Clinical trials: Health Adult Subjects
Healthy
Metformin and Furosemide Drug-Drug Interaction Study
This study will assess the potential effects of lesinurad on the pharmacokinetics (PK) of metformin and furosemide in healthy, adult male subjects.
- Trial name
- NCT02028689
- Testing
- Lesinurad 400 mg, Metformin 850 mg, Furosemide 40 mg
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ardea Biosciences, Inc.
Health Adult Subjects, Communication
Validation of the Healthcare Relationship Assessment Scale (ERA) in Health Sciences Students.
This study aims to design and psychometrically validate a practical and agile observational instrument-the Healthcare Relationship Assessment scale (ERA scale)-to evaluate communication skills and person-centered care among…
- Conditions
- Health Adult Subjects, Communication, Clinical Communication
- Trial name
- COPS-ERA (NCT07911241)
- Testing
- ERA Scale (Healthcare Relationship Assessment Scale)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Loyola Andalucia
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124573
- Testing
- Sitagliptin/Metformin HCl 100/1000 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Health Adult Subjects, Pressure Injury Prevention
A Trial to Investigate the New Caulis Pro® Low Air Loss (LAL) System
Investigation of biomechanical and physiological functions of laying on a new mattress in healthy volunteers.
- Trial name
- NCT07213739
- Testing
- CLP and pulsation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arjo AB
Health Adult Subjects
Thrower's Ten Versus Conventional Conditioning in Amateur Discus Throwers
This retrospective observational study compares the association of Thrower's Ten training and conventional conditioning with throwing performance and shoulder muscle strength in amateur male discus throwers.
- Trial name
- NCT07783997
- Testing
- Thrower's Ten exercise program, Conventional conditioning program
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saveetha University
Health Adult Subjects, Moderate-to-Severe Atopic Dermatitis
A Phase I Study of HXN5003 in Healthy Participants and Patients With Moderate-to-Severe Atopic Dermatitis
This is a Phase I, multicenter, randomized, double-blind, placebo-controlled study evaluating HXN5003 in healthy participants and patients with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT07801612
- Testing
- HXN5003
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Helixon Biotechnology (Suzhou) Co., Ltd
Pharmacokinetic Analysis, Bioequivalence
Bioequivalence Study of Levetiracetam 1500 mg Coated Granules in Healthy, Male Subjects
Pivotal, single-dose, randomized, open-label, two-period, two-sequence, two-treatment, single-centre, crossover, bioequivalence study of Levetiracetam 1500 mg coated granules in sachet formulations and Keppra (Levetiracetam) 2 x…
- Conditions
- Pharmacokinetic Analysis, Bioequivalence, Health Adult Subjects
- Trial name
- NCT07393022
- Testing
- Levetiracetam 1500 mg, Keppra® 750 mg
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Desitin Arzneimittel GmbH
Neurological Disorders, Health Adult Subjects
A Muscle-brain Interplay Study in Neurological Disorders
Despite the improvements in life expectancy, neurodegenerative diseases (NDGs) have become the most dreaded disorders of older people.
- Trial name
- M-Brain (NCT07477821)
- Where
- 4 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Health Adult Subjects
Impact of a Wheat-based Fermented Beverage on Microbiota and Metabolic Health in Healthy Individuals
The proposed study aims to evaluate the impact on intestinal and oral microbiota composition and the metabolic effects of the daily consumption of a wheat-based fermented beverage, developed under the collaborative WHEATBIOME…
- Trial name
- NCT07560527
- Testing
- Wheat-based fermented beverage
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Health Adult Subjects
Dihydroberberine Effects on Body Composition and Metabolic Health in Healthy Adults
The goal of this clinical trial is to evaluate whether dihydroberberine (DHB) supplementation can improve body composition, blood sugar control, energy levels, appetite, and mood in healthy adults with overweight or mild obesity.
- Trial name
- DHB (NCT07322679)
- Testing
- Dihydroberberine（DHB）
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
N/A - Healthy Subjects
Text Messaging Intervention on Happy Family Meal for Improving Family Communication and Well-being in Hong Kong Adults
Family meals are crucial for family communication and well-being. This text messaging intervention digitalizes Happy Family Kitchen II, a face-to-face community-based intervention previously shown to be effective.
- Trial name
- NCT06747780
- Testing
- Text messaging, Control (Usual care)
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Dr. Wang Man-Ping
Health Adult Subjects
A Study to Evaluate ENERGI-F705 Tablets in Healthy Volunteers
To evaluate the safety, the tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) of ENERGI-F705 Tablets in healthy subjects.
- Trial name
- NCT07650383
- Testing
- ENERGI-F705 Tablets 60 mg, ENERGI-F705 Tablets 120 mg, Vehicle Control
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Energenesis Biomedical Co., Ltd.
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Health Adult Subjects
The Role of Incorporating Acacia Gum in Foods on Glucose Homeostasis in Healthy Humans
Abnormal postprandial blood glucose (PPG) is considered as a strong predictor for developing metabolic diseases worldwide. Nowadays, little understanding is available on how a carbohydrate-rich food matrix and the starch…
- Trial name
- AcaciaGlu (NCT07416643)
- Testing
- incorporating acacia gum flour into commonly consume foods
- Where
- Saudi Arabia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Health Adult Subjects, Obesity & Overweight
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
Randomized, Placebo-controlled Study to determine the safety and tolerability of multiple oral doses of TIX100 administered daily for 28 days to otherwise healthy overweight/obese subjects.
- Trial name
- NCT07675590
- Testing
- TIX100
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- TIXiMED, Inc.
Cardiovascular Risk Factor, Metabolic Syndrome
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk
This cross-over study investigates health effects of dietary intake of whole walnuts towards cardiovascular risk factors in adults under low cardiovascular risk.
- Conditions
- Cardiovascular Risk Factor, Metabolic Syndrome, Hypertension
- Trial name
- FitALA (NCT03227497)
- Testing
- Whole Walnuts
- Where
- Serbia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124560
- Testing
- Sitagliptin/Metformin HCl 100/1000 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Smoking Cessation
A Multi Doses Study to Compare the Pharmacokinetics of BR9003A and BR9003 in Healthy Adult Subjects
This is a randomized, multiple doses, crossover clinical study to compare the pharmacokinetic characteristics and the safety between administration of BR9003 and BR9003A in healthy adult subjects.
- Trial name
- NCT04857047
- Testing
- BR9003 2mg, BR9003A 1mg
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers
The purpose of this study is to evaluate the comparative bioavailability of two fixed dose combination tablet formulations of amlodipine and losartan in healthy volunteers.
- Trial name
- NCT01648231
- Testing
- Reference Treatment: 1 x 5mg amlodipine tablet and 1 x 100mg losartan tablet administered in fasted state, Fixed Dose Combination 1: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state, Fixed Dose Combination 2: 1 x 5mg amlodipine / 100mg losartan tablet administered in fasted state
- Where
- Australia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Lung Cancer (Diagnosis), Health Adult Subjects
Prospective Multicentre Study for the Application of Telomere Measurement Technology as a Tool for Lung Cancer Diagnosis
This research is a clinical performance study of in vitro diagnostic device (IVD), a prospective, multicentre, open-label, case-control clinical investigation aimed at constructing a predictive model that allows results to be…
- Conditions
- Lung Cancer (Diagnosis), Health Adult Subjects, Patient
- Trial name
- PneumoTAV001 (NCT07465848)
- Testing
- Blood sample collection for telomere biomarker analysis, Telomere biomarker analysis
- Where
- 12 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Grupo Español de Investigación en Diagnóstico y Tratamiento Hipertemprano de Enfermedades (GeDiTPhe)