Clinical trials: Health Aging
Obesity
Females, Aging, Metabolism, and Exercise
This study is designed to determine whether a reduction in hormones (such as occurs during menopause) causes a decrease in calories burned during physical activity.
- Trial name
- FAME (NCT01712230)
- Testing
- GnRH agonist, Supervised cardiovascular exercise
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Mobility Limitation
BAILA: Being Active, Increasing Latinos Healthy Aging
Investigators propose a randomized controlled trial (RCT) to test the efficacy of the revised 4-month BAILAMOS© program for improving lifestyle PA and health outcomes (physical and cognitive function, self-reported functional…
- Trial name
- BAILA (NCT01988233)
- Testing
- BAILAMOS© Dance Program, Health Education Control Group
- Where
- 12 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sedentary Lifestyle
Exercise Effects on Brain Health and Learning From Minutes to Months
Given the accelerating growth of older adults worldwide and the decline in cognitive function with aging, therapeutics that remediate age-related cognitive decline are needed more than ever.
- Trial name
- EXTEND (NCT03114150)
- Testing
- Cardiorespiratory fitness training, Functional fitness training
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Michelle W. Voss
Aging, Sarcopenia
Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health
What are the effects of resistance exercise (RE) alone or RE plus low intensity physical activity (LPA) breaks in sedentary time (ST) on skeletal muscle health in older adults? What are the effects of resistance exercise (RE)…
- Conditions
- Aging, Sarcopenia, Disability Physical, Cardiovascular Diseases
- Trial name
- REALPA (NCT03771417)
- Testing
- Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Activities of Daily Living, Accidental Fall
Bingocize: A Novel Mobile Application for Older Adult Health
This study tests the effectiveness of using a new mobile application (Bingocize®) to improve older adults' (a) adherence to an engaging exercise program, and (b) aspects of functional performance, health knowledge, dietary…
- Conditions
- Activities of Daily Living, Accidental Fall, Sarcopenia, Arteriosclerosis
- Trial name
- Bingocize (NCT03629912)
- Testing
- Socially-Based Exercise Intervention for Older Adults
- Where
- 4 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Western Kentucky University
Sedentary Lifestyle
Healthy Aging Resources to Thrive (HART)
Healthy Aging Resources to Thrive (HART) uses a rigorous two-stage randomized control design, adapted and refined based on pilot studies, to test a novel intervention to reduce sitting time in older adults.
- Trial name
- HART (NCT03739762)
- Testing
- i-STAND, Healthy Living control
- Where
- United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aging, Cognitive Decline
Aging and Cognitive Health Evaluation in Elders (ACHIEVE)
The ACHIEVE study will be a randomized controlled trial nested within the infrastructure of the Atherosclerosis Risk in Communities (ARIC) study.
- Trial name
- ACHIEVE (NCT03243422)
- Testing
- Successful aging health education intervention, Hearing intervention
- Where
- 4 sites in United States
- Volunteers
- 977 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Postmenopausal Symptoms, Aging
Cholinergic Health After Menopause (CHAMP)
Women are at increased risk for Alzheimer's disease (AD). Notably at menopause, some women experience a change in cognition. However, not all women experience negative effects of menopause on cognition.
- Conditions
- Postmenopausal Symptoms, Aging, Alzheimer Disease
- Trial name
- CHAMP (NCT04129060)
- Testing
- Cholinergic antagonist
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Sedentary Behavior, Aging
A Trial of Habit Formation Theory for Exercise in Older Adults
This personalized trial will evaluate the effects of five behavioral change techniques (BCTs) described in Habit Formation Theory (Goal setting, Action Planning, Self-Monitoring, Behavioral Practice/Rehearsal and Habit Formation)…
- Conditions
- Sedentary Behavior, Aging, Activity, Motor, Behavior, Health
- Trial name
- NCT04869644
- Testing
- Goal setting, Action Planning, Self-monitoring of behavior
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Social Isolation, Aging
A Personalized Health Behavior System
The objectives of this study are to examine the usability and efficacy, for diverse older adults, of a new tablet-based dynamic system: the Fittle Senior System (FSS) that will provide: (1) personalized behavior-change programs…
- Conditions
- Social Isolation, Aging, Physical Activity
- Trial name
- FITTLESenior (NCT03538158)
- Testing
- Intervention Condition, Control Condition
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cognitive Aging, Adverse Childhood Experiences
Physical Exercise for Augmenting Cognitive Health (PEACH)
PEACH is a pilot project which is being conducted to determine the feasibility and acceptability of a 12-week home-based exercise intervention among Black and African American adults.
- Trial name
- PEACH (NCT04922710)
- Testing
- Home-based aerobic exercise
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Adherence, Treatment
Smart Reminders to Promote Home-based Cognitive Training
This study will examine whether among older adults an adaptive and personalized reminder system can better support adherence to home-based cognitive training over typical reminder systems.
- Trial name
- NCT05016856
- Testing
- Adherence Promotion With Person-centered Technology (APPT) System, Standard Reminder System (Active Control)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy People Programs
Maintaining Cognitive Health in Aging Veterans
Interventions aimed at disseminating information about cognitive aging and lifestyle factors that contribute to successful cognitive aging, in addition to providing broad cognitive skills training, may improve the psychological…
- Trial name
- NCT02023944
- Testing
- Memory and Aging Course
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obesity, PreDiabetes
Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity and pre-diabetes threatens the overall health and functional independence of older adults but lifestyle weight management for diabetes prevention, soon to be reimbursed by Medicare, can reduce this burden.
- Conditions
- Obesity, PreDiabetes, Aging
- Trial name
- Sustain-DPP (NCT03500640)
- Testing
- DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Aging
Mindfulness Training in Healthy Older Veterans
Evidence shows the positive effects of Brain Health \& Wellness classes in younger individuals. The proposed study investigates the usefulness of these classes in older Veterans aged 50-85.
- Trial name
- MTGHOV (NCT02816723)
- Testing
- Mindfulness-based Stress Reduction, Brain Health
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development