Clinical trials: Harmful Use
Chronic Kidney Diseases, Heart Failure
Patient Education Video to Reduce OTC NSAIDs
The goal of this study is to assess the efficacy of a brief 3 to 5-minute educational video on influencing intent to change behavior regarding potentially harmful over-the-counter (OTC) NSAID use in adults with chronic kidney…
- Conditions
- Chronic Kidney Diseases, Heart Failure, Hypertension
- Trial name
- NCT06575205
- Testing
- Educational video
- Where
- United States
- Volunteers
- 1,452 people
- Sponsor
- Carilion Clinic
Alcohol Use, Underage, Harmful; Use, Alcohol
Efficacy of the Expectancy Challenge Alcohol Literacy Curriculum on Reducing College Student Alcohol Use and Harms
The current project uses a web-based program called the Expectancy Challenge Alcohol Literacy Curriculum (ECALC) to reduce alcohol use and associated harms among college students.
- Trial name
- ECALC (NCT05616247)
- Testing
- ECALC, ECALC Plus Weekly Boosters
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Narcotic Use, Postoperative Pain
A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
There was a study titled "A prospective evaluation of opioid utilization after upper extremity surgical procedures: Identifying consumption patterns and determining prescribing guidelines" by Dr.
- Conditions
- Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use
- Trial name
- Opioids (NCT03422211)
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- St. Louis University
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Insomnia, Alcohol; Harmful Use
The Insomnia Treatment and Problems Study for Veterans
This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes.
- Trial name
- iTAP-V (NCT03804788)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygeine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alcohol Use Disorder, Alcohol-Related Injury
Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon
Brief Summary Alcohol use is a major contributor to injury burden in Cameroon, particularly among trauma patients presenting to emergency departments.
- Conditions
- Alcohol Use Disorder, Alcohol-Related Injury, Trauma
- Trial name
- NCT07677449
- Testing
- Cameroon-Adapted SBIRT, Usual Care
- Where
- Cameroon
- Volunteers
- 690 people
- Sponsor
- University of Buea
Alcoholic Intoxication, Wounds and Injuries
Phone Intervention for Alcohol (ETOH) Use in Emergency Department Motor Vehicle Crash (ED MVC) Patients
The purpose of this study is to determine if a brief counseling intervention, delivered by telephone, is more effective than standard ED care, to reduce future alcohol related injuries and alcohol related negative consequences…
- Trial name
- DIAL (NCT00457548)
- Testing
- Brief Telephone Counseling for risky aclohol use
- Sponsor
- Rhode Island Hospital
Heavy Drinking, Harmful; Use, Alcohol
A PPG Sensor-Based Feedback Intervention for Heavy Drinking Young Adults
Heavy alcohol use among young adults is a significant public health problem. Advances in technology may offer an innovative solution.
- Trial name
- NCT05090995
- Testing
- Behavioral Self-Management and Feedback, Behavioral Self-Management
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse, Harmful Alcohol Use
Improving Help-seeking Propensity Through a Micro-intervention Targeting Common Concerns Among Individuals With Alcohol Problems: A Randomized Controlled Experiment
Many people who have risky alcohol use or alcohol dependence do not seek help, often is due to concerns about potential consequences or feelings of shame.
- Conditions
- Alcohol Abuse, Harmful Alcohol Use, Hazardous Alcohol Use, Hazardous Drinking
- Trial name
- NCT06675812
- Testing
- Information intervention
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Alcohol Consumption, Alcohol; Harmful Use
Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems
Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway.
- Conditions
- Alcohol Consumption, Alcohol; Harmful Use, Health Risk Behaviors, Alcohol Dependence
- Trial name
- NCT04164940
- Testing
- Brief alcohol intervention
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- Helse Stavanger HF
Alcohol Drinking, Alcohol Use Disorder
Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study
In this study, the investigators aim to capture inter- and intra-brain mechanisms underlying alcohol reward in novel social context.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT06687525
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Insomnia, Alcohol; Harmful Use
Insomnia Treatment and Problems (the iTAP Study)
This project aims to evaluate the efficacy of insomnia treatment in improving insomnia symptoms and alcohol-related problems among heavy-drinking young adults.
- Trial name
- iTAP (NCT03627832)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep Hygiene
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Post-operative Pain, Acute, Cesarean Section
Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator
Post-cesarean section (CS) pain is commonly treated with acetaminophen, ibuprofen, and opioid medications as needed following delivery.
- Conditions
- Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
- Trial name
- NCT06434714
- Testing
- Auricular percutaneous nerve field stimulator
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Alcohol Drinking, Alcoholism
Digital Human-Based Brief Interventions for Harmful Alcohol Use: The PAHOLA Project
Alcohol use disorders are among the most prevalent mental disorders in Canada; however, due to numerous barriers, including fear of treatment, privacy concerns, stigma, time conflicts, and lack of availability of treatment, less…
- Trial name
- NCT05906979
- Testing
- PAHOLA (digital health assistant), Standard information on alcohol use and health
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Metabolic Disturbance, Alcohol; Harmful Use
Metabolic Effects of One-weak Heavy Drinking
Examination of the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.
- Conditions
- Metabolic Disturbance, Alcohol; Harmful Use, Glucose Intolerance
- Trial name
- ROSMET (NCT04229550)
- Testing
- Festival participation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Substance Use
Impact of a Computer-Assisted SBIRT Program in an HIV Care Setting
The goal of this research is to assess the impact of the "screening, brief intervention, and referral to treatment" (SBIRT) intervention strategy for harmful substance use among HIV-positive people.
- Trial name
- SBIRT (NCT01300806)
- Volunteers
- 210 people
- Sponsor
- University of California, San Francisco
Insomnia, Alcohol; Harmful Use
Sleep as a Mechanism of Change in Alcohol Use
This project aims to evaluate improvement of insomnia as a mechanism of improvement in alcohol use outcomes.
- Trial name
- ReTRAIN (NCT06286774)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Covid-19, Coronavirus, Angiotensin Converting Enzyme Inhibitors, Influenza, Electronic Health Records, Epidemiology, Comorbidity, Incidence, United Kingdom
The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective?
The study use UK based linked electronic health records from the Clinical Research Datalink (CALIBER) of 5.6 million individuals to conduct a matched case-control study to investigate the incidence of influenza in individuals…
- Trial name
- NCT04322786
- Testing
- ACE inhibitor
- Volunteers
- 1,302,508 people
- Sponsor
- University College, London
Tobacco; Use, Harmful
The Influence of Electronic and Traditional Cigarettes Smoking on Hemodynamic Parameters
It is intended to examine 50 healthy volunteers aged 18 - 60 years. 12-hour abstinence from tobacco smoke, alcohol or coffee before the experiment will be required.
- Trial name
- EPAPHemo (NCT03037775)
- Testing
- Baseline, e-cigarette without nicotine, e-cigarette with nicotine
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections
The proposed study involves conducting a larger-scale study exploring Game Plan's effects among MSM in the real-world, alongside innovative approaches for expanding HIV testing.
- Trial name
- NCT04552171
- Testing
- Access to Game Plan app and 24-hour helpline
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Brown University