Clinical trials: Hashimoto's Disease
Thyroid, Obesity
Thyroid in Bariatric Surgery
This study is expected to provide novel data regarding potential structural and functional changes of the thyroid gland in morbidly obese adults following significant weight loss through bariatric surgery.
- Conditions
- Thyroid, Obesity, Insulin Resistance, Autoimmune Thyroiditis
- Trial name
- ThyrBar (NCT03048708)
- Testing
- Bariatric surgery
- Volunteers
- 10 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Hashimoto Thyroiditis
The Effect of Hydroxychloroquine Treatment in Hashimoto's Thyroiditis
Hashimoto's thyroiditis is an autoimmune thyroid disease, which induced chronic inflammation of thyroid gland and destroys thyroid tissue.
- Trial name
- NCT01760421
- Testing
- Hydroxychloroquine
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Hashimoto Disease, Adrenal Insufficiency
Isolated ACTH Deficiency in Patients With Hashimoto Thyroiditis
The purpose of this study is to determine whether patients with Hashimoto thyroiditis and impaired well-being may have a partial secondary adrenocortical insufficiency.
- Trial name
- NCT00552487
- Testing
- synacthen
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Sjögren, Autoimmune Thyroid Disease
Prevalence of Pre-clinical Sjögren Disease and Other Immune Disturbances in Subjects With Autoimmune Thyroiditis Disease
The main study hypothesis is that Sjögren Disease (SD), usually considered a disorder typical of adult females, may occur not exceptionally in adolescence or even in childhood as a subclinical process.
- Trial name
- NCT06324578
- Testing
- AT Testing
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Burlo Garofolo
Thyroiditis Autoimmune
Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT
Over the past 10 years, several clinical studies have suggested that selenium supplementation may influence the natural history of AIT.
- Trial name
- NCT02302768
- Testing
- Selenomethionine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Siena
Thyroid Eye Disease, Graves Orbitopathy
A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall objective is to study the safety, pharmacokinetics and efficacy of linsitinib (a small molecule IGF-1R inhibitor) administered orally twice daily (BID) vs.
- Conditions
- Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases
- Trial name
- LIDS (NCT05276063)
- Testing
- Linsitinib
- Where
- 30 sites in United States, Canada and 3 more
- Volunteers
- 90 people
- Sponsor
- Sling Therapeutics, Inc.
Hashimoto Disease, Treatment Levothyroxine
Effect of Treatment for Vitamin D Deficiency on Thyroid Function and Autoimmunity in Hashimoto's Thyroiditis.
The objective of this study is to evaluate the effect of vitamin D supplementation on thyroid autoimmunity, thyroid function, and other metabolic and clinical variables associated with the thyroid axis in patients with…
- Conditions
- Hashimoto Disease, Treatment Levothyroxine, Vitamin D Deficiency
- Trial name
- NCT04778865
- Testing
- Vitamin D-correction, Vitamin D-RDA
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Autoimmune Thyroiditis
A Study of Selenomethionine and Myo-inositol(SOLOWAYS_TM) in Patients With Autoimmune Thyroiditis Carrying the DIO2 Thr92Ala Polymorphism
This pilot, genotype-stratified clinical trial aims to evaluate the safety and preliminary efficacy of combined selenomethionine and myo-inositol supplementation in patients with autoimmune thyroiditis (AIT), including…
- Trial name
- NCT06867913
- Testing
- Supplement groupx
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- S.LAB (SOLOWAYS)
Hypothyroidism, Hashimoto Disease
Gluten Free Diet in Hashimoto's Hypothyroidism
Hashimoto's thyroiditis is an autoimmune condition that reduces functioning of the thyroid gland and can lead to a substantial decline in quality of life for patients, with impacted patients often describing unremitting brain…
- Trial name
- NCT07060118
- Testing
- Gluten Free Diet in Hashimoto's Hypothyroidism
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Selenium
Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
- Trial name
- NCT04942769
- Testing
- Selenium
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Chao Yang Hospital
Hashimoto Thyroiditis, Mediterranean Diet
The Impact of Change of Thyroid Antibodies on Hormone Level and Disease Burden in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is an autoimmune disease affecting the thyroid gland and is one of the most common causes of hypothyroidism. Eating habits may affect the risk of several inflammatory and immune diseases, such as HT.
- Trial name
- Anti-TPO/TG (NCT07048821)
- Testing
- Dietary modification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherihan AboElyazed Mohamed Khalil
Hashimoto's Thyroiditis
Hashimoto's Thyroiditis in Upper Egypt
The aim of this study is to evaluate the pathological pattern, characteristic features, treatment, complications and prognosis of Hashimoto's thyroiditis in upper Egypt.
- Trial name
- NCT06603415
- Testing
- Total thyroidectomy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Thyroid Eye Disease, TED, Graves Orbitopathy
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease (TED).
- Trial name
- ORBIT (NCT07753603)
- Testing
- linsitinib
- Where
- 18 sites in United States
- Volunteers
- 130 people
- Sponsor
- Sling Therapeutics, Inc.
Thyroid Diseases, Hypothyroidism
The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With Hashimato
The goal of this clinical trial is to investigate The effects of an anti-inflammatory diet with or without curcumin supplementation on anthropometric measurements, concentrations of thyroid hormones, anti-TPO, and systemic…
- Conditions
- Thyroid Diseases, Hypothyroidism, Hashimoto Disease
- Trial name
- NCT05975866
- Testing
- curcumin, Anti-inflammatory diet
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- National Nutrition and Food Technology Institute
Thyroid Eye Disease, Graves Orbitopathy
Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
The overall study objective is to continue to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of linsitinib in subjects who were enrolled in the prior VGN-TED-301 through Week 24.
- Conditions
- Thyroid Eye Disease, Graves Orbitopathy, Endocrine System Diseases, Eye Diseases
- Trial name
- NCT06112340
- Testing
- linsitinib
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Sling Therapeutics, Inc.
Hashimoto Thyroiditis
Adjuvant Therapeutic Effect of Vitamin D on Hashimoto's Thyroiditis
The purpose of this study is to explore the relationship between vitamin D and Hashimoto's thyroiditis and to explore whether vitamin D can play an adjuvant role in the treatment of Hashimoto's thyroiditis.
- Trial name
- NCT05871957
- Testing
- Vitamin D Drops
- Volunteers
- 30 people
- Sponsor
- Qianfoshan Hospital
Hashimoto Disease
Single Ascending and Multiple Dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male and Female Adult Subjects
Double-blind, placebo-controlled, single ascending and multiple dose study. Approximately 32 healthy adult male and female subjects will be given a single capsule of MYMD1 to determine its safety, tolerability, and…
- Trial name
- NCT05077865
- Testing
- MYMD-1
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TNF Pharmaceuticals, Inc.
Hashimoto Disease, Psoriasis
Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis
Hashimoto's disease (HT) and psoriasis (PsO) have a significant impact on patient's quality of everyday life, and early diagnosis is critical for the symptoms management and prognosis.
- Trial name
- METHAP (NCT04693936)
- Testing
- Nutraceutical Combination Plan
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Crete
Autoimmune Thyroiditis
Low-Level Laser Therapy in Chronic Autoimmune Thyroiditis
The purpose of this study is to evaluate whether low-level Laser therapy is effective in ameliorating the thyroid function of patients with hypothyroidism caused by chronic autoimmune thyroiditis.
- Trial name
- NCT01129492
- Testing
- Low-level Laser therapy
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- University of Sao Paulo General Hospital
Hashimoto Thyroiditis, Subacute Thyroiditis
Colchicine for Autoimmune and Subacute Thyroiditis
Thyroiditis includes inflammatory thyroid disorders such as Hashimoto's thyroiditis and subacute thyroiditis. These conditions may cause thyroid pain, neck tenderness, elevated inflammatory markers, thyroid dysfunction, fatigue…
- Conditions
- Hashimoto Thyroiditis, Subacute Thyroiditis, Thyroiditis
- Trial name
- COLTHYR (NCT07571681)
- Testing
- colchicine, Prednisolone, NSAID
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- Mansoura University