Clinical trials: Health Options
Depression
Mental Health Intervention for Elderly Abuse Victims
There is no current elder abuse service that systematically assesses and provides services to address the mental health needs of older adult abuse victims.
- Trial name
- PROTECT (NCT02283385)
- Testing
- PROTECT
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Weill Medical College of Cornell University
Dental Cements
Resin-Cement Type Influence on Cement Remnants in Implant-Supported Restorations
This study quantitatively compared cement residues of two resin cement types around implant-supported restorations (ISR) with a crown-abutment margin located at the gingival level.
- Trial name
- NCT06711237
- Testing
- self-adhesive resin cement (RC), resin-modified glass-ionomer cement (RMGIC)
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Vilniaus Implantologijos Centro (VIC) Klinika
Menstrual Regulation, Menstrual Health Intervention
Period Pills for Menstrual Regulation: A New Reproductive Health Option
The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.
- Trial name
- Period Pills (NCT07671989)
- Testing
- Mifepristone + Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Refractory Ischemia
Quality of Life in Patients With Refractory Angina
The health and well being of patients with refractory angina will be assessed using validated questionnaires (SF-36 and Seattle Angina Questionnaire [SAQ]) at baseline and one year.
- Trial name
- NCT00840437
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Minneapolis Heart Institute Foundation
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Implementation Strategy Bundles for Structured Follow-up
Testing the Impact of the MOHR Follow-up Support
This study will evaluate the impact of 3 different strategies to increase engagement of participants in My Own Health Report (MOHR) and health behavior change activities over time.
- Trial name
- NCT07569224
- Testing
- Providing reminder and resources via messages, Reminder and resources sent via navigation, Regular care
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Body Weight
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
Sugar-sweetened beverages (SSBs) contribute an alarming ~7% of calories in the US diet among adults, making SSBs the single largest source of added sugar.
- Trial name
- SUB-POP (NCT04567108)
- Testing
- Maintain usual SSBs, Substitute to non-SSBs, Study app
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
HIV/AIDS
The Prevention Options for Women Evaluation Research (POWER) Cohort
The POWER Cohort study is a PrEP implementation project to demonstrate Pre-exposure prophylaxis (PrEP) delivery for young women in Cape Town and Johannesburg, South Africa and Kisumu, Kenya.
- Trial name
- NCT03490058
- Testing
- Truvada
- Where
- 3 sites in Kenya, South Africa
- Volunteers
- 2,255 people, healthy volunteers welcome
- Sponsor
- University of Washington
Smoking Cessation
Enhancing Smoking Cessation Via Telehealth Options in Primary Care
The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- E-STOP (NCT05493254)
- Testing
- Smoking cessation e-visit, Treatment As Usual
- Where
- United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions
Plant vs Animal-based Protein Sources as an Anabolic and Metabolic-protective Options for SO in Older Adults
This study is testing how different types of protein - from red meat, legumes (like lentils and beans), or a mix of both - affect muscle strength, body composition, and metabolic health in older adults with obesity who are also…
- Conditions
- Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions, Obesity (Body Mass Index >30 kg/m2), Sarcopenia
- Trial name
- NCT07030738
- Testing
- Legume-Based High-Protein Diet + Resistance Training, Meat-Based High-Protein Diet + Resistance Training, Mixed Legume and Meat High-Protein Diet + Resistance Training
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Apnea
Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers
Previous studies have shown that programs encouraging the use of OSA treatments can help patients use these treatments more often, but the improvement is usually modest.
- Trial name
- BOOST (NCT07207473)
- Testing
- Behavioral strategy program X plus Y, Behavioral strategy program X
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Contraception
Evaluation of a Peer Education Program to Promote Family Planning Among Female Sex Workers in Kenya
-Purpose: To develop and evaluate an intervention designed to improve consistent contraceptive use and dual method use in particular, among female sex workers (FSWs) in Rift Valley Province in Kenya.
- Trial name
- NCT01957813
- Testing
- Lifestyle Counseling, Standard Health Services
- Where
- 2 sites in Kenya
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- FHI 360
Traumatic Brain Injury
Traumatic Brain Injury; Needs and Treatment Options in the Chronic Phase
Traumatic brain injury (TBI) is a condition affecting the persons' central nervous system with a need for extensive and highly specialized initial health care provision followed by comprehensive rehabilitation efforts.
- Trial name
- NCT03545594
- Testing
- Patient-centered in home rehabilitation, Control
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Food Choice, Implementation Science
Healthy Options At Pantries (HOAP) Study
This study will evaluate a digital nudge intervention, Healthy Options At Pantries (HOAP), in the online food pantries of three large charitable food organizations.
- Conditions
- Food Choice, Implementation Science, Food Insecurity, Diet, Healthy
- Trial name
- HOAP (NCT07729436)
- Testing
- Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Liver Tumor
Is Thoracic Paravertebral Block a Better Option Than Conscious Sedation for PRFA of Liver Tumors
Percutaneus radiofrequency ablation (RFA) of liver tumors causes acute pain during the periooperative setting. In order to facilitate tumor access, patient should collaborate with a surgeon during the procedurę, therefore should…
- Trial name
- NCT04241887
- Testing
- thoracic paravertebral blockade, local anaesthesia
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- University of Warmia and Mazury
Uterine Cervical Neoplasms, HPV Testing
Human Papillomavirus (HPV) Self-Sampling Options to Promote Equity
This study is testing a new way to help people who are unhoused get screened for cervical cancer. Cervical cancer can often be prevented if it is found early.
- Conditions
- Uterine Cervical Neoplasms, HPV Testing, Pap Smear
- Trial name
- HOPE (NCT07214506)
- Testing
- Human papillomavirus Self-collection, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Pain Perception, Patient Satisfaction
Lavender Aromasticks for Pain Control
The purpose of this randomized pilot study is to collect preliminary data on the impacts of lavender essential oil aromatherapy on the patient-reported quality of pain management provided for the vascular surgery patient…
- Trial name
- NCT04396444
- Testing
- Aromastick
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Overweight and Obesity
Teaching Obesity Treatment Options to Adult Learners Intervention Via VA Video Connect
The goal of this study is to assess the feasibility and acceptability of Teaching Obesity Treatment Options to Adult Learners (TOTAL intervention), which includes an educational video about obesity treatment options within VA in…
- Trial name
- TOTAL (NCT04878289)
- Testing
- TOTAL with Motivational Telemedicine Sessions
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Chronic Pain, Back Pain
Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain
The goal of this clinical trial is to learn which treatment works better for veterans with chronic neck or back pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT)…
- Conditions
- Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
- Trial name
- POWeR (NCT07137715)
- Testing
- Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Colorado, Denver