Clinical trials: Headache
Post-Dural Puncture Headache, Headache After Spinal Puncture
Comparison of Post-Dural Puncture Headache After Spinal Anesthesia Using Median Versus Paramedian Approach
This randomized controlled trial will compare two commonly used techniques for performing spinal anesthesia, the median (midline) approach and the paramedian (lateral) approach, in adult patients undergoing elective orthopedic or…
- Trial name
- NCT07436403
- Testing
- Spinal anesthesia using median approach (midline), Spinal anesthesia using paramedian approach
- Where
- Pakistan
- Volunteers
- 142 people
- Sponsor
- Mayo Hospital Lahore
Migraine, Overweight and Obesity
Very Low Calories Ketogenic Diet in Migraine.
Ketogenesis is a physiologic phenomenon due to starvation or ketogenic diet (KD), a drastic restricted carbohydrate dietary regimen that induces lipid metabolism and ketone body (KB) synthesis.
- Trial name
- Ketomig (NCT03076060)
- Testing
- Ketogenic diet
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Migraine Headache
Autonomic Dysfunction in Patients With Migraine: Cardiovascular and Neurophysiology Assessment
Autonomic dysfunction in patients with migraine: cardiovascular and neurophysiology assessment.
- Trial name
- NCT06798259
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Headache, Migraine
Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
To investigate headache score and accompanying symptoms during and after infusion of the natriuretic peptides.
- Trial name
- NCT01637662
- Testing
- Natriuretic peptides
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Impact of Cessation of Toothpaste in Patients With Migraine Headaches
Certain ingredients in toothpaste have the potential to cause headache. In this clinical trial, the investigators will be replacing toothpaste with saline water in a group of persons with migraine and compare them with another…
- Trial name
- STOP-Migraine (NCT07824661)
- Testing
- Toothpaste Cessation
- Where
- India
- Volunteers
- 106 people
- Sponsor
- St.John's National Academy of Health Sciences
Chronic Migraine Headache, OnabotulinumtoxinA
Botulinum Toxin and/or Greater Occipital Nerve Block for Patients With Chronic Migraine
Chronic migraine is a debilitating neurological disorder that significantly affects patients' daily functioning, mental health, and quality of life.
- Conditions
- Chronic Migraine Headache, OnabotulinumtoxinA, Greater Occipital Nerve Block, Combination Therapy
- Trial name
- NCT07535723
- Testing
- OnabotulinumtoxinA, Greater Occipital Nerve Block (GONB)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Migraine, Migraine With Aura
Gepant treAtments: EffectIveNess and tolERability (GAINER)
The purpose of this prospective and multicentric study is to evaluate the effectiveness and tolerability of rimegepant as acute migraine treatment in a cohort of episodic or chronic migraine patients.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- GAINER (NCT05903027)
- Testing
- Rimegepant 75 MG Disintegrating Oral Tablet
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Chronic Headache
Chiropractic Treatment for Headache Among Children Aged 7-14
The primary aim of the study is to assess the effectiveness of chiropractic manipulation treatment versus placebo treatment in children suffering from headache for more than six months.
- Trial name
- NCT02684916
- Testing
- Chiropractic treatment
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Nordic Institute of Chiropractic and Clinical Biomechanics
Cervicogenic Headache
Instrument Based Fascial Abrasion Versus Myofascial Release Technique in Cervicogenic Headache Patients
Study will be randomized clinical trial. Data will be collected from non probability consecutive sampling technique. Total 44 participants from Rafiqa Hospital and District Headquarter (DHQ) Sargodha will be selected and randomly…
- Trial name
- NCT05249647
- Testing
- Instrument based Fascial abrasion technique, Myofascial release technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Chronic Migraine, Headache
Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4
This ClinicalTrials.gov record pertains only to the clinical trial described below in Aim 4. Aims 1-3 and 5 are described here as background information.
- Trial name
- NCT03465826
- Testing
- PainCOACH Pain Coping Skills Training, Treatment as Usual
- Sponsor
- Wake Forest University Health Sciences
Migraine
Prochlorperazine Versus Prochlorperazine & Ketorolac in Treatment of Pediatric Migraine in the Emergency Department
The aim of this study is to evaluate whether the use of prochlorperazine and ketorolac in combination lead in a larger reduction in pain score compared to prochlorperazine alone when treating pediatric migraine in the Emergency…
- Trial name
- NCT01534806
- Testing
- Ketorolac
- Where
- United States
- Sponsor
- Akron Children's Hospital
Headache
Neuromodulation Treatment of Vestibular Migraines
This is a non-randomized pilot study to test the efficacy of neuromodulation via caloric stimulation on vestibular migraines. All subject who meet the study criteria will be in an active treatment group.
- Trial name
- NCT02866084
- Testing
- Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Cluster Headache
Prophylactic Effects of Psilocybin on Chronic Cluster Headache
The purpose of this study is to investigate the prophylactic effects of psilocybin in chronic cluster headache. Subjects will receive a low dose of psilocybin during 3 sessions spaced by one week.
- Trial name
- EPOCH (NCT04280055)
- Testing
- Psilocybin
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Gitte Moos Knudsen
Migraine
Study of the Glymphatic System in Migraine
This study aimed to investigate the role of the glymphatic system in the initiation of migraine attacks, using non-invasive magnetic resonance imaging techniques and a validated model of migraine induction by nitroglycerin…
- Trial name
- NCT05907655
- Testing
- Nitroglycerin 0.3 MG, MRI, Blood sampling
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
New Persistent Daily Headache
NDPH Biomarker Study in Children and Adolescents
This study will recruit pediatric patients with NDPH (New Daily Persistent Headache), characterize their headache in a standard manner, and treat the NDPH with standard medications used for treatment of headaches in this…
- Trial name
- NCT06018025
- Testing
- CGRP antibody
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Duke University
Headache, Emergencies
Predictive Score for Non-traumatic Secondary Headache After an Emergency Call
The study objective was to identify predictive criteria of severe non-traumatic secondary headache among the information gathered during telephone interview conducted by the on-call regulating physician at the Centre15.
- Trial name
- CEPHAREG (NCT04617808)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 715 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Headache, Temporomandibular Disorder
Temporamandibular Joint Functions and Parafunctional Habits
Headache is the most common type of pain in children and adolescents with effects on health-related quality of life (HrQoL), school attendance, and social functioning.
- Trial name
- NCT05580276
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Karadeniz Technical University
Migraine Disorders, Headache Disorders, Primary
Individualized Prediction of Migraine Attacks Using a Mobile Phone App and Fitbit
This trial is collaboration between Mayo Clinic, Second Opinion Health (Simon Bloch, simon@somobilehealth.com 408-981-3814) and Allergan.
- Conditions
- Migraine Disorders, Headache Disorders, Primary, Headache Disorders, Brain Diseases
- Trial name
- Migraine Alert (NCT02910921)
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Second Opinion Health
Bruxism, Sleep
Investigation of Respiratory Function in Bruxism
The aim of the study was to evaluate the respiratory functions, sleep quality and headache severity of individuals with bruxism and to compare them with the control group without bruxism.
- Trial name
- NCT07133035
- Testing
- Pulmonary function test, Fonseca Anamnestic Index, Jenkins Sleep Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atılım University
Tension-type Headache
Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.
The aim is to investigate muscle soreness and stiffness in patients with Chronic or Frequent Episodic Tension Type Headache before and after treatment with amitriptyline - and to compare the results with healthy individuals.
- Trial name
- NCT02746250
- Testing
- Amitriptyline
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center