to Promote Physical Activity Among Older Adults With Coronary Heart Disease
The purpose of this study is to develop and evaluate a web-based nursing intervention aimed at increasing physical activity in people aged 65 years and older with coronary heart disease.
- Conditions
- Older Adults, Web-based Intervention, Nursing, Healthy Lifestyle Habits
- Trial name
- NCT06197347
- Testing
- Web-based nursing intervention : Ch@ngeons Ensemble
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Healthy Volunteer Study
Safety Study of CZ10 in Healthy Volunteers
A randomized, double-blind, placebo-controlled, parallel group, dose escalation study in healthy subjects to evaluate the safety, tolerability, pharmacokinetics and initial effectiveness of a novel intravenous CT contrast…
- Trial name
- NCT06708767
- Testing
- Contrast Media
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nextrast, Inc.
Immune System Tolerance, Depression
ESAN II - Energy Sensing in Depression
The purpose of this study is to assess the effects of polyphenols from natural aronia juice on the immune system. Therefore, the study aims to distinguish the effects of natural juices that are rich in phytonutrients such as…
- Conditions
- Immune System Tolerance, Depression, Obesity, Microbial Colonization
- Trial name
- NCT05432362
- Testing
- Aronia Juice
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Juvenile Idiopathic Arthritis (JIA), Familial Mediterranean Fever (FMF )
Gait Profile and Variables in Pediatric Rheumatic Disease Using a Smart Insole System
In pediatric rheumatic diseases, joint swelling, effusion, tenderness, and painful restriction of joint movement, particularly in weight-bearing joints, frequently alter walking function.
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Familial Mediterranean Fever (FMF ), Healthy Controls
- Trial name
- NCT06705673
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy Subjects, Rheumatoid Arthritis
Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis
This study evaluates safety, tolerability, biodistribution and performance of the [68Ga]Ga-DOTA-Siglec-9 following a single intravenous administration in patients with active rheumatoid arthritis, vasculitis or pulmonary…
- Conditions
- Healthy Subjects, Rheumatoid Arthritis, Vasculitis, Pulmonary Sarcoidosis
- Trial name
- SIGLEC (NCT03755245)
- Testing
- [68Ga]Ga-DOTA-Siglec-9
- Where
- Finland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital