Clinical trials: HbA1c
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Type 2 Diabetes Mellitus, Peritoneal Dialysis
A Study of Adding Linagliptin to Control Glycemic Variability and HbA1c in Peritoneal Dialysis Patients With Type 2 Diabetes(PDPD) With Premixed Insulin Therapy
In china, there are the most population of type 2 diabetes mellitus (DM) among the world and DM becomes currently the second cause for end-stage renal disease (ESRD).
- Trial name
- NCT03320031
- Testing
- Linagliptin, Humalog Mix 75/25
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Yanbing Li
HBA1c, Body Weight
Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes
This study examines prospectively the safety and efficacy of switching from multiple daily insulin injections (MDI) to once daily IDegLira (insulin degludec and liraglutide fix ratio combination), a fixed-ratio combination of…
- Conditions
- HBA1c, Body Weight, Hypoglycemia
- Trial name
- NCT04020445
- Testing
- de-escalation of complex insulin regimens
- Where
- Hungary
- Volunteers
- 150 people
- Sponsor
- Bekes County Central Hospital
Diabetes, Metabolic Diseases
The Fasting II Study
This study will determine whether an intensive fasting protocol alters hemoglobin A1c measurements or other markers of metabolic and cardiovascular risk by performing a 5-week clinical trial of fasting among 12 pre-diabetic…
- Trial name
- NCT01792986
- Testing
- water-only 24-hour fasting once per week for 6 weeks
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intermountain Health Care, Inc.
Diabetes Mellitus, Kidney Diseases
Evaluation of the Analytical Performance of ALLEGRO™ Instrument
To assess the performance of the Allegro in the hands of CLIA-Waived Point-of-Care users in at least three distinct Point-of-Care clinical settings and compare the performance characteristics to other accepted Point-of-Care…
- Conditions
- Diabetes Mellitus, Kidney Diseases, Metabolic Disease
- Trial name
- NCT04096313
- Testing
- HbA1c, Lipids, UACR
- Where
- 3 sites in United States
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Nova Biomedical
Type 1 Diabetics Who Are Pregnant or Planning Pregnancy
Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial
The primary objective of the study is to determine if RT CGM (Real Time-Continuous Glucose Monitoring) can improve glycemic control in women with T1D who are pregnant or planning pregnancy.
- Trial name
- CONCEPTT (NCT01788527)
- Testing
- CGM
- Where
- 31 sites in United States, Canada and 4 more
- Volunteers
- 325 people
- Sponsor
- Mount Sinai Hospital, Canada
Type 2 Diabetes Mellitus (T2DM)
Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin
This clinical trial is studying whether combining two commonly used diabetes medications into a single pill works better than taking them separately for people with type 2 diabetes who are already on metformin.
- Trial name
- CONTROL (NCT07057479)
- Testing
- Fixed-dose combination of SGLT2 inhibitor and thiazolidinedione, Control Group 1 Intervention - SGLT2 inhibitor monotherapy, Control Group 2 Intervention - Thiazolidinedione monotherapy
- Where
- Brazil
- Sponsor
- Eurofarma Laboratorios S.A.
Type 2 Diabetes
Mobile Phone Support for Adults and Support Persons to Live Well With Diabetes
This study evaluates a mobile phone-delivered intervention (FAMS 2.0; Family/friend Activation to Motivate Self-care) designed to help adults with type 2 diabetes set and achieve self-care goals and improve the quality of…
- Trial name
- FAMS 2 (NCT04347291)
- Testing
- FAMS 2.0, Print Materials
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- Vanderbilt University Medical Center
Prediabetic State
RCT of a Polyherbal Dietary Supplement for Prediabetes
The primary purpose of this study is to evaluate the impact of a polyherbal dietary supplement (Designs for Health - GlucoSupreme™ Herbal) on markers of glycemic control and other structure/function outcomes among a sample of…
- Trial name
- NCT03388762
- Testing
- GlucoSupreme™ Herbal
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Chronic Periodontitis, Diabetes Mellitus, Type 2
Effectiveness of Non-surgical Periodontal Treatment on HbA1c Levels in a Patient With Type 2 Diabetes Mellitus
This study evaluates the effectiveness of an intervention, non-surgical periodontal treatment (SPR), in patients with poorly controlled type 2 diabetes mellitus and moderate-severe periodontal disease aimed at reducing HbA1c…
- Trial name
- NCT04051866
- Testing
- Non-surgical periodontal treatment: Scaling and root planing (SRP), Oral hygiene instructions
- Where
- Spain
- Sponsor
- Gerencia de Atención Primaria, Madrid
Cardiovascular (CV) Risk, Healthy Eating Index
Pulses: Optimizing Pulse Consumption for Cardiometabolic Health
This randomized clinical trial aims to evaluate the effects of consuming two different doses of pulses (1.5 cups/week or 3 cups/week) in individuals with baseline intake below 1.5 cups/week, compared to a control group receiving…
- Conditions
- Cardiovascular (CV) Risk, Healthy Eating Index, HbA1c, Lipid Profile
- Trial name
- NCT06861153
- Testing
- Pulses 1.5 cups Group, Pulses 3 cups Group, My Plate Group (Control)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Type 2 Diabetes Mellitus, Hyperglycemia
MedStar Health Type 2 Diabetes Pathway to Control
A Diabetes Institute (MDI), in partnership with key stakeholders-including Primary Care Providers- in a northeastern US regional, mixed-payer healthcare system), seeks to implement an evidence-based, technology-enabled…
- Trial name
- T2DMBC (NCT02925312)
- Testing
- Diabetes Pathway
- Where
- United States
- Volunteers
- 419 people
- Sponsor
- Medstar Health Research Institute
Type 1 Diabetes
Liraglutide in the Treatment of Type 1 Diabetes Mellitus
Hypothesis 1: Treatment with Liraglutide in patients with type 1 diabetes decreases fasting, postprandial and the overall mean glucose concentrations.
- Trial name
- NCT01722266
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Pre-Diabetes, Diabetes
A1c FIT TEST: An Epidemiological Study Correlating Hemoglobin A1c With Results of the Air Force Physical FITness TEST.
The purpose of this study is to evaluate the prevalence of pre-diabetes and diabetes among those Air Force personnel who have not passed the Air Force physical fitness test (AFPT) and to evaluate the usefulness of the AFPT as a…
- Conditions
- Pre-Diabetes, Diabetes, Cardiovascular Risks
- Trial name
- NCT01301339
- Where
- United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Type2Diabetes, Diabetes
QBSafe: a Randomized Trial of a Novel Intervention to Improve Care for People Living With Type 2 Diabetes.
Glycemic control is often the main indicator of successful diabetes care, but a singular focus on glycemic control may lead to patients' overall health and wellbeing being overlooked or undervalued.
- Trial name
- NCT05553912
- Testing
- QBSafe
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Yale University
Diabetes Mellitus Type 1
Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 Diabetes
This study is to compare metabolic control, treatment satisfaction, and quality of life during continuous subcutaneous insulin infusion (CSII ) therapy with a new insulin pump system with multiple daily injections (MDI) therapy.
- Trial name
- Insight Kids (NCT02403375)
- Testing
- Accu-Chek Insight Pump System
- Where
- 9 sites in Austria, Germany and 1 more
- Volunteers
- 43 people
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetes Mellitus (T2DM)
Interventional Study of Active Weight Management in Patients With Type 2 Diabetes and Obesity in Routine Clinical Practice During 12 Months.
This study was aimed to achieve of long-term weight loss in T2DM patients by use of comprehensive lifestyle changes program, providing patients with structured diet, exercise plan, group behavioral support and group education.
- Trial name
- NCT02670928
- Testing
- Lifestyle intervention
- Where
- 2 sites in Russia
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Type 2
Relationship Between HbA1c, Fasting Plasma Glucose, Post-prandial Glucose and Other Measures of Glycemic Control
This study aims to evaluate relative contributions of fasting plasma glucose and postprandial glucose at various HbA1c levels using 6-day CGM.
- Trial name
- NCT02117154
- Testing
- 6-day Continuous Glucose Monitoring System
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- University of Malaya
Diabetes Mellitus, Type 2
Problem Solving Treatment for Diabetes in Individuals With Poor Diabetes Control
The goal of this randomised controlled trial is to test a cognitive-behavioural intervention, Problem Solving Treatment for Diabetes (PST-D) in patients with type 2 diabetes.
- Trial name
- RESONATE (NCT05651490)
- Testing
- Problem Solving Treatment for Diabetes, Attention Control Group
- Where
- Singapore
- Volunteers
- 106 people
- Sponsor
- Singapore Eye Research Institute
Gestational Diabetes Mellitus
Glycemic Objectives of Women With Gestational Diabetes Mellitus
In a previous study, the investigators established the dosage of foetal glycated hemoglobin (FGH). It represents the mean of blood sugar 4-6 before the delivery.
- Trial name
- NCT02478762
- Testing
- Normal glycemic control, Low glycemic control
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Université de Sherbrooke