Clinical trials: Healthy
Non-specific Chronic Low Back Pain, Healthy Volunteer
Behavioral Indicators of Pain Representation
The goal of this observational study is to compare the postural response to the mental simulation of everyday situations identified as painful in participants with non-specific low back pain and healthy volunteers.
- Trial name
- ICOR (NCT06669767)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Neurofeedback, Cognitive Training
Neurofeedback Removal of Emotional Information From Mind
This project will examine whether individuals can be trained, using real-time feedback about brain function during neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to…
- Conditions
- Neurofeedback, Cognitive Training, Memory, Short-Term, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- remtrain (NCT06460207)
- Testing
- fMRI neurofeedback
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Nausea and Vomiting, Chemotherapy-Induced
A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults
Casopitant may affect liver enzymes that metabolize ketoconazole. This study is designed to test the safety and the extent of the Casopitant affect on ketoconazole levels in healthy human subjects.
- Trial name
- NCT00460707
- Testing
- Casopitant 150 mg, Ketoconazole, Casopitant 50 mg
- Where
- 3 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza
Phase 1b Influenza Vaccine Study in Healthy Subjects
The purpose of this study is to see whether a single vaccination (injection) with the investigational influenza vaccine is safe in healthy subjects.
- Trial name
- NCT01181336
- Testing
- Influenza vaccine (FLU-v), FLU-v Control
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- PepTcell Limited
Solid Tumours
A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine
This will be an open-label, randomised, 2 part (Part A and Part B), 2 treatment (savolitinib alone or in combination with famotidine), crossover study in healthy, non Japanese, male subjects, performed at a single study centre.
- Trial name
- NCT04179071
- Testing
- Savolitinib, Famotidine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Leishmaniasis
Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults
The goal of this interventional study is to assess the safety and tolerability of OlPC and to characterize the pharmacokinetics (PK) of OlPC following single, ascending doses administered orally in healthy-fed subjects.
- Trial name
- NCT06124144
- Testing
- Oleylphosphocholine
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Healthy
Bioavailability Study of Prodrug of GLPG0187 in Healthy Volunteers
The purpose of this study is to evaluate the amount of GLPG0187 present in the blood (pharmacokinetics) after a single oral dose of the prodrug of GLPG0187 given to healthy subjects.
- Trial name
- NCT01580644
- Testing
- GLPG0187 prodrug
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
FED
Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Non-Fasting Conditions
To compare the bioavailability and characterise the pharmacokinetic profile of the sponsor's test formulation with respect to the reference formulation Cellcept® 500 mg tablets, in healthy, adult, human male subjects under…
- Trial name
- NCT01283867
- Testing
- Mycophenolate Mofetil
- Where
- India
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Adult, Cyclists
Musculotendinous Adaptations to Strength and Endurance Training in Cyclists
This study investigated whether adding strength training to regular endurance training improves performance and muscle function in competitive cyclists.
- Conditions
- Healthy Adult, Cyclists, Athletes
- Trial name
- STEND (NCT07658300)
- Testing
- Strength training, Endurance training
- Where
- Lithuania
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Healthy
Cognitive Impact of Paracetamol in Healthy Volunteers
Randomized study, double-blind, crossover, controlled versus placebo.
- Trial name
- ICP (NCT01390467)
- Testing
- Cantab®
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Interaction Between ABT-335, Rosuvastatin and Warfarin
This is a multiple-dose, double-blind, randomized, single-center, parallel-group study in adult male subjects in general good health.
- Trial name
- NCT00487136
- Testing
- Warfarin, warfarin plus ABT-335 plus rosuvastatin 5 mg, warfarin plus ABT-335 plus rosuvastatin 20 mg
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Lymphedema of Upper Limb
MRL in the Upper Extremity
Objective: The aim of this study is to examine the feasibility and applicability of the MRL protocol for the upper extremity in Maastricht University Medical Center, and to examine the differences of the lymphatic system between…
- Trial name
- NCT04575636
- Testing
- Magnetic Resonance Lymphography
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Volunteer, Renal Impairments
A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects
The purpose of this trial is to compare the pharmacokinetic characteristics and safety of YHD1119(Pregabalin SR 75mg) and YHD1119(Pregabalin SR 150mg) in subjects with renal impairment and healthy subjects.
- Trial name
- NCT05012436
- Testing
- YHD1119 75mg
- Where
- 2 sites in South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yuhan Corporation
Healthy
The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects
A randomized,double-blind,placebo-controlled,single-ascending dose phase Ⅰa study to evaluate the safety,tolerability,pharmacokinetics and pharmacodynamics of STSA-1002 following intravenous infusion in healthy subjects
- Trial name
- NCT05032144
- Testing
- STSA-1002 injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Advanced Chronic Liver Disease, Healthy Participants
A Study to Investigate the Pharmacokinetics of AZD2389 in Healthy Participants When Administered Alone and in Combination With Quinidine
The purpose of this study is to assess the pharmacokinetics (PK) and safety of AZD2389 when administered alone and in combination with quinidine in healthy participants.
- Trial name
- NCT06974565
- Testing
- AZD2389, Quinidine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Papillomavirus Infections
Safety, Tolerability and Immunogenicity of HPV (Human Papilloma Virus) Vaccine in Healthy Females 9 to 15 Years of Age in India (V501-029)
The purpose of this study is to evaluate the safety and tolerability of the Quadrivalent Human Papilloma Virus (HPV) vaccine in healthy females 9 to 15 years of age in India.
- Trial name
- NCT00380367
- Testing
- Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy
A Study to Assess the Safety and Pharmacokinetics of a Single Intravenous Administration of CNTO 328 Derived From 2 Different Cell Lines in Healthy Participants
The purpose of Part 1 of this study is to assess the safety and tolerability of 2 dose levels (1.4 and 2.8 mg/kg) of CHO-derived CNTO 328 and Sp2/0-derived CNTO 328.
- Trial name
- NCT02074800
- Testing
- CNTO 328 (Sp2/0-derived), CNTO 328 (CHO-derived)
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Healthy Volunteer
A Pharmacokinetic And Bioavailability Study of Intravenous Danoprevir in Healthy Volunteers
This three-part study will evaluate the pharmacokinetics and bioavailability of intravenous danoprevir with and without low-dose oral ritonavir, and the effect of oral cyclosporine on the pharmacokinetics of intravenous…
- Trial name
- NCT01654211
- Testing
- danoprevir, ritonavir
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
BRAN Pilot Study: Metabolic Signature of Wheat Bran Related to Gut Fermentation in Humans
It is a pilot study, conducting on 6 healthy women and aiming at defining new biomarkers related to wheat bran fermentation. For this, a breakfast, containing 5 biscuits enriched in 13-C wheat bran (which grown under 13-CO2…
- Trial name
- FITABLE (NCT03717311)
- Testing
- Nutritional Intervention
- Where
- France
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy
Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study
The purpose of the study is to gain a better understanding of mechanoreceptors in the PIP joint ligamento-muscular reflexes and their role is.
- Trial name
- NCT01456871
- Testing
- Guided insertion of electrodes, Electromyographic (EMG) recording
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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