Clinical trials: Healing
Complications Wounds, Negative Pressure Wound Therapy
Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial
Incisional negative pressure therapy (INPWT) has previously been shown in certain patient populations to decrease wound healing complications, decrease the rate of hematomas and seromas, as well as have better scar quality.
- Conditions
- Complications Wounds, Negative Pressure Wound Therapy, Wound Healing Delayed, Incisional
- Trial name
- NCT03010137
- Testing
- Incisional Negative Pressure Wound Therapy, Standard Closure with Skin Glue, PICO (Smith&Nephew)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Tibial Delayed Healing
Tibial Delayed Healing Pivotal Clinical Trial
Evaluate the INFUSE/MASTERGRAFT™ Delayed Healing Device as an alternative/replacement to autograft in the treatment of tibial delayed healing.
- Trial name
- NCT01016067
- Testing
- INFUSE/MASTERGRAFT, Autograft bone
- Where
- 16 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Medtronic Spinal and Biologics
Tooth Extraction
Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft
This entire protocol involves procedures that are standard care. The purpose of the research is to evaluate whether there are any differences in new bone formation following tooth extraction and grafting of the extraction socket…
- Trial name
- NCT01924390
- Testing
- Mineralized freeze-dried bone allograft alone, Combination of Mineralized and demineralized freeze-dried bone allograft alone
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Healthy
Clinical Evaluation of the Photoallergy Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes photoallergic reactions on the skin.
- Trial name
- NCT00645164
- Testing
- Ointment Vehicle, Xenaderm
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Bone Loss
Evaluation of Using Different Screwed Abutment Height
A prospective randomized controlled clinical trial will be conducted. Study groups will be assigned as described above. The patients will be randomly divided into two groups in order to study the influence of prosthetic screw…
- Trial name
- NCT06017115
- Testing
- Dental implant placement with COVER SCREW (two surgeries in control group) or DEFINITIVE TRANSEPITHELIAL ABUTMENT (one surgery in test group)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Healthy
Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes toxic reactions on the skin.
- Trial name
- NCT00644917
- Testing
- Xenaderm
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Tooth Replacement
Dental Implant Study Comparing Two Types of Metals Used for Dental Implants
The purpose of this research study is to compare the healing differences of two metals (trabecular vs. standard titanium) that are used for dental implants.
- Trial name
- ZMU (NCT01714024)
- Testing
- Zimmer Trabecular Metal Test Cylinder, Zimmer Titanium Test Cylinder
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Wound Healing
Patch Test of Benzalkonium Chloride Disinfectant Spray
The aim of the study is to evaluate the irritation potential of benzalkonium chloride disinfectant spray when placed in contact with normal human skin.
- Trial name
- NCT01762982
- Testing
- 0.13% Benzalkonium Chloride, SLS Solution, Normal Saline Water
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Ulcer, Skin Ulcer
Epidermal Grafting in Wound Healing
Split thickness skin grafting is the normal standard of care for wound closure. However, this is an invasive procedure and associated with pain also there can be additional donor site morbidity.
- Conditions
- Ulcer, Skin Ulcer, Wounds and Injuries
- Trial name
- EPIGRAAFT (NCT02535481)
- Testing
- Epidermal grafting, Split thickness skin grafting
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University College, London
Post Traumatic Stress Disorder
Islamic Trauma Healing: Feasibility Study
This study will examine the initial feasibility of a program called Islamic Trauma Healing by conducting a small feasibility study (N = 26) of Islamic Trauma Healing in Somalia on key targets of PTSD, depression, somatic…
- Trial name
- NCT03761732
- Testing
- Islamic Trauma Healing
- Where
- 2 sites in Somalia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Washington
Jaw, Edentulous, Partially
A Study to Evaluate the Effectiveness of Laser-Ablated Implant-Abutments to Promote Tissue Healing
The purpose of this study is to determine which implant-abutment design is more likely to promote early soft-tissue healing processes and/or will enhance longitudinal peri-implant bone and soft-tissue health.
- Trial name
- NCT01822223
- Testing
- Dental implant-abutments
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Loss of Teeth Due to Extraction
Evaluation of Healing at Molar Extraction Sites With and Without Ridge Preservation
Following tooth extraction ridge preservation procedure have been suggested to limit bone resorptive dimensional changes to facilitate prospective implant placement.
- Trial name
- NCT02543398
- Testing
- Ridge preservation
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Surgical Wound
Healing Ointment Usage Post-surgical Procedure
To evaluate benefits of a Healing Ointment in skin improvement after dermatologic procedures
- Trial name
- Cetaphil (NCT05686928)
- Testing
- Cetaphil Healing Ointment
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Effect of Irrigation Activation on Periapical Healing
Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions
The aim of this study was to highlight the healing rates of large periapical lesions after different irrigation activation treatments as manual dynamic activation (MDA), passive ultrasonic irrigation (PUI), shock wave-enhanced…
- Trial name
- NCT06204887
- Testing
- Manual dynamic activation, Passive ultrasonic activation, Laser activation
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Chronic Diabetic Foot Ulcers
Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer
A PHASE 2a, MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED DOSE ESCALATING STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF TOPICALLY APPLIED BISPHOSPHOCIN NU-3 GEL TO CLINICALLY NONINFECTED CHRONIC DIABETIC FOOT…
- Trial name
- NCT05276401
- Testing
- 5% Bisphosphocin Topical Gel, 10% Bisphosphocin Topical Gel
- Where
- 5 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lakewood-Amedex Inc
Epithelium, Corneal
Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
The purpose of this study is a prospective,double-blinded, randomized trial to compare the rate of healing following PRK after the use of two commercially available 4th generation fluoroquinolones, moxifloxacin and gatifloxacin.
- Trial name
- NCT00414011
- Testing
- Moxifloxacin, Gatifloxacin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Inflammatory Bowel Diseases
Regulation of Mucosal Healing in Inflammatory Bowel Disease
The objective of the current study is to compare non-healing colonic ulcers in patients with inflammatory bowel disease (IBD) with iatrogenic colonic ulcers (biopsy sites) in healthy control patients and patients with rheumatoid…
- Trial name
- NCT04504136
- Testing
- Serial Biopsy
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Terrence A Barrett