Clinical trials: Health Risk Behaviors
Microbiome Analysis, Drug Abuse in Pregnancy
Alcohol and Cannabis Use Among Pregnant Slovenian Women
The aim of the study is to determine the prevalence of alcohol and drug use among Slovenian pregnant women. Alcohol and drug use during pregnancy has significant effects on the foetus and has short- and long-term health…
- Conditions
- Microbiome Analysis, Drug Abuse in Pregnancy, Alcohol Abuse in Pregnancy, Health Behavior, Risky
- Trial name
- NCT07456579
- Where
- Slovenia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Adolescent Sexual Risk Behaviors
Effects of a Worksite Parenting Program
Many adolescents in the U.S., even very young adolescents, are engaging in sexual risk behaviors that put them at risk for sexually transmitted diseases (STDs) and unintended pregnancy.
- Trial name
- NCT00465010
- Testing
- Talking Parents, Healthy Teens
- Where
- United States
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- RAND
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Human Immunodeficiency Virus Infection, Sexually Transmitted Diseases
Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African Men
Sub-Saharan Africa has about 10% of the world's population, but was home to more than 60% of all people living with HIV in 2003.
- Trial name
- NCT01490359
- Testing
- Men Making a Difference HIV/STD Risk Reduction Intervention, Health Promotion Control
- Volunteers
- 1,181 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking
Risk Perception Among Quitting Smokers
The goal of this behavioral research study is to put together and study a treatment for nicotine dependence that looks at how participant's thoughts and feelings about smoking may be related to how successfully they quit smoking.
- Trial name
- NCT00384696
- Testing
- Nicotine Replacement Therapy, Questionnaire
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Health Behavior, Genetic Information
The DNA-Based Lifestyle Enhancement Trial
Despite the known cardiovascular benefits of regular physical activity and having a balanced diet, it has proven challenging to change health behaviours towards favourable lifestyles.
- Conditions
- Health Behavior, Genetic Information, Cardiovascular Risk Factor
- Trial name
- DNAble (NCT03583983)
- Testing
- Personalized Health Recommendations, Generic Health Recommendations
- Where
- Canada
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Healthy Population
Italian Digital Primary Cardiovascular Prevention Study
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular…
- Trial name
- CV-PREVITAL (NCT05339841)
- Testing
- Mobile health application
- Where
- 32 sites in Italy
- Volunteers
- 27,520 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Cardiovascular Diseases, Cardiovascular Risk Factor
Secondary Care - Prescribing Lifestyle Adjustments for Cardiovascular Health (S-PLAC 2)
Prescribing lifestyle changes to patients who have cardiovascular disease (CVD) may be an extremely cost effective mechanism of improving health individually and for the NHS.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Health Behavior
- Trial name
- S-PLAC 2 (NCT04118673)
- Testing
- Lifestyle Prescription (LRx)
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Parent-Child Relations
Parent-child Communication and Health-risk Behavior
Engaging in health-risk behaviors such as tobacco and alcohol use put youth at risk for health problems that may compromise their futures and are extremely costly to society.
- Trial name
- MP (NCT02330666)
- Testing
- Mission Possible: Parents & Kids Who Listen
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Prostate Cancer
An Epidemiological Study of Genetic Risk Factors for Prostate Cancer in African-American and Caucasian Males
This study will examine the association of genetic variants and gene expression patterns with the risk of prostate cancer. There will be (It will include?) genotype analysis of blood DNA from 600 patients with the disease and…
- Trial name
- NCT00342771
- Where
- 2 sites in United States
- Volunteers
- 2,033 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Stress Resilience, Blood-Brain Barrier Integrity
Role of the Blood-Brain Barrier in Stress Resilience: Investigating New Pathways Towards Pharmacological Augmentation of Stress Resilience
The goal of this clinical trial is to better understand the relationship between blood-brain barrier (BBB) function and stress resilience and to investigate a potential causal role for BBB function in stress resilience in humans.
- Conditions
- Stress Resilience, Blood-Brain Barrier Integrity, Mental Health
- Trial name
- PHASR-PP (NCT06965868)
- Testing
- Metformin
- Where
- 3 sites in Germany, Poland and 1 more
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Resilienzforschung (LIR) gGmbH
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Medication Adherence
Daily Delivery and Supervision of Psychotropic Medication for High-Risk Patients With Severe/Persistent Mental Illness
The main study intervention is the daily witnessing of participant self-administration of medications by trained pharmacy staff to ensure compliance.
- Trial name
- NCT03766503
- Testing
- Daily
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Oral Health
Caries-Obesity Prevention in Children by Modifying Risk Behaviors Among Parents With Immigrant Background-COP Study
Immigrants constitute 18.2 % of the whole population in Norway. Health inequalities were previously reported, and immigrant status has been associated with a high risk of caries and obesity in children.
- Trial name
- COP (NCT05758454)
- Testing
- Caries and Obesity Prevention
- Where
- 2 sites in Norway
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Oral Health Centre of Expertise in Western Norway
Soccer Training, Body Composition
The Influence of Football Training as a medicine_FIM_UTH
The purpose of this randomized controlled study will be to inestigate the relationship between recreational football training at various training volumes and the health responses of middle-aged participants at high risk for…
- Conditions
- Soccer Training, Body Composition, Physical Activity, Healthy
- Trial name
- FIM (NCT05273203)
- Testing
- FIM-1, FIM-2, FIM-3
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Obesity Prevention, Obesity
Effectiveness of Tailored Multichannel Interventions on Weight Loss Among Adolescents: A Randomized Controlled Trial
overweight among adolescents is a public health issue. However, several weight loss interventions were developed and conducted for adolescents.
- Conditions
- Obesity Prevention, Obesity, Overweight Adolescents, Overweight/Obesity, Adolescent
- Trial name
- NCT06767072
- Testing
- Tailored Multichannel interventions
- Where
- Egypt
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Cairo University