Clinical trials: Healthy
Femoro-acetabular Impingement
Single-center Comparative Study of Variation in Acetabular Anteversion According to Pelvic Tilt in Patients With Femoro-acetabular Impingement and Healthy Volunteers.
The main objective is to show that the upper acetabular anteversions calculated in standing, sitting, sitting hip in maximum flexion and supine positions are lower in patients with symptomatic DWI compared to healthy volunteers.
- Trial name
- VARIA-CFA (NCT05678894)
- Testing
- Scanner and EOS imaging
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Type II Diabetes
A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects
The trial is to assess the bioequivalence between HR20033 FDC tablet and co-administration of SHR3824 tablets and metformin XR tablets.
- Trial name
- NCT05108350
- Testing
- T1: FDC 5/500 mg; R1+R: SHR3824 5 mg + Metformin 500 mg XR, T2: FDC 5/1000 mg; R2+R: SHR3824 5 mg + two Metformin 500 mg XR
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Healthy
A Single Ascending Dose Escalation to Investigate Safety and PK of VVZ-149 Injection in Healthy Older Male Volunteers
The objective of this study is to investigate the safety, tolerability and pharmacokinetics (PK) of VVZ-149 injection after a single dose or loading/maintenance dose in healthy older male volunteers.
- Trial name
- NCT02333318
- Testing
- VVZ-149 injection
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vivozon, Inc.
Metabolic Syndrome, Pre-diabetes
Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia
The purpose of this study is to demonstrate the efficacy of pasteurized Akkermansia muciniphila (pAKK) in improving insulin sensitivity in hyperglycaemic, but otherwise healthy persons with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Pre-diabetes, Overweight and Obesity
- Trial name
- NCT05114018
- Testing
- Pasteurized A. muciniphila
- Where
- 2 sites in Germany, Ireland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- A-Mansia Biotech S.A.
Hypergastrinaemia
Effects of YF476 and Rabeprazole on Gastric Function
The primary objectives are to find out in healthy subjects if: YF476 prevents the ECL-cell hyperplasia induced by repeated doses of rabeprazole - a proton pump inhibitor; YF476 also prevents rebound hyperacidity after stopping…
- Trial name
- NCT01699113
- Testing
- YF476, Rabeprazole
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Histamine Induced Itch
A Study To Investigate The Effect of JNJ-39758979 on Histamine Induced Itch in Healthy Male Volunteers
The purpose of this study is to investigate the effect of JNJ-39758979 compared to placebo on histamine induced itch in healthy male volunteers.
- Trial name
- NCT01068223
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy Volunteer
A Study of RO4995819 to Assess Bioavailability and Safety in Healthy Volunteers
This randomized, open-label, cross-over study will assess the bioavailability and safety of RO4995819 in healthy volunteers. Volunteers will receive two different formulations (tablet and capsule) of the study drug under fed and…
- Trial name
- NCT01901159
- Testing
- RO4995819
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy Normal Athletes
A Randomized, Placebo Controlled Trial of L Max in Healthy Adult Athletes
The goal of this study is to evaluate the lung-cleansing effects of L Max by measuring changes in Participant Reported Outcome (PRO) Scores and athletic performance.
- Trial name
- NCT07102680
- Testing
- L Max
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Climatic, Inc.
Asthma, Atherosclerosis
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
Background: Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation.
- Conditions
- Asthma, Atherosclerosis, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT01143480
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Cardiovascular, Healthy Subjects
A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin
The study aims to compare blood pressure and pulse in male healthy subjects taking mirabegron and tamsulosin both alone and in combination.
- Conditions
- Cardiovascular, Healthy Subjects, Pharmacokinetics
- Trial name
- NCT01489696
- Testing
- mirabegron, tamsulosin
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy
Effects of Salvinorin A in Healthy Controls
This study evaluates the effects of Salvinorin A (SA). SA is the active ingredient of the plant Salvia divinorum that is known to have been used by Mexican Indians as part of religious rituals.
- Trial name
- NCT00700596
- Testing
- Salvinorin A
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Yale University
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Influenza
A Study Evaluating the Safety and Tolerability of a Seasonal Influenza Vaccine Containing LIQ001
This study is designed to evaluate the safety, tolerability, and immune response of LIQ001 mixed with a commercially available seasonal influenza vaccine (Fluzone) in two populations of subjects; healthy adult subjects 18 to 49…
- Trial name
- LIfT (NCT01224262)
- Testing
- Fluzone® (2010/2011 Inactivated Trivalent Influenza Vaccine), LIQ001 (0.45mg), LIQ001 (1.8mg)
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Liquidia Technologies, Inc.
Healthy
A Relative Bioavailability Study of Ramipril 10 mg Capsules Under Fed Conditions
To compare the rate of absorption and oral bioavailability of a test formulation of Ramipril10 mg Capsules manufactured by Purepac Pharmaceutical Company to an equivalent oral dose of the commercially available reference product…
- Trial name
- NCT00864162
- Testing
- Ramipril10 mg Capsules, single dose, Atlace® 10 mg capsules, single dose
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Healthy Volunteers
A Safety Study of Mebendazole in Children 2 to 10 Years of Age
The purpose of this study is to assess the safety and tolerability of mebendazole 500-mg chewable tablet formulation in a pediatric population.
- Trial name
- NCT01173562
- Testing
- Mebendazole
- Where
- Tanzania
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy
A Study in Healthy Men to Test How BI 690517 is Taken up and Handled by the Body
The trial is intended to investigate the basic pharmacokinetics, excretion pathways and metabolism of BI 690517 and its metabolites.
- Trial name
- NCT05515588
- Testing
- BI 690517 (C-14), BI 690517
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Bioequivalence of Duvelisib and Food Effect on Pharmacokinetics of IPI-145
To Evaluate the Bioequivalence of the two formulations of IPI-145 and the Effect of Food on the Pharmacokinetics of IPI-145
- Trial name
- NCT02307461
- Testing
- IPI-145 (duvelisib), IPI-145
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- SecuraBio
Healthy
A First in Human Trial Evaluating THB335 in Healthy Participants
This study is a double blind, randomized, placebo-controlled, Phase 1 study in three parts: single ascending doses and food effect (Part 1), multiple ascending doses (Part 2) and Relative Bioavailability of Two Formulations (Part…
- Trial name
- NCT06425861
- Testing
- THB335 single dose, THB335 fasted/fed, THB335 multiple dose
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Third Harmonic Bio, Inc.
Healthy
A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants
The purpose of this study was to evaluate and compare the plasma pharmacokinetic profiles of ACH-0144471 (danicopan) in healthy participants after administration of single oral doses of modified release prototype formulations.
- Trial name
- NCT03384186
- Testing
- Danicopan Modified Release Prototype 1, Danicopan Modified Release Prototype 2, Danicopan Modified Release Prototype 3
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
Healthy
Neural Adaptations to Metronome-Paced Strength Training
The aim of the study is to investigate the effects of incorporating variability within Resistance Training (RT) methods on the neural adaptations along the corticospinal tract and on neuromuscular function.
- Trial name
- NCT06532786
- Testing
- Fractal Paced, Isochronous Paced, Self Paced
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
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