Clinical trials: Healthcare Utilization
Immune Thrombocytopenia
A Real World Study of Treatment Patterns and Effectiveness of Standard of Care in Primary Immune Thrombocytopenia Patients
The aim of this study was to describe real-world treatment patterns and standard of care treatment effectiveness and utilization outcomes in adult primary ITP patients indicated for second-line treatment with any prior…
- Trial name
- NCT07805408
- Where
- United States
- Volunteers
- 3,714 people
- Sponsor
- Novartis Pharmaceuticals
Headache
Utilization of 60-Day Peripheral Nerve Stimulation of the Occipital Nerves for the Treatment of Headache
This prospective observational cohort study will evaluate clinical outcomes and health care resource utilization among adults who, independent of research participation, are clinically scheduled to undergo temporary 60-day…
- Trial name
- NCT07553533
- Testing
- Occipital nerve peripheral nerve stimulation (PNS)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Yale University
Vaccination Refusal, Vaccine Hesitancy
Educational Videos to Address Vaccine Hesitancy in Childhood Immunization
Vaccine hesitancy and the COVID-19 pandemic may threaten immunization coverage in children. This study aimed to evaluate the tailored educational videos to reduce vaccine hesitancy and analyze immunization completeness status.
- Trial name
- NCT05390697
- Testing
- Educational videos
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Asthma
Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care
ANCHOR is a prospective, phase IV, interventional, single-arm, open-label study of 1,500 adult participants with symptomatic asthma requiring the use of rescue therapy aimed to compare the asthma exacerbation rates before and…
- Trial name
- ANCHOR (NCT06422689)
- Testing
- Albuterol and budesonide inhalation aerosol
- Where
- 11 sites in United States
- Volunteers
- 1,511 people
- Sponsor
- AstraZeneca
Medication Non-adherence
Improving Adherence and Outcomes by Artificial Intelligence-Adapted Text Messages
Uncontrolled hypertension is a major cause of morbidity and mortality and many patients fail to take their antihypertensive medication as prescribed.
- Trial name
- AIM@BP (NCT02454660)
- Testing
- SMS (Text messages)
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 1
ANAIS, a Spanish Version of the DAFNE Programme
ANAIS is a therapeutic education programme for type 1 diabetes based on a flexible insulin regime adjusted to the patient's food intake.
- Trial name
- ANAIS (NCT03699189)
- Testing
- Immediate ANAIS
- Volunteers
- 80 people
- Sponsor
- Rosa María Sánchez Hernández
Patient Participation
Using Patient Feedback in Mental Health Services
Aim: This study aims to assess how feasible and acceptable it is to deliver facilitated team meetings, designed to support mental health teams to listen and learn from patient feedback and how helpful and feasible the evaluation…
- Trial name
- NCT05603325
- Testing
- Person Centered Practice, Interview
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- NHS Grampian
Coronavirus, Covid19
Impact of Aerosol Box Use on Healthcare Provider Contamination
Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses.
- Conditions
- Coronavirus, Covid19, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04880668
- Testing
- Aerosol Box (Splashguard)
- Where
- 4 sites in United States, Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Breast Cancer, Breast Neoplasms
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
Phase 4 of the Carolina Breast Cancer Study (CBCS4) builds on prior phases that examined molecular and epidemiologic differences in breast cancer types and outcomes.
- Trial name
- NCT07214610
- Testing
- Structured behavioral intervention
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Tuberculosis, Latent Tuberculosis
Use TST and QFT-RD1 Test to Monitor the Tuberculous Infection in Patients, Close Contact People and Health Care Workers
Tuberculosis is still the most common infectious disease in Taiwan. The infants in Taiwan have been vaccinated at birth with BCG -Tokyo 171 strain since 1951.
- Conditions
- Tuberculosis, Latent Tuberculosis, Tuberculosis Contact, Elderly
- Trial name
- NCT00311220
- Testing
- tuberculin for skin test
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study B)
To assess the effectiveness of social comparison in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02148523
- Testing
- Comparison to peers, Adherence feedback, Electronic pill bottle
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Patient Compliance, Mobile Applications
Reminder Strategies to Improve Meal-Logging Adherence
This study is a single-center micro-randomized trial, aiming to examine the effects of two theory-driven reminder strategies on adherence to repeated, image-based meal logging in adults age 45 and older.
- Conditions
- Patient Compliance, Mobile Applications, Reminder Systems
- Trial name
- NCT07555262
- Testing
- Loss-Framed Reminder, Logging Consistency Reminder, Neutral Reminder
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of St.Gallen
Side Effects of Creatine Monohydrate Dosing
Gastrointestinal and Fluid Retention Symptoms Associated With Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation
This study aimed to investigate the incidence and severity of GI symptoms associated with daily CM supplementation, with and without a loading phase, in healthy male and female adults.
- Trial name
- NCT07176325
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Patient Compliance, Patient Adherence
Motivational Interviewing to Support Oral AntiCoagulation Adherence in Patients With Non-valvular Atrial Fibrillation (MISOAC-AF)
The purpose of the study is to investigate the impact of motivational interviewing in the adherence of patients with AF to oral anticoagulation (OAC) regimens.
- Trial name
- MISOAC-AF (NCT02941978)
- Testing
- Motivational interview, Control
- Where
- Greece
- Volunteers
- 1,140 people
- Sponsor
- AHEPA University Hospital
Opioid Use Disorder (OUD), Chronic Pain
Opioid Adherence and Support Through Innovative Texting Strategies
The goal of this clinical trial is to examine the effects of reminder and mindfulness text messages on medication adherence and managing craving, pain, and withdrawal symptoms in people taking medications for opioid use disorder…
- Trial name
- OASIS (NCT07350148)
- Testing
- Mindfulness text messages
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Systemic Lupus Erythematosus
Reducing Disparities in Medication Adherence in SLE
This is a pilot study to assess the feasibility of using Surescripts refill data during the clinical encounter to improve medication adherence in patients with systemic lupus erythematosus
- Trial name
- NCT03738826
- Testing
- Behavioral Intervention
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Duke University
Hypertension, Uncontrolled Hypertension
Addressing Medication Non-adherence in Patients With Poorly Controlled Hypertension Using Urine Mass Spectrometry
Hypertension is the single largest contributor to cardiovascular disease and death. While adequate control of hypertension reduces risk of disease, many patients have uncontrolled hypertension.
- Conditions
- Hypertension, Uncontrolled Hypertension, Non-Adherence, Medication
- Trial name
- ADURINE (NCT06938633)
- Testing
- mass spectrometry analysis
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Changi General Hospital
Obesity & Overweight, Obesity
Genetic, Microbiological and Behavioral Factors in Obesity
This study will assess the impact of genetic markers, microbiological (microbiome) and behavioral factors on tolerance, adherence and effectiveness of dual GLP1/GIP RA in the treatment of obesity.
- Conditions
- Obesity & Overweight, Obesity, Genetics
- Trial name
- OPTIMIZE-GEN (NCT07650149)
- Testing
- genetic polymorphism, gut microbiome
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Diabetes Mellitus, Type 2
Evaluation of a Patient Portal Intervention for Diabetes: A Pilot Randomized Controlled Trial
The purpose of this study is to conduct a two-arm, parallel-design, pragmatic randomized controlled trial of a patient portal intervention for diabetes, My Diabetes Care, to evaluate its effect on patient activation and secondary…
- Trial name
- NCT03947333
- Testing
- My Diabetes Care
- Where
- United States
- Volunteers
- 287 people
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer
Evaluation of the Impact of a Pharmaceutical Interview on the Adherence to Hormonotherapy in Women With Breast Cancer
Breast cancer is the first cancer in women and 60% of new cases occurring in women 50 to 74 years old. With about 50,000 new cases, it is the second cancer the most serious cancers.
- Trial name
- HORMONOVILLE (NCT04142476)
- Testing
- interview
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Centre Georges Francois Leclerc